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London, Denmark Clinical Trials

A listing of London, Denmark clinical trials actively recruiting patients volunteers.

RESULTS

Found (15) clinical trials

A Phase I/II Study of MEDI4736 in Combination With Olaparib in Patients With Advanced Solid Tumors.

This is a phase I/II open-label, multicenter study to evaluate the safety, tolerability, pharmacokinetics (PK) and antitumor activity of MEDI4736 in combination with olaparib in patients with advanced solid tumors, selected based on a rationale for response to olaparib. Patients will be poly (adenosine diphosphate-ribose) polymerase (PARP)-inhibitor and immunotherapy (IMT)-nave ...

Phase

0.75 miles

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Treatment-Resistant Depression Cohort in Europe

This TRD cohort study will collect critically important data from routine clinical practice in Europe which will further substantiate the understanding of TRD in European clinical practice, with the aim of improving guidance and informing the development of better treatment strategies for this medically important condition. All data recorded in ...

Phase N/A

1.43 miles

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Participant-Reported Outcomes With the Accu-Chek Solo Micropump System

This interventional device study aims to compare mainly standard Multiple Dose Injection (MDI) therapy vs. Accu-Chek Solo Micropump System and investigates participant satisfaction. In addition, a third arm is included to compare to only similar product on the market which is OmniPod. The third arm is for data collection purpose.

Phase N/A

1.47 miles

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HepCare: The Effectiveness of Community Based Interventions With Peer Support to Improve Case Detection Carry Out Pre-treatment Assessments and Assist Underserved Populations Through HCV Treatment

Introduction Hepatitis C infection is a major cause of chronic liver disease and death throughout the world1. Approximately 3% of the world's population is infected with hepatitis C virus (HCV)2. HCV is transmitted by blood and in the UK occurs primarily through injecting drug use. Chronically infected people are at ...

Phase N/A

2.0 miles

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Postprandial Responses to Typical UK Meal Nutrient Profiles

Background: Dietary fat consumption is one of the major modifiable risk factors implicated in the causation of cardiovascular disease (CVD). Postprandial lipaemia (PPL) the increase in circulating blood triacylglycerol (TAG) concentrations after a fat containing meal, is an independent risk factor for cardiovascular disease. However, little is known about how ...

Phase N/A

2.22 miles

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Study in Huntington's Disease Patients Who Participated in Prior Investigational Studies of ISIS 443139

This study will test the safety, tolerability, pharmacokinetics and pharmacodynamics of IONIS-HTTRx administered intrathecally to adult patients with Huntington's Disease.

Phase

2.32 miles

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Healthy Eating & Active Lifestyles for Diabetes: Feasibility Trial

This study is a feasibility trial with an embedded process evaluation of the HEAL-D intervention compared with usual care. The study will use a randomised controlled trial (RCT) design, with individual patients as the unit of randomisation, evaluating the HEAL-D programme against usual care. The RCT design has been chosen ...

Phase N/A

3.07 miles

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Radiofrequency Endoscopic Ablation With Ultrasound Guidance: a Non-surgical Treatment for Aldosterone-producing Adenomas

Primary hyperaldosteronism (PA) is one of the commonest causes of hypertension. It is estimated to be the root cause in 10% of all patients with hypertension and 20% of all patients with resistant hypertension. Conventionally, patients with PA are divided 50:50 into those with a curable, unilateral aldosterone-producing adenoma (APA), ...

Phase N/A

3.07 miles

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Developing and Validating Blood and Imaging BIOmarkers of AXonal Injury Following Traumatic Brain Injury

Traumatic brain injury (TBI) occurs when the brain is physically damaged, for example after a car crash. It is common and survivors often have major on-going problems. It is very difficult to predict how patients will do after TBI. One reason for this is that clinicians and researchers are unable ...

Phase N/A

3.51 miles

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Self-management Intervention to Improve Adolescents' Asthma Control

We have developed a theory-driven self-management intervention for children and young people which addresses the barriers to successful self-management, which were identified in our earlier study. The intervention will engage asthmatic teenagers and their peers, and will be delivered in two components. The first component includes a theatre workshop for ...

Phase N/A

4.38 miles

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