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Goeteborg, Sweden Clinical Trials

A listing of Goeteborg, Sweden clinical trials actively recruiting patients volunteers.

RESULTS

Found (199) clinical trials

Disulfiram in Recurrent Glioblastoma

Disulfiram (Antabuse) is a well-tolerated, cheap, generic drug that has been in use since the 1950s to treat alcoholism. There is now an increasing amount of independent preclinical data to support disulfiram as an anticancer agent. The potency of disulfiram as an anticancer agent seems strengthened by copper. There is ...

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BROnchoalveolar Investigations of Never-smokers With Chronic Obstruction From the Swedish CardioPulmonary bioImage Study

Chronic Obstructive Pulmonary Disease (COPD) is an umbrella diagnosis defined by obstructive lung function impairments, and is likely to be caused by a multitude of etiologies including environmental exposures, genetic predispositions and developmental factors. Due to the heterogeneity of the disease, molecular and mechanistic sub-phenotyping of COPD represents an essential ...

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Glycosaminoglycan Scores as Predictive Biomarkers in Advanced Renal Cell Carcinoma

In this study, glycosaminoglycan (GAG) profiling in subjects first diagnosed with metastatic ccRCC is hypothesized to be useful in monitoring drug response and predict the outcome of a CT scan. To this end, regularly measured plasmatic and urinary GAGs in prospectively enrolled subjects will be correlated to drug response as ...

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Multicenter Study of Immunoadsorption in Dilated Cardiomyopathy

Dilated cardiomyopathy (DCM) is characterized by ventricular chamber enlargement and systolic dysfunction with normal LV wall thickness. According to reports heretofore, the incidence of this disorder in industrialized Western countries lies within the order of magnitude of 5 - 8 new illnesses per year for every 100,000 population. The prevalence, ...

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Molecular Markers in Treatment in Endometrial Cancer

This is a prospective multicenter study to investigate the predictive value of molecular markers in endometrial cancer for lymph node metastasis, prognosis and treatment. For the previously studied tumor markers p53, p16, ER, PR and HER2neu, we want to investigate the expression in curettage material in relation to lymph node ...

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A Prospective Randomized Multicentre Study to Compare Crinone 8% Once Daily Versus Other Vaginal Progesterone.

To compare the effect of Crinone 8% administered once daily versus other vaginal progesterone in terms of ongoing pregnancy rate 5 weeks after embryo transfer as well as patient convenience.

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Efficacy and Safety of Nilotinib Patients With Newly Diagnosed CML - CP (Chronic Myelogenous Leukemia - Chronic Phase)

This study will evaluate the safety and tolerability of nilotinib after failure of imatinib therapy or imatinib therapy after nilotinib failure.

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Optimal Coronary Flow After PCI for Myocardial Infarction - a Pilot Study

After coronary stenting, index of microvascular resistance (IMR) will be measured invasively. Patients with IMR >30 will be randomised to 20 mg alteplase or placebo (NaCl) administered in the culprit vessel through a microcatheter. Magnet resonance imaging (MRI) of the myocardium will be performed early (2-6 days) and late (3 ...

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Hyperbaric Oxygen Treatment of Mandibular Osteoradionecrosis. A Randomized Clinical Study

1. Study objective The objective of the study is to evaluate the effect of hyperbaric oxygen (HBO) on mandibular osteoradionecrosis as an adjunctive to surgical treatment in patients previously irradiated for head and neck cancer. Hypothesis: Osteoradionecrosis lesions heal more frequently when administering HBO as an adjunct to surgery. 2. ...

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Effects of Antirheumatic Treatment on Levels of Survivin in Rheumatoid Arthritis Patients

In a prospective observational study the investigators aim to study the ability of modern antirheumatic treatments to suppress levels of survivin in sera. Rheumatoid arthritis patients scheduled to start new pharmacological treatment will be followed for a period of 6 months. No intervention or influence on choice of treatment will ...

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