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Den Haag, Netherlands Clinical Trials

A listing of Den Haag, Netherlands clinical trials actively recruiting patients volunteers.

RESULTS

Found (154) clinical trials

Dislocated Stable Distal Both-Bone Forearm Fractures in Children

children who arrive at the emergency unit with a dislocated both-bone distal forearm fracture will be asked to join the trial. After informed consent, a randomization between 2 kinds of treatment will be done: K-wire fixation or no K-wire fixation of the fracture after a stable reposition. Outpatient clinic visits ...

Phase N/A

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Undislocated Distal Both-Bone Forearm Fractures in Children

children who arrive at the emergency unit with a undislocated both-bone distal forearm fracture will be asked to join the trial. After informed consent, a randomization between 2 kinds of cast will be done. Outpatient clinic visits till a follow-up of 6 months. During these visits we will investigate: consolidation ...

Phase N/A

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Treatment of Stable Both-Bone Midshaft Forearm Fractures in Children

children who arrive at the emergency unit with a stable both-bone midshaft forearm fracture will be asked to join the trial. If the fracture will be stable during reposition in the operating room, a randomization between 2 kinds of plaster treatment will be done. Outpatient clinic visits till a follow-up ...

Phase N/A

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Dislocated Unstable Distal Both-Bone Forearm Fractures in Children

children who arrive at the emergency unit with a dislocated both-bone distal forearm fracture will be asked to join the trial. After an unstable reposition, the fracture will be fixated with 2 Kirschner-wires. The arm will be immobilised in above elbow cast during 4 weeks. Outpatient clinic visits till a ...

Phase N/A

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Pre-operative Hormonal Treatment for Hormone Receptor Positive Breast Cancer

We will perform a randomized, open-label, single-institution study. It will compare the efficacy of three different endocrine treatment regimens (Anastrozole +/- Fulvestrant or Tamoxifen) in changing proliferation-index and inducing apoptosis during a 2-6 week pre-operative treatment period in breast cancer patients. These results will be correlated to gene expression profiles, ...

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2nd Line Erlotinib Treatment With (Out) Chemotherapy of Advanced Non Small Cell Lung Cancer (NSCLC)

Open randomized multicenter phase II study in patiënts in need of 2nd line treatment for advanced/metastatic NSCLC. Efficacy and safety of monotherapy with erlotinib will be compared with combination therapy of erlotinib and chemotherapy. In recent studies it was established that pemetrexed activity is more pronounced in non-squamous NSCLC in ...

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The Dutch Acute Stroke Trial (DUST): Prediction of Outcome With Computed Tomography (CT) - Perfusion and CT-angiography

Less than 10% of all ischemic stroke patients are treated by intravenous thrombolysis (IVT) as most present later than the accepted 3 hour time window. Intra-arterial thrombolysis (IAT) is possible 3-6 hours post ictus, but is infrequently used. Mechanical thrombectomy (MT) with a MERCI device is a new intervention possibility ...

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The Efficacy of a Cognitive-Behavioural Intervention in Deliberate Self-Harm Patients

1. The development of treatment interventions for non-fatal deliberate self-harm (DSH) among young people has received little attention in scientific literature and in mental health care. This is surprising, considering the relatively high rates of hospital-referred DSH among adolescents reported in epidemiological studies (Arensman et al., 1995; Hawton et al., ...

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REstricted Versus Liberal Positive End-Expiratory Pressure in Patients Without ARDS

Research question: Is mechanical ventilation with the lowest possible PEEP level, as compared to mechanical ventilation with the PEEP level currently practiced, non inferior in terms of the number of ventilator-free days at days 28 in patients without ARDS? Study design: National multicenter, non-inferiority, open randomized controlled trial in intubated ...

Phase N/A

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Cabazitaxel in mCRPC Patients With AR-V7 Positive Circulating Tumor Cells (CTCs)

After failure on docetaxel, which has been the standard first line therapy for patients with metastatic castration-resistant prostate cancer (mCRPC), several treatment options are currently available. Two of the treatment options are directed against the androgen receptor (AR), enzalutamide and abiraterone. A third option is cabazitaxel, a next generation taxane. ...

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