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Clinical Trial Details


Research Study Summary

A clinical trial to evaluate treatments using donepezil for patients with Alzheimer's Disease or Dementia

Research Study Title

Comparative Assessment of Clinical Efficacy of Donepezil Between the Patients With Alzheimer's Disease and Mixed Dementia


To compare the clinical efficacy of donepezil between patients with Alzheimer's disease and Mixed Dementia.

To Learn more

Both Male and Female



Overall Status


Lead Sponsor

Samsung Medical Center


69 Months

Facility Type



Both Male and Female ages up to N/A

Inclusion Criteria:

  1. A diagnosis of probable AD and Mixed Dementia according to the criteria of the NINCDS-ADRDA

  2. Korean version Mini-Mental State Examination scores between 10 and 26

  3. History of cognitive decline that had been gradual in onset and progressive over at least 6 months

  4. A caregiver who could assist the patient with medication, attend the assessment and provide information about the patient.

Exclusion Criteria:

  1. they had evidence of any neurodegenerative diseases other than AD (i.e. Parkinson's disease, Huntington's disease)

  2. Psychiatric disorder or severe behavioral disturbances that required psychotropic medications

  3. Cerebral injuries induced by trauma, hypoxia, and/or ischemia

  4. Clinically active cerebrovascular disease; History of seizure disorder

  5. Other physical conditions that required acute treatment.

Site Locations (1)

Country State City Zip Facility and Contact
Korea, Republic of Seoul City 135-710 Samsung Medical Center
DohKwan Kim, M.D.,Ph.D.


Doh Kwan Kim, PhD., M.D.

NCT ID: NCT01023867

Date Last Changed: June 26, 2012

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