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Neuss, Germany Clinical Trials

A listing of Neuss, Germany clinical trials actively recruiting patients volunteers.

RESULTS

Found (234) clinical trials

A Study of LY900014 in Elderly and Younger Adult Participants With Type 1 Diabetes Mellitus

The purpose of this study is to compare LY900014 with insulin lispro in elderly and younger adults with type 1 diabetes mellitus. Screening is required within 28 days prior to the start of the study. For each participant, the total duration of the clinical trial will be between 3 to ...

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A Trial to Investigate the Dose-linearity of BioChaperone Combo 75/25 and the Safety at Three Different Doses in Subjects With Type 2 Diabetes

This is a bicentric, double-blinded, randomised, four-period crossover phase 1 trial, using automated 30-hour euglycemic clamp in subjects with type 2 diabetes mellitus. Each subject will be randomly allocated to a sequence of four treatments, three single doses of BioChaperone® Combo 75/25 (0.6 U/kg, 0.8 U/kg or 1.0 U/kg) and ...

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A Trial to Investigate Pharmacokinetics Pharmacodynamics Safety and Tolerability of BioChaperone Pramlintide Insulin in Patients With Type 1 Diabetes Mellitus

This is a single center, randomised, double-blind, active comparator controlled, three-period cross-over, single dose trial in subjects with type 1 diabetes mellitus. Each subject will be randomly allocated to a sequence of three treatments:(i) simultaneous administrations of BioChaperone pramlintide human insulin (BC Pram Ins) and placebo, (ii) simultaneous injections of ...

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OPTIMAL>60 / DR. CHOP Improvement of Therapy of Elderly Patients With CD20+ DLBCL Using Rituximab Optimized and Liposomal Vincristine

Primary objective of study: "OPTIMAL>60 Less Favourable" Patients with less favourable prognosis: To test whether progression-free survival (PFS) can be improved by substituting conventional by liposomal vincristine; To test whether PFS can be improved by 12 optimised applications instead of 8 2-week applications of rituximab. "OPTIMAL>60 Favourable": Patients with favourable ...

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A Study of Glucagon Nasal Powder in Participants With Type 1 Diabetes Mellitus

The purpose of this study is to compare a needle-free treatment of hypoglycemia with glucagon nasal powder (study drug) to a marketed glucagon administered by the intra-muscular (IM) route, in participants with type 1 diabetes mellitus (T1DM).

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A Trial to Investigate the Safety and the Pharmacokinetic Pharmacodynamic Characteristics of Two BioChaperone Glucagon Formulations Compared to Marketed GlucaGen in Subjects With T1DM

This is a single centre, double-blind, randomised, three-period crossover phase 1 trial in subjects with type 1 diabetes mellitus (T1DM). Each subject will be randomly allocated to a sequence of three treatments, i.e. two single subcutaneous doses of BioChaperone® Glucagon (BC Glucagon) formulation 1, BioChaperone® Glucagon formulation 2 and GlucaGen® ...

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0.83 miles

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A Trial to Evaluate the Pharmacokinetic and Pharmacodynamic Properties of BioChaperone Insulin Lispro Fiasp and NovoRapid Delivered by an Insulin Pump

This is a single-centre, randomised, double-blind, three-period, complete cross-over trial comparing the pharmacokinetic and the pharmacodynamic properties of BioChaperone® insulin lispro and the two active comparators Fiasp® and Novorapid® when given as a bolus on top of basal delivery with an insulin pump in subjects with type 1 diabetes mellitus. ...

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0.83 miles

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A Study to Investigate Different Doses of 0382 in Overweight and Obese Subjects With Type 2 Diabetes Mellitus.

This is a randomised, double-blind, placebo-controlled study designed to evaluate the efficacy, safety, tolerability, and pharmacokinetics of different doses of MEDI0382 administered as multiple SC doses to subjects with T2DM. Approximately 63 subjects will be enrolled across two cohorts. For cohort 1, sufficient subjects will be invited to participate in ...

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0.83 miles

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A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique in Patients With Type 1 Diabetes Mellitus

The study duration per patient will be 18 to 62 days and will consist of a 4 to 28 days of screening period, a treatment period of 2 days, a washout between dosing occasions of 5-18 days, and follow up visit 7-14 days after last dosing.

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0.83 miles

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A Study of LY3209590 in Healthy Participants and Participants With Type 2 Diabetes

This trial is conducted to evaluate the safety of a study drug given by injection under the skin to healthy participants and participants with type 2 diabetes. It will also investigate how the body processes the study drug and the effect of the study drug on blood sugar levels. Information ...

Phase

0.83 miles

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