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Addenbrooke's Hospital, Cambridge, United Kingdom Clinical Trials

A listing of Addenbrooke's Hospital, Cambridge, United Kingdom clinical trials actively recruiting patients volunteers.

RESULTS

Found (34) clinical trials

Unravel MGUS (Monoclonal Gammopathy of Unknown Significance)

Monoclonal gammopathy of unknown significance (MGUS) is a common haematological condition. It is characterised by proliferation of a B lymphocyte clone and it's associated antibody (paraprotein). In most cases there are no clinical symptoms, however, in a small number of individuals there may be an interaction of the paraprotein with ...

Phase N/A

0.03 miles

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Cambridge Liquid Biopsy and Tumour Profiling Study for Patients on Experimental Therapeutics Trials

Some patients respond to anti-cancer drugs whilst others do not, despite having tumours with, apparently, similar characteristics such as site of origin. This variability in response can in some cases be explained by the genetic profile of the tumour. Therefore, studying the relationship between the molecular profiles of individual cancers ...

Phase N/A

0.03 miles

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Validation of Structured Light Plethysmography - Health and Disease

The investigators hypothesize that SLP may be a useful tool to differentiate between different respiratory diseases. To further examine differences in disease and health, and between diseases SLP measurements will be recorded in a range of diagnostic conditions that effect breathing and in healthy normal subjects. This is a non-randomised ...

Phase N/A

0.03 miles

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A Long-Term Registry of Humira (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)

This is a registry study to evaluate the long-term safety and effectiveness of adalimumab in patients with moderately to severely active UC who are treated as recommended in the product label.

Phase N/A

0.03 miles

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ADVATE Hemophilia A Outcome Database (AHEAD)

The purpose of the study is to document the natural history of hemophilia. A disease and long-term outcomes in terms of effectiveness, safety and quality of life (QoL) in participants receiving ADVATE in routine clinical practice. Participants may use any treatment regimen, including on-demand and prophylaxis using standardized regimens or ...

Phase N/A

0.03 miles

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Molecular Imaging and Spectroscopy With Stable Isotopes in Oncology and Neurology

This is a single-centre prospective physiological study. Participants will be recruited through MDTs and clinics. Baseline screening blood tests will be performed. Baseline MRI will be undertaken to identify lesions to be studied. This will be followed by hyperpolarised carbon-13 MRSI after the injection of hyperpolarised 13C-pyruvate. Scanning with 18F-FDG ...

Phase N/A

0.03 miles

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Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

The primary objective of Enroll-HD is to develop a comprehensive repository of prospective and systematically collected clinical research data (demography, clinical features, family history, genetic characteristics) and biological specimens (blood) from individuals with manifest HD, unaffected individuals known to carry the HD mutation or at risk of carrying the HD ...

Phase N/A

0.14 miles

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Study of Genes and Environment in Patients With Breast Cancer in the East Anglia Region of the United Kingdom

OBJECTIVES: - To obtain epidemiological information and biological material on a population-based series of breast cancer cases. - To establish whether polymorphisms in putative cancer predisposition genes are associated with an increased risk of breast cancer by comparing the frequency of alterations in breast cancer patients with the corresponding frequency ...

Phase N/A

0.36 miles

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Study of Genes and the Environment in Patients With Ovarian Cancer in the East Anglia Oxford Trent or West Midlands Regions of the United Kingdom

OBJECTIVES: - To obtain epidemiological information and biological material on a population-based series of ovarian cases. - To define the proportion of ovarian cancer incidence attributable to mutations in known predisposing genes (e.g., BRCA1 and BRCA2). - To determine the risk associated with predisposing mutations by examining the cancer risks ...

Phase N/A

0.36 miles

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Study of Genes and Environment in Patients With Cancer in East Anglia Trent or West Midlands Regions of the United Kingdom

OBJECTIVES: - To obtain epidemiological information and biological material on a population-based series of cancer cases, including malignant melanoma, lymphoma, bladder, kidney, esophageal, and pancreatic cancer, and brain tumors. - Identify novel cancer susceptibility genes, by comparison of genotype frequencies in cases with the corresponding frequencies in large control series. ...

Phase N/A

0.36 miles

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