Research Study Summary
A clinical trial to evaluate treatments using tricuspid isthmus imaging with Cartosound for patients with Atrial Flutter
Research Study Title
Tricuspid Isthmus Architecture as Imaged by CARTOsound, Determines Ablation Times in Patients With Typical Atrial Flutter
The investigators propose a third hypothesis based on the anatomic observations made in
pathological studies. The investigators hypothesize that the anatomic architecture
determines the functional properties of the TV-IVC isthmus. As a result,
• Muscular bundles are preferential routes of conduction through the TV-IVC isthmus. The
isthmus acts like a series of discreet conduction routes rather than as a sheet of tissue.
The muscular bundles form selective targets for ablation and therefore the entire anatomic
line need not be ablated. This has direct implications for ablation of the isthmus.
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