Clinical Trial Details

NCT ID: NCT01023867
Date Last Changed: June 26, 2012


Research Study Summary

A clinical trial to evaluate treatments using donepezil for patients with Alzheimer's Disease or Dementia

Research Study Title

Comparative Assessment of Clinical Efficacy of Donepezil Between the Patients With Alzheimer's Disease and Mixed Dementia


To compare the clinical efficacy of donepezil between patients with Alzheimer's disease and Mixed Dementia.

To Learn more

Recruitment Details

Both Male and Female
Overall Status
Lead Sponsor
Samsung Medical Center
69 Months
Facility Type


Both Male and Female ages up to N/A

Inclusion Criteria:

  1. A diagnosis of probable AD and Mixed Dementia according to the criteria of the NINCDS-ADRDA

  2. Korean version Mini-Mental State Examination scores between 10 and 26

  3. History of cognitive decline that had been gradual in onset and progressive over at least 6 months

  4. A caregiver who could assist the patient with medication, attend the assessment and provide information about the patient.

Exclusion Criteria:

  1. they had evidence of any neurodegenerative diseases other than AD (i.e. Parkinson's disease, Huntington's disease)

  2. Psychiatric disorder or severe behavioral disturbances that required psychotropic medications

  3. Cerebral injuries induced by trauma, hypoxia, and/or ischemia

  4. Clinically active cerebrovascular disease; History of seizure disorder

  5. Other physical conditions that required acute treatment.

Site Locations (1)

Country State City Zip Facility and Contact
Korea, Republic of Seoul City 135-710 Samsung Medical Center
DohKwan Kim, M.D.,Ph.D.


Doh Kwan Kim, PhD., M.D.

DISCLAIMER: CenterWatch does not conduct clinical research. CenterWatch is a publishing company that posts clinical trials information on behalf of sponsor companies, contract research organizations, clinical research sites and other interested parties. This information is designed to help patients find clinical trials of interest and contact the research centers conducting the trials.