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Chesterfield, United Kingdom Clinical Trials

A listing of Chesterfield, United Kingdom clinical trials actively recruiting patients volunteers.

RESULTS

Found (19) clinical trials

The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII (ACCoRd)

Study design: Randomised, controlled, multi-centre, open-label, phase III trial (with a single intervention registration phase). Primary Objectives The primary objectives of this study are to determine: The impact on Depth of Response (DoR: less than VGPR versus VGPR or better) when salvage ASCT conditioning is augmented by the addition of ...

Phase

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An Open Randomised Trial of the Arabin Pessary to Prevent Pre-term Birth in Twin Pregnancy

STOPPIT-2 is a multicentre open label randomised controlled trial of the Arabin pessary (CE marked Device) versus Standard treatment in women with twin pregnancy. The study is in two phases - a SCREENING phase, in which women with a short cervix (cervical length of ( less or equal to 35mm) ...

Phase N/A

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Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

The primary objective of the IMPRESS Trial will be to compare the proportion of patients undergoing any radical treatment in the two arms of the study. Another primary endpoint is to measure the difference in detection of high risk patients when comparing CT and MRI for all patients. Secondary outcomes ...

Phase N/A

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Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN

Chronic heart failure (CHF) is a very common medical problem. Despite improvements in treatment, many patients suffer limiting symptoms of shortness of breath and fatigue. Hospitalisation for CHF is common and life expectancy reduced. Many patients with CHF have a deficiency of iron (low iron levels or cannot use iron ...

Phase

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An Investigational Study to Evaluate Experimental Medication BMS-986165 Compared to Placebo and a Currently Available Treatment in Participants With Moderate-to-Severe Plaque Psoriasis

The purpose of this study is to investigate the experimental medication BMS-986165 compared to placebo and a currently available treatment in participants with moderate to severe plaque psoriasis.

Phase

0.74 miles

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A Randomized Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF Patients

The purpose of this study is to demonstrate the superiority of LCZ696 over individualized medical therapy for comorbidities in reducing N-terminal pro-brain natriuretic peptide (NT-proBNP) and improving HF symptoms and functional capacity in patients with heart failure with preserved ejection fraction (HFpEF).

Phase

0.89 miles

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The British Heart Foundation SENIOR-RITA Trial

The population is getting older and heart artery disease is the biggest killer in the UK. Over recent years, there have been improvements in medications and technologies to treat it, but these have been primarily tested in younger patients. Previous research studies suggest that older patients (75 years and over) ...

Phase N/A

0.89 miles

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A Longitudinal Investigation of Skin Barrier Development From Birth and the Validation of Early Predictors of Atopic Eczema Risk: the Skin Testing for Atopic Eczema Risk (STAR) Study

The primary aim of this study is to investigate the relationship between skin barrier structure/function and skin health in a longitudinal birth cohort. The study (including the purpose and design) has been externally reviewed by a group of peers and was awarded funding by the Leo Foundation. There is no ...

Phase N/A

7.76 miles

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Tamoxifen in Patients With Oesophageal Cancer

Oesophageal cancer is the eighth most common cancer worldwide, and the United Kingdom (UK), has the world's highest incidence of oesophageal adenocarcinoma. The 5- year survival for patients diagnosed with oesophageal cancer during 2010-2011 in England and Wales was 15%. Ten- year survival for oesophageal cancer in the UK ranks ...

Phase

8.44 miles

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The Use of Social Stories to Reduce Negative Affect and Improve Satisfaction in Adults Attending an ASD Assessment

An invitation to participate in the study will be included with every appointment letter sent out by the host site(s) whilst recruitment is active. The invitation will invite participants to visit a website (hosted by Qualtrics) where they will be provided with information about the study and asked if they ...

Phase N/A

9.29 miles

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