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Villejuif Cedex, France Clinical Trials

A listing of Villejuif Cedex, France clinical trials actively recruiting patients volunteers.

RESULTS

Found (15) clinical trials

Durvalumab Plus Tremelimumab Combination Immunotherapy With or Without Weekly Paclitaxel in Patients With Advanced Biliary Tract Carcinoma (BTC) After Failure of Platinum-based Chemotherapy

Biliary tract carcinoma (BTC, adenocarcinoma in more than 90% of cases) is the second primary liver tumor in incidence after hepatocellular carcinoma (2,000 new cases/year in France). The prognosis of biliary malignancies is poor, with a 5-year overall survival rate (OS) of about 10-15%, most often due to late diagnosis, ...

Phase

0.0 miles

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Exploration of Dyspnea at Non-high Brain Natriuretic Peptide (BNP)

Patients with unexplained stress dyspnea ( stage 2 NYHA), no significant underlying lung disease, with an ejection fraction > 50%, normal resting filling pressures, NTproBNP < 220 pg/ml in < 75 years, and < 450 pg/ml in 75 years will be studied with stress echocardiography and cardiometabolic stress test (VO2). ...

Phase N/A

1.09 miles

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Follow up Study to Assess Long Term Safety and Outcomes in Infants and Children Born to Mothers Participating in Retosiban Treatment Studies

The primary objective of this study is to assess the safety and outcomes of infants and children who were exposed to retosiban or comparator in utero in the planned Phase III spontaneous preterm labor (SPTL) treatment studies, to provide assurance that treatment is not associated with significant adverse outcomes in ...

Phase

1.21 miles

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Study of the Thoraflex Hybrid Device for the Treatment of Aneurysm/Dissection of the Descending Thoracic Aorta

Quality control will be performed continuously at various stages of the error correction process, according to the sponsor's Standard Operating Procedures. Systematic coherence control procedures will be implemented and documented. The correction procedures will be tracked. For the study data, requests (Queries) will be issued and transmitted to the various ...

Phase N/A

2.63 miles

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Study of Left Ventricular Function of Patients With Type 2 Diabetes Without Cardiovascular Disease

The main objective of this study is to analyze left ventricular function by echocardiography in a prospective cohort of 200 patients with type 2 diabetes and without known cardiac dysfunction and to search for possible differences in clinical profile depending on the presence and type of cardiac function's impairment. Patients ...

Phase N/A

3.08 miles

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Study of Telisotuzumab Vedotin (ABBV-399) in Subjects With Previously Treated c-Met+ Non-Small Cell Lung Cancer

This study is designed to identify the target Non-Small Cell Lung Cancer (NSCLC) population(s) that over express c-Met (c-Met+) best suited for telisotuzumab vedotin therapy in the second line or third line setting (Stage 1) and then to expand the group(s) to further evaluate efficacy in the selected population(s) (Stage ...

Phase

3.59 miles

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Molecular Diagnosis of Respiratory Viral Infections on Sputum From Cystic Fibrosis Patients

Viral respiratory infections in cystic fibrosis (CF) have a significant impact on the progression of the disease. It is therefore essential to look for these viruses. No recommendations are made for the virological follow-up of CF patients and no optimal strategy for the type of sampling required. In non-CF patients, ...

Phase N/A

3.97 miles

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Treatment of Breast Fibroadenoma With High Intensity Focused Ultrasound (HIFU)

Fibroadenomas are well-circumscribed benign tumors, easily distinguishable from adjacent normal breast tissue on ultrasound images. The goal of this protocol is to compare HIFU and surgery in terms of cost, safety, and clinical effectiveness for the treatment of nonmalignant breast tumors. Fibroadenomas appear to be an ideal target for evaluation ...

Phase N/A

3.97 miles

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Impact of a PCT(Procalcitonin) Rapid Test -Based Approach on ATB (Antibiotics) Use in Children With Fever Without Source

This prospective multicentric randomized study will include 7500 febrile children aged six days to three years, diagnosed with fever without source, in 22 participating French and Swiss emergency departments, during a 12-month period. During one period, all children will receive usual care. In a second period, the DIAFEVER algorithm will ...

Phase N/A

4.39 miles

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A Study of Nivolumab Combined With Ipilimumab and Nivolumab Alone in Patients With Advanced or Metastatic Solid Tumors of High Tumor Mutational Burden (TMB-H)

The purpose of this study is to determine whether nivolumab plus ipilimumab or nivolumab alone is effective and safe in the treatment of solid tumors with High Tumor Mutational Burden (TMB-H)

Phase

4.43 miles

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