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Kisumu, Kenya Clinical Trials

A listing of Kisumu, Kenya clinical trials actively recruiting patients volunteers.

RESULTS

Found (22) clinical trials

A Surveillance Study of Diseases Specified as Adverse Events of Special Interest of Other Adverse Events Leading to Hospitalisation or Death and of Meningitis in Children in Africa Prior to Implementation of the RTS S/AS01E Candidate

The outcomes of interest (AESI, other AE leading to hospitalization or death, and meningitis) as well as data on malaria morbidity and mortality will be captured through active and enhanced hospitalization surveillance in children < 5 years of age. Children enrolled in active surveillance will be visited at their home ...

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An Epidemiology Study of Malaria Transmission Intensity in Children in Sub-Saharan Africa

Nine annual cross sectional surveys at peak transmission will provide point estimates of parasite prevalence and subsequently a longitudinal assessment of the level of endemicity in each area covered by EPI-MAL-002 and EPI-MAL-003. This study will be conducted in parallel to EPI-MAL-002 and EPI-MAL-003 in order to assess parasite prevalence ...

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Malaria Transmission and Immunity in Highland Kenya

The purpose of this study is to see why malaria epidemics occur in highland areas in Kenya. A better understanding of factors contributing to malaria may be necessary for malaria vaccine planning. These factors include interactions between age, where malaria is passed from mosquitoes to people, immune system (how the ...

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TBTC Study 31: Rifapentine-containing Tuberculosis Treatment Shortening Regimens

Title Rifapentine-containing treatment shortening regimens for pulmonary tuberculosis: a randomized, open-label, controlled, phase 3 clinical trial Hypotheses Seventeen (17) week rifapentine-based regimen In previously untreated individuals with active drug-susceptible pulmonary tuberculosis treated with eight weeks of rifapentine (P), isoniazid (H), pyrazinamide (Z) and ethambutol (E) followed by nine weeks of ...

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Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection in Women

This study will evaluate the safety, tolerability, and efficacy of the VRC01 antibody in preventing HIV-1 infection in healthy women at high risk of HIV infection. Participants will be enrolled from a cohort of heterosexual women in sub-Saharan Africa. An equal number of study participants will be randomized to receive ...

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Prospective Study of Lopinavir Based ART for HIV Infected childreN Globally (LIVING Study)

The primary objective is to evaluate the effectiveness of LPV/r pellets in addition to AZT/3TC (or ABC/3TC) paediatric fixed dose combination (FDCs) tablet under routine treatment conditions in HIV infected infants and young children who cannot swallow tablets. As secondary objectives: Document the safety of LPV/r pellets and AZT/3TC or ...

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Brief Bactericidal Activity of Anti-Tuberculosis Drugs

Multidrug-resistant (MDR) tuberculosis (TB) must be treated with second-line drugs (SLD) that are less effective, more toxic, and more expensive. Treatment requires at least 20 months with 4 or more effective drugs based on timely drug susceptibility test (DST) results. However, there are many examples of closely related drugs with ...

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An Adaptive Strategy for Preventing and Treating Lapses of Retention in Adult HIV Care (AdaPT-R) in Nyanza Kenya

Retaining HIV-infected patients in care is critical, but loss to follow-up after enrolment often reaches 20%-40% by two years, placing millions of patients at risk of poor outcomes. A strategy to optimize retention within resource constraints is urgently needed. Sequential adaptive strategies - a novel class of public health approaches ...

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Three Chemo Regimens as an Adjunct to ART for Treatment of Advanced AIDS-KS

This study is being done to compare the safety and efficacy of three combination treatments for Kaposi's Sarcoma and AIDS.

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