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Clinical Trial Details


Research Study Summary

A clinical trial to evaluate treatments using tricuspid isthmus imaging with Cartosound for patients with Atrial Flutter

Research Study Title

Tricuspid Isthmus Architecture as Imaged by CARTOsound, Determines Ablation Times in Patients With Typical Atrial Flutter


The investigators propose a third hypothesis based on the anatomic observations made in pathological studies. The investigators hypothesize that the anatomic architecture determines the functional properties of the TV-IVC isthmus. As a result,

• Muscular bundles are preferential routes of conduction through the TV-IVC isthmus. The isthmus acts like a series of discreet conduction routes rather than as a sheet of tissue.

The muscular bundles form selective targets for ablation and therefore the entire anatomic line need not be ablated. This has direct implications for ablation of the isthmus.

To Learn more

Both Male and Female


18 and up

Overall Status


Lead Sponsor

Lawson Health Research Institute


9 Months

Facility Type



Both Male and Female ages 18 Years and up

Inclusion Criteria:

  • Patients must be over 18 years of age provided written informed consent documented atrial flutter by ECG , holter monitor or TTM

Exclusion Criteria:

  • previous atrial flutter ablation non isthmus dependent atrial flutter prior right atrial surgery

Site Locations (1)

Country State City Zip Facility and Contact
Canada Ontario London N6A 5A5 London Health Sciences Center


Allan Skanes, MD

NCT ID: NCT01113788

Date Last Changed: April 29, 2010

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