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Clinical Trial Details


Research Study Summary

Patients are needed to participate in a clinical research study of caspofungin to evaluate Invasive Pulmonary Aspergillosis or Chronic Obstructive Pulmonary Disease

Research Study Title

Prospective, Open-label Study of the Efficacy and Safety of Caspofungin for the Treatment of Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease


The investigators propose to study the efficacy and safety of three-week antifungal therapy with caspofungin in hospitalized patients with proven or probable IPA underlying chronic obstructive pulmonary disease.

To Learn more



Both Male and Female


18 and up

Overall Status


Lead Sponsor

The First Affiliated Hospital of Guangzhou Medical University


32 Months

Facility Type



Both Male and Female ages 18 Years and up

Inclusion Criteria:

  • Proven invasive pulmonary aspergillosis

  • Probable invasive pulmonary aspergillosis

  • Hospitalized in respiratory wards

  • Not having received an empirical antifungal therapy for 72h before inclusion

Exclusion Criteria:

  • A history of allergy to echinocandins

  • Severe renal failure, severe hepatic insufficiency

  • Inadequately treated bacterial infection

  • Documented HIV infection

  • Status of pregnancy or lactation

Site Locations (1)

Country State City Zip Facility and Contact
China Guangdong Guangzhou 510120 Guangzhou Institute of Respiratory Diseases
Nanshan Zhong, MD

Feng Ye, MD
Principal Investigator


Feng Ye, MD

NCT ID: NCT01499433

Date Last Changed: January 22, 2014

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