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Malvern East, Australia Clinical Trials

A listing of Malvern East, Australia clinical trials actively recruiting patients volunteers.


Found (5) clinical trials

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

Pre-specified primary analysis for Aim 1 is the change in AHI with combination treatment versus oral appliance alone (%reduction versus placebo; including hypopnea events without desaturation/arousals). Aim 2 seeks to identify subgroups of patients that have the greatest reduction in AHI (responders) with each treatment (post-hoc). We will use baseline ...


5.04 miles

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First in Human Study in Healthy Volunteers Followed With Dosing in Participants With Lung or Liver Fibrosis

First in Human single ascending dose followed by multiple ascending doses in healthy volunteers followed by multi dose in participants with lung or liver fibrosis.


5.45 miles

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Study to Assess the Efficacy and Safety of ACT-541468 in Adult and Elderly Subjects With Insomnia Disorder

The main purpose of this study is to assess efficacy and safety of ACT-541468 in subjects with insomnia disorder. Efficacy will be evaluated on sleep onset and sleep maintenance.


6.09 miles

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A Study of Atezolizumab in Combination With Nab-Paclitaxel Compared With Placebo With Nab-Paclitaxel for Participants With Previously Untreated Metastatic Triple-Negative Breast Cancer (IMpassion130)

This multicenter, randomized, double-blind study will evaluate the efficacy, safety, and pharmacokinetics of atezolizumab (MPDL3280A) administered with nab-paclitaxel compared with placebo in combination with nab-paclitaxel in participants with locally advanced or metastatic triple-negative breast cancer (TNBC) who have not received prior systemic therapy for metastatic breast cancer (mBC). The safety ...


6.8 miles

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International Observational Study on Perioperative Cognitive Trajectories (POCD Census International/PCI)

This international observational study on perioperative cognitive trajectories (POCD census international/PCI) has been designed as a pilot study to allow a peer reviewed process of four international test centres on measurement of perioperative acute and long-term cognitive outcome. Data from standard clinical treatment of 500 patients age 70 years scheduled ...

Phase N/A

7.06 miles

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