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Home > About MS > Clinical Trials Resource Center

Location » Texas » Houston

Clinical Trial Details

Overview

Research Study Summary

A clinical trial seeking patients for a research study for the treatment of Stroke, Myocardial Infarction or Diabetes

Research Study Title

Insulin Resistance Intervention After Stroke (IRIS) Trial

Purpose

The purpose of this study is to determine if pioglitazone is effective in preventing future strokes or heart attacks among non-diabetic persons who have had a recent ischemic stroke.

To Learn more
Phase

3

Gender

Both Male and Female

Age

40 and up

Overall Status

Recruiting

Lead Sponsor

Yale University

Duration

123 Months

Facility Type

N/A

Eligibility

Both Male and Female ages 40 Years and up

Inclusion Criteria

  1. Ages 40 years or greater at the time of randomization.

  2. Ischemic stroke or TIA no less than 14 days and no more than 6 months before randomization

  3. Documentation of insulin resistance as defined by a value over 3.0 on the Homeostasis Model Assessment of insulin sensitivity (HOMA).

  4. Both ability and willingness to provide informed consent.

  5. Presence of none of the exclusion criteria.

Exclusion Criteria

Permanent Exclusions

  1. Severely disabling stroke as indicated by an inability to participate in scheduled follow-up activities.

  2. Persons whose ischemic stroke or TIA was related to structural cardiac lesion, significant head trauma, proximal arterial dissection or medical instrumentation.

  3. Diabetes mellitus as defined by recent use of medication for diabetes as an out-patient (*see note below) or two fasting plasma blood sugars > 126 mg/dL.

  4. HgbA1c > 7.0%.

  5. Irreversible medical conditions likely to affect short-term survival or ability to participate in the study protocol. These include:

  6. Cancer or other chronic disease with poor prognosis (predicted survival of less than four years).

  7. Severe neurologic or psychiatric disease that would complicate the evaluation of study outcomes (e.g., dementia or schizophrenia).

  8. History of intolerance to any thiazolidinedione.

  9. Pregnancy or desire to become pregnant.

  10. Oral contraceptive use.

  11. Ongoing use of oral corticosteroids.

  12. History of heart failure

  13. Active liver disease as defined by known liver disease accompanied by cirrhosis, significant cholestasis, portal hypertension, hepatic encephalopathy, hepatic synthetic dysfunction, or expected significant loss of liver function over the course of the study.

  14. History of bladder cancer.

  15. Current participation in a conflicting clinical trial. A conflicting clinical trial is defined as a trial with any of following:

  16. Intervention that is known to affect the incidence of stroke or myocardial infarction.

  17. Intervention that is an experimental drug.

  18. Outcome that includes stroke or myocardial infarction.

  19. Exclusion for participation in another trial.

Temporary Exclusions Persons with temporary exclusions may be enrolled as soon as the exclusion has resolved.

  1. ALT > 2.5 times the upper limit of normal.

  2. Hemoglobin < 8.5 g/dl.

  3. Moderate or severe pitting edema of the feet or legs (IRIS grade 3 or 4).

  4. Carotid surgery or carotid stenting procedure scheduled (delay randomization until 2 weeks following procedure).

Site Locations (160)

Country State City Zip Facility and Contact
United States Alabama Mobile 36617-2293 University of South Alabama
Mel Parnell
251-471-7338
mparnell@usouthal.edu

Richard M. Zweifler, MD
Principal Investigator
United States Arizona Tucson 85721-5023 University of Arizona
Mina Malekniazi
520-626-4150
stroke@neurology.arizona.edu

Bruce M. Coull, MD
Principal Investigator
United States California Fresno 93702 UCSF-Fresno
Rebekah Rau
559-459-3845
rrau@fresno.ucsf.edu

Michael Peterson, MD
Principal Investigator
United States California La Jolla 92037 Scripps Clinic
Crystal Sanchez
858-652-5440
sanchez.crystal@scrippshealth.org

Christy Jackson, MD
Principal Investigator
United States California Los Angeles 90033 University of Southern California
Ana Pardo
323-226-7381
apardo@lacusc.org

Gene Yoi, MD
Principal Investigator
United States California Palo Alto 94304 Stanford University
Madelleine Garcia
650-725-2326
magarcia@stanford.edu

Maarten Lansberg, MD
Principal Investigator
United States California Sacramento 95817 University of California-Davis
Katrina Belova
916-734-6697
katrina.belova@udcmc.ucdavis.edu

Piero Verro, MD
Principal Investigator
United States California San Diego 92103-8466 University of California
Nancy Kelly
858-657-7181
nkelly@ucsd.edu

Brett Meyer, MD
Principal Investigator
United States California San Francisco 94143-0114 University of California
Terry Yi
415-514-2120
theresa.yi@ucsfmedctr.org

S. Clairborne Johnston, MD
Principal Investigator
United States Colorado Denver 80204-4507 Denver Health and Hospital Authority
Carol Hennessy
303-436-6363
chenness@dhha.org

Richard L. Hughes, MD
Principal Investigator
United States Connecticut Hartford 06102-5037 Hartford
Jennifer Blum
860-545-1977
jjblum@harthosp.org

Isaac E. Silverman, MD
Principal Investigator
United States Connecticut New Haven 06519 Yale University
Barbara Mendes
203-764-7000
barbara.mendes@yale.edu

Walter N. Kernan, M.D.
Principal Investigator
United States Florida Gainesville 32610 University of Florida
Elizabeth Brooks
352-273-5551
Elizabeth.brooks@neurology.ufl.edu

Michael Waters, MD
Principal Investigator
United States Florida Jacksonville 32209 University of Florida
Rhonda Calhoun
904-244-9815
rhona.calhoun@jax.ufl.edu

Scott Silliman, MD
Principal Investigator
United States Florida Melbourne 32901 MIMA Century Research Associates
Sharon Krubel
321-725-4500 ext. 796
sharon.krubel@mima.com

Bhuvanesware Dandapani, MD
Principal Investigator
United States Florida Tampa 33606-3500 Floria Neurovascular Institute
Stephanie Segal
813-250-9101
flneurovascular@gmail.com

Erfan Albakri, MD
Principal Investigator
United States Illinois Chicago 60612 Cook County (Stroger) Hospital
Maribeth Ohprecio
312-864-7294
maribeth.ohprecio@hektoen.org

Michael A. Kelly, MD
Principal Investigator
United States Illinois Chicago 60612 University of Illinois
Ginny Mezo
312-413-9392
vmezzo@uic.edu

Laura Pedelty, MD
Principal Investigator
United States Illinois Chicago 60612 Rush University
Susan Dvojack
312-563-2208
Susan_A_Dvojack@rush.edu

Shyam Prabhakaran, MD
Principal Investigator
United States Illinois Harvey 60426 Ingalls Memorial Hospital (NINDS-CRC site)
Deborah Lawrence
798-915-5563
delawren@ingalls.org

Engin Yilmaz, MD
Principal Investigator
United States Illinois Maywood 60153 Loyola University Medical Center
Linda Chadwick
708-216-6638
lchadwick@lumc.edu

Michael Schneck, MD
Principal Investigator
United States Illinois Peoria 61637-0001 OSF St. Francis Medical Center
Judi Beck
309-624-3240
judith.m.beck@osfhealthcare.org

David Wang, DO
Principal Investigator
United States Indiana ELkhart 46514 Indiana Medical Research
Shari Hapner
574-296-3903
shapner@elkhartclinic.com

Thomas Vidic, MD
Principal Investigator
United States Indiana Valparaiso 46383 Associates In Neurology (NINDS-CRC site)
Carol Parks
219-476-7777 ext. 128
cparks@associatesinneurology.com

Richard Strawsburg, MD
Principal Investigator
United States Iowa Des Moines 50314 Ruan Neuroscience Center/Mercy Medical Center
Janelle Gehrke
515-358-0023
jgehrke@mercydesmoines.org

Michael Jacoby, MD
Principal Investigator
United States Iowa Des Moines 50309 Iowa Health Des Moines Clinical Trials Office
Janelle Gehrke
515-241-5875
GehrkeJS@ihs.org

Todd Janus, MD
Principal Investigator
United States Iowa Iowa City 52246 University of Iowa
Jeri Sieren
319-356-8744
jeri-sieren@uiowa.edu

Enrique Leira, MD
Principal Investigator
United States Iowa Waterloo 50702 Northeast Iowa Medical Education Foundation (NINDS-CRC site)
Pamela Trenkamp
319-240-4836
ptrenkam@neimef.org

James Poock, MD
Principal Investigator
United States Kansas Wichita 67214 Via Christi Regional Medical Center
Donna Collie
316-268-6958
donna_collie@via-christi.org

As'ad Ehtisham, MD
Principal Investigator
United States Kentucky Lexington 40536-0284 University of Kentucky Research Foundation
Deborah Taylor
859-257-5560
dtay12@email.uky.edu

Creed Pettigrew, MD
Principal Investigator
United States Louisiana Shreveport 71130-3932 Louisiana State University Health Sciences Center
Erin Eaton
318-813-1452
eeaton@isuhsc.edu

Alireza Minagar, MD
Principal Investigator
United States Maine Rockport 04856 Penobscot Bay Neurology
Jane Sigsbee
207-947-2540
jsigsbee@tidewater.net

Bruce Sigsbee, MD
Principal Investigator
United States Maryland Baltimore 21287-6953 Johns Hopkins
Susan Rice
410-614-3460
smrice@jhmi.edu

Robert J. Wityk, MD
Principal Investigator
United States Maryland Baltimore 21209 Sinai Hospital of Baltimore
Kathy Birnbaum
410-610-5712
kbirnbau@lifebridgehealth.org

Adrian Goldszmidt, MD
Principal Investigator
United States Massachusetts Boston 02118 Boston University
Helena Lau
617-414-1171
hlau@bu.edu

Carlos Kase, MD
Principal Investigator
United States Massachusetts Boston 02114-2695 Massachusetts General Hospital
Donna Defilippo
617-726-0887
ddefilippo1@partners.org

Karen L. Furie, MD
Principal Investigator
United States Massachusetts Boston 02215 Beth Israel Deaconess
Sarah LaRose
617-632-8919
slarose@bidmc.harvard.edu

Sandeep Kumar, MD
Principal Investigator
United States Minnesota Robbinsdale 55426 Minneapolis Clinic of Neurology
Amy Tanner
763-520-1542
amytanner@mpls-clinic.com

Irfan Altafullah, MD
Principal Investigator
United States Missouri St. Louis 63110 Washington University
Jill Newgent
314-747-3795
newgentj@neuro.wustl.edu

Abdullah M. Nassief, MD
Principal Investigator
United States Missouri St. Louis 63220 St. Louis University
Eve Holzemer
314-977-4971
eve.holzemer@tenehealth.com

Salvatore Cruz-Flores, MD
Principal Investigator
United States Montana Billings 59101 Billings Clinic
Rbert Verdon
406-255-8476
rverdon@billingsclinic.org

Daniel Rodriguez, MD
Principal Investigator
United States Montana Great Falls 59405 Advanced Neurology Specialists
Vicky Jo Reeves
406-761-8673
vreeves@ansresearch.com

Dennis Dietrich, MD
Principal Investigator
United States Nebraska Omaha 68198 University of Nebraska
Mary Phillips
402-559-4939
mmphillips@unmc.edu

Pierre Fayad, MD
Principal Investigator
United States New Hampshire Lebanon 03756 Dartmouth Hitchcock Medical Center
Diane Church
603-650-4243
diane.l.church@hitchcock.org

Timothy Lukovits, MD
Principal Investigator
United States New Jersey Camden 08013 Cooper University Hospital
Patricia Niblack
856-968-7269
niblack@cooperhealth.edu

Thomas Mirsen, MD
Principal Investigator
United States New Jersey West Orange 07052 Kessler Medical Rehab Research Corp
Siby Varughese
973-243-6984
svarughese@kmrrec.org

Anna Barrett, MD
Principal Investigator
United States New Mexico Albuquerque 87108 University of New Mexico
JoAnn Harnar
505-256-5701
jharnar@salud.unm.edu

Glenn D. Graham, MD
Principal Investigator
United States New York Albany 12208 Albany Medical Center
Susan Rauch
518-262-6608
rauchs@mail.amc.edu

Gary Bernardini, MD
Principal Investigator
United States New York Brooklyn 11215 New York Methodist Hospital
Mervat Estafanos
201-538-8029
bastamervat@yahoo.com

Miran Salgado, MD
Principal Investigator
United States New York Brooklyn 11203 SUNY Downstate
Lorraine Thomas
718-270-1729
lorraine.thomas@downstate.edu

Daniel Rosenbaum, MD
Principal Investigator
United States New York Buffalo 14209 SUNY Buffalo
Kathleen Parkes
716-887-5548
kparkes@kaleidahealth.org

Marilou Ching, MD
Principal Investigator
United States New York Rochester 14642 University of Rochester
Justine Zentner
585-275-1204
justine_zentner@urmc.rochester.edu

W. Scott Burgin, MD
Principal Investigator
United States New York West Seneca 14224 Southtowns Neurology of WNY (NINDS-CRC site)
Janice Suto
716-712-0890
vascneurology@yahoo.com

Peterkin Lee Kwen, MD
Principal Investigator
United States New York White Plains 10605 Burke Medical Research Institute
Rosanne Cirio
914-597-2476
rcirio@burke.org

Pasquale Fonzetti, MD
Principal Investigator
United States North Carolina Winston-Salem 27103 Clinical Research of Winston-Salem
Peggy Williams
336-287-5306
pw@triad.rr.com

Andreas Runheim, MD
Principal Investigator
United States North Carolina Winston-Salem 27103 Guilford Neurologic Associates
Pat Henderson
336-273-2511 ext. 138
phenderson@guilfordneurologic.com

Pramodkumar Sethi, MD
Principal Investigator
United States North Dakota Grand Forks 58201 Altru Health System
Renee Hendrickson
701-780-1694
rhendrickson@altru.org

Matthew Roller, MD
Principal Investigator
United States Ohio Cincinnati 45267-0525 University of Cincinnati
Jenny Osborne
513-558-4241
jennifer.osborne@uc.edu

Dawn Kleindorfer, MD
Principal Investigator
United States Ohio Cleveland 44106-4938 Case Western Reserve University
David Korosec
216-844-1800
david.korosec@uhhospitals.org

Sophia Sundararajan, MD
Principal Investigator
United States Ohio Cleveland 44195 Cleveland Clinic Foundation
Donna Prots
216-445-4488
protsd@ccf.org

Irene Katzan, MD
Principal Investigator
United States Ohio Cleveland 44109-1998 Metrohealth Medical Center
Dana Cook
216-778-7478
dcook@metrohealth.org

Joseph P. Hanna, MD
Principal Investigator
United States Ohio Columbus 43210 Ohio State University
Peggy Notestine
614-293-4975
notestine.11@osu.edu

Andrew Slivka, MD
Principal Investigator
United States Ohio Toledo 43614 University of Toledo
Andrea Korsnack
419-383-3801
akorsnack@meduohio.edu

Gretchen Tietjen, MD
Principal Investigator
United States Oregon Portland 97239-3098 Oregon Health & Science University
Corrie Doyle
503-494-8001
doyleco@ohsu.edu

Wayne Clark, MD
Principal Investigator
United States Pennsylvania Bryn Mawr 19010 Lankenau Institute for Medical Research
Joan Brown
610-649-1175
joanbrown140@aol.com

Gary H. Friday, MD
Principal Investigator
United States Pennsylvania Hershey 17033 Penn Stat-Hershey Medical Center (NINDS-CRC site)
Kimbra Hitz
717-531-4924
khitz@hmc.psu.edu

Raymond Reichwein, MD
Principal Investigator
United States Pennsylvania Philadelphia 19140 Temple University
Hannah Reimer
215-485-8183
paindromehannah@hotmail.com

Nina Gentile, MD
Principal Investigator
United States Pennsylvania Pittsburgh 15212 Allegheny Singer Research Institute
Melissa Tan
412-359-3748
mtian@wpahs.org

Ashis Tayal, MD
Principal Investigator
United States Tennessee Nashville 37212 Vanderbilt
Diane Brown
615-936-0062
diane.brown@vanderbilt.edu

Howard Kirschner, MD
Principal Investigator
United States Texas Dallas 75390-8897 University of Texas, Southwestern
J. Gregory Wright
214-648-0363
james.wright@utsouthwestern.edu

Mark Johnson, MD
Principal Investigator
United States Texas Houston 77030 Methodist Neurological Institute
Ken Ling, MD
832-576-7998
kenling@gmail.com

James Ling, MD
Principal Investigator
United States Utah Salt Lake City 84132 University of Utah
Janet Woodruff
801-581-2631
janet.woodruff@hsc.utah.edu

Elaine Skalabrin, MD
Principal Investigator
United States Vermont Burlington 05405 University of Vermont
Sharon Kenney
802-656-9094
sharon.kenney@med.uvm.edu

Mark Gorman, MD
Principal Investigator
United States Virginia Charlottesville 22908 University of Virginia
Colleen Harman, RN
434-924-9664
cph@virginia.edu

Nina Stolenski, MD
Principal Investigator
United States Virginia Norfolk 23507 Sentara Medical Group
Janet Rathbun
757-261-4986
jmrccrn@aol.com

Richard Zweifler, MD
Principal Investigator
United States Wisconsin Madison 53792 University of Wisconsin
Diane Dowd
608-287-2863
dmd@clinicaltrials.wisc.edu

Justin Sattin, MD
Principal Investigator
United States Wisconsin Milwaukee 53226-3596 Medical College of Wisconsin
Erin Brandenburg
414-805-8328
ebrand@mcw.edu

Michel T. Torbey, MD
Principal Investigator
Australia New South Wales Bedford Park 5042 Flinders Medical Centre
Sara Laubscher
61-7-8204-5781
sara.laubscher@health.sa.gov.au

David Schultz, MD
Principal Investigator
Australia New South Wales Camperstown 2050 Royal Prince Alfred
Irene Hegarty
61-2-9515-3251
irene.hegarty@sswahs.nsw.gov.au

Craig Anderson, MD
Principal Investigator
Australia New South Wales New Lambton Heights 2305 John Hunter Hospital (University of Newcastle)
Michelle Russell
61-2-4921-3481
michelle.russell@hnehealth.nse.gov.au

Mark Parsons, MD
Principal Investigator
Australia Victoria Box Hill 3128 Box Hill Hospital (Eastern Health)
Anne Buckland
61-3-9895-0302
anne.buckland@med.monash.edu.au

Christopher Bladin, MD
Principal Investigator
Australia Victoria Footscray 3011 Western Hospital (University of Melbourne)
Lyndy-ellen Paxcoe
61-3-8345-6766
lyndyellen@hotmail.com

Tissa Wijeratne, MD
Principal Investigator
Australia Victoria Heidelberg Heights 3801 Austin Health (National Stroke Research Institute)
Ros Melling
61-3-9496-2607
rmelling@nsri.org

Helen Dewey, MD
Principal Investigator
Australia Victoria Parkville 3050 Royal Melbourne Hospital
Melissa Ugalde
61-3-9342-7743
melissa.ugalde@mh.org.au

Stephen Davis, MD
Principal Investigator
Australia Western Australia Perth 6000 Royal Perth
Anne Claxton
61-8-9224-3461
anne.claxton@health.wa.gov.au

Graeme Hankey, MD
Principal Investigator
Canada Alberta Edmonton T6G2B7 University of Alberta
Frederika Herbert
780-407-3383
frederika.herbert@ualberta.ca

Ashfaq Shuaib, MD
Principal Investigator
Canada Alberta Lethbridge T1J0N9 Center for Neurologic Research
Carolyn Walker
403-329-4828
c-nr@shaw.ca

Toni Winder, MD
Principal Investigator
Canada British Columbia Victoria V8R4R2 Vancouver Island Health Research Centre
Leslie Atkins
250-370-8111 ext. 2840
leslie.atkins@viha.ca

Andrew Penn, MD
Principal Investigator
Canada Ontario London N6G2V2 Robarts Research Institute
Margot Giannetti
202-877-1071
margot.giannetti@medstar.net

Richard Chan, MD
Principal Investigator
Canada Ontario Ottawa k1Y 4E9 Ottawa Hospital-General Campus
Melodie Mortensen
613-798-5555 ext. 16217
mmortensen@ohri.ca

Makul Sharma, MD
Principal Investigator
Canada Ontario Thunder Bay P7B7C7 Intermountain Research Consultants
Sandra Stoger
807-684-6044
stogers@tbh.net

Saleem Malik, MD
Principal Investigator
Canada Ontario Toronto M5B1W8 St. Michael's Hospital
Pawel Kostyrko
416-864-5505
kostyrkop@smh.toronto.on.ca

Neville H. Bayer, MD
Principal Investigator
Canada Quebec Greenfield Park J4V 2H1 Hôpital Charles LeMoyne
Louise-Marie Beliveau
450-466-5000 ext. 2469
louise-marie.beliveau@rrsss16.gouv.qc.ca

Leo Berger, MD
Principal Investigator
Canada Quebec Montreal H3T1E2 McGill-Jewish General
Claudia Schanz
514-340-8222 ext. 2544
cschanz@neu.jgh.mcgill.ca

Jeffrey Minuk, MD
Principal Investigator
Canada Quebec Montreal H3G1A4 McGill-Montreal General
Anne Marie Fontaine
514-934-1934 ext. 44303
anne-marie.fontaine@muhc.mcgill.ca

Robert Cote, MD
Principal Investigator
Canada Quebec Quebec City G1J1Z4 Centre Hospitalier Affilie Universitaire de Quebec
Sophie Dube
418-649-5892
sophie.dube.cha@ssss.gouvqc.ca

Ariane Mackey, MD
Principal Investigator
Canada Montreal H2L4M1 CHUM-Centre de recherche, Hôpital Notre-Dame
Marlene Lapierre
514-890-8000 ext. 26242
marlene.lapierre.chum@ssss.gouvqc.ca

Andre Durocher, MD
Principal Investigator
Germany Altenburg 04600 Klinikum Altenburger Land
Anett Stoll
49-3447-521364
studienarzt-altenburg@web.de

Jorg Berrouschot, MD
Principal Investigator
Germany Bad Neustadt 97616 Neurologische Klinik
Hassan Soda
49-9771-9080
h.soda@neurologie-bad-neustadt.de

Bernd Griewing, MD
Principal Investigator
Germany Dresden 01307 University Hospital-Dresden
Immanuel Dzialowski, MD
49-351-15168
immanuel.dzialowski@uniklinikum-dresden.de

Ulf Becker, MD
Principal Investigator
Germany Duesseldorf 40225 University Duesseldorf/Heinrich-Heine University
Claudia Koering
49-211-81-19237
claudia.koering@uni-duesseldorf.de

Sebastian Jander
Principal Investigator
Germany Erlangen 91054 University of Erlangen
Anja Schmidt
49-9131-8534673
anja.schmidt@uk-erlangen.de

Hagen Huttner, MD
Principal Investigator
Germany Essen 45131 Alfried Krupp Hospital
Birgit Lyss
49-201-434-41418
birgit.lyss@krupp-krankenhaus.de

Peter Berlit, MD
Principal Investigator
Germany Frankfurt 60528 University Hospital Frankfurt
Isabel Dos Santos
49-69-6301-87745
isabel.dos.santos@uni-frankfurt.de

Tobias Neumann-Haefelin, MD
Principal Investigator
Germany Freiburg 79106 Freiburg University
Ulrike Bergmann
49-761-270-5193
ulrike.bergmann@uniklinik-freiburg.de

Andreas Hetzel, MD
Principal Investigator
Germany Griefswald 17475 Ernst-Moritz-Arndt-University Greifswald
Ellen Nieber
49-3834-86-6808
elnieber@uni-greifswald.de

Ulf Schminke, MD
Principal Investigator
Germany Halle 06120 Martin-Luther-Universitaet Halle-Wittenberg
Dana Richter
49-345-557-7033
dana.richter@medizin.uni-halle.de

Katja Wartenberg, MD
Principal Investigator
Germany Hamburg 20246 University Medical Center Hamburg-Eppendorf
Dagmar Otto
49-40-7410-59824
d.ott@uke.de

Michael Rosenkranz, MD
Principal Investigator
Germany Heidelberg 69120 University Heidelberg
Perdita Beck
49-6221-56-38121
perdita.beck@med.uni-heidelberg.de

Peter Ringleb, MD
Principal Investigator
Germany Jena 07747 Friedrich Schiller-University Jena
Claudia Herzau
49-364-19-323405
claudia.herzau@med.uni-jena.de

Otto Witte, MD
Principal Investigator
Germany Mainz 55131 University Hospital Mainz
Kristine Beutel
49-6131-17-2222
beutel@neurologie.klink.uni-mainz.de

Sven Klimpe, MD
Principal Investigator
Germany Muenster 48149 University Hospital Muenster
Dorothee Schulte to Buehne
49-251-83-49686
tobuehne@uni-muenster.de

Martin Ritter, MD
Principal Investigator
Germany Munich 81377 Klinikum der Universitat Muenchen
Angelika Doerr
49-89-7095-3672
angelika.doerr@uni-muenchen.de

Martin Dichgans, MD
Principal Investigator
Germany Ulm 89081 University of Ulm
Sabine Raubold
49-731-177-5721
sabine.raubold@uni-ulm.de

Roman Huber
Principal Investigator
Israel Beer Sheva POB151 Soroka Medical Center
Dafna Dalla-Torre
972-54-6368063
dafnad@bgu.ac.il

Itzhak Wirguin, MD
Principal Investigator
Israel Haifa 31096 Rambam Medical Center
Svetlana Mihlina
972-50-206-1771
s_mihlina@rambam.health.gov.il

David Yarnitsky, MD
Principal Investigator
Israel Haifa 31048 B'nai Zion Medical Center
Ludmila Milman
972-505-773475
Luda.milman@b-zion.org.il

Boaz Weller
Principal Investigator
Israel Haifa 31048 Bnai-Zion Medical Center
Ludmila Milman
972-505-773475
luda.milman@b-zion.org.il

Boaz Weller, MD
Principal Investigator
Israel Holon 58100 Wolfson Medical Center
Mary Israelson
972-3-5010524
maryisraelson@gmail.com

Yair Lampl, MD
Principal Investigator
Israel Petach Tikva 49372 Rabin Medical Center-Golda Campus
Nahum Roizin
972-3-9372261
nahumr@clalit.org.il

Jonathan Streifler, MD
Principal Investigator
Israel Ramat Gan 52621 Sheba Medical Center
Maya Toashi
972-3-5305744
Maya.toashi@sheba.health.gov.il

David Tanne, MD
Principal Investigator
Israel Tel Aviv 64239 Tel Aviv Medical Center
Orit Bar'am
972--3-6973414
oritb@tasmc.health.gov.il

Natan Bornstein, MD
Principal Investigator
Italy Laquila 67100 University of Laquila
Simona Sacco
39-0862-368533
simona.sacco@yahoo.com

Antonio Carolei, MD
Principal Investigator
Italy Milan 20132 University Vita Salute San Raffaele
Maria Sessa
39-02-2643-2990
sessa.maria@hsr.it

Giancarlo Comi
Principal Investigator
Italy Pavia 27100 IRCCS FONdazione Istituto Neurologico C. Mondino
Monica Gattinoni
39-038-2380252
monica.gattinoni@mondino.it

Giuseppe Miciieli, MD
Principal Investigator
Italy Perugia 06100 University of Perugia
Mauritzio Paciaroni
0755892875
mpaciaroni@hotmail.com

Valeria Caso, MD
Principal Investigator
Italy Roma 00189 University of Rome (S. Andrea Hospital)
Alessandra Spalloni
39-0633775774
alessandra.spalloni@gmail.com

Maurizia Rasura
Principal Investigator
Italy Rome 00168 Sacred Heart Catholic University
Vincenzo Di Lazzaro
39-0630-156321
vdilazzaro@rm.unicatt.it

VIncenzo Di Lazzaro, MD
Principal Investigator
Italy Rome 00161 University of Rome La Sapienza
Maria Teresa Di Mascio
39-0649979595
mariateresa.dimascio@yahoo.it

Danilo Toni, MD
Principal Investigator
Italy Vibo Valentia 89900 Jazzolino Hospital
Domenico Consoli
096-39-62312
neurologiavv@live.it

Domenico Consoli
Principal Investigator
Puerto Rico San Juan 00936 University of Puerto Rico
Pura Fuste
787-759-0306 ext. 228
pfuste@rcm.upr.edu

Fernando Santiago, MD
Principal Investigator
United Kingdom Dorset Bournemouth BH7 7DW Royal Bournemouth
Anna Orpen
44-1202-704504
anna.orpen@rbch.nhs.uk

Damian Jenkinson, MD
Principal Investigator
United Kingdom Kent Margate CT9 4AN Queen Elizabeth The Queen Mother Hospital
Sally Jones
44-1843-225544 ext. 63031
sally.jones@ekht.nhs.uk

George Thomas, MD
Principal Investigator
United Kingdom Lancashire Blackpool FY3 8NR Blackpool Victoria Hospital
Hannah Goddard
44-1253-303729
hannah.goddard@bfwhospitals.nhs.uk

James McIlmoyle, MD
Principal Investigator
United Kingdom Northumberland Ashington NE63 9JJ Wansbeck General Hospital
Catherine Ashbrook-Raby
44-1670-529442
catherine.ashbrook-raby@nhct.nhs.uk

Christopher Price, MD
Principal Investigator
United Kingdom Scotland Glasgow G4 0SF Glasgow Royal Infirmary
Ruth Graham
44-141-232-0970
ruth.graham@ggc.scot.nhs.uk

Peter Langhorne, MD
Principal Investigator
United Kingdom Scotland Glasgow G51 4TF Southern General Hospital
Angela Welch
44-141-201-2836
angelawelch@nhs.net

Keith Muir
Principal Investigator
United Kingdom Scotland Glasgow G21 3UT Stobhill Hospital
Ruth Graham
44-141-201-3012
ruth.graham@ggc.scot.nhs.uk

Christine McAlpine, MD
Principal Investigator
United Kingdom Tyne and Wear Gateshead NE9 6SX Queen Elizabeth Hospital Gateshead
Eleanor Morrell
44-191-445-2843
ellie.morrell@ghnt.nhs.uk

David Barer, MD
Principal Investigator
United Kingdom Aberdeen AB25 2ZN Aberdeen Royal Infirmary
Anu Joyson
44-1224-559503
ajoyson@nhs.net

Mary Macleod
Principal Investigator
United Kingdom Airdrie ML6 7UN Monklands Hospital
Derek Esson
44-1236-712484
derek.esson@lanarkshire.scot.nhs.uk

J. Mark Barber
Principal Investigator
United Kingdom Ashford TN24 OLZ William Harvey Hospital
Linda Cowie
44-1233-616214
linda.cowie@ekht.nhs.uk

David Hargroves, MD
Principal Investigator
United Kingdom Bath BA1 3NG Royal United Hospital
Denise Button
44-1225-824120
denise.button@ruh-bath.swest.nhs.uk

Louise Shaw, MB
Principal Investigator
United Kingdom Cambridge CB2 2QQ Addenbrookes Foundation NHS Trust (Cambridge)
Julie White
44-1223-256752
juliewhite@addenbrookes.nhs.uk

Eoin O'Brien, MD
Principal Investigator
United Kingdom Cheshire CH2 IUL Countess of Chester Foundation Trust
Christine Kelly
44-1244-365894
christine.kelly@coch.nhs.uk

Kausik Chatterjee, MD
Principal Investigator
United Kingdom Dewsbury WF13 4HS Dewsbury District Hospital
Ann Needle
44-7966-447-403
ann.needle@nhs.net

Prabal Datta, MD
Principal Investigator
United Kingdom Essex SS0 0RY Southend University Hospital
Christopher Khuoge
44-1702-435555 ext. 8301
christopher.khuoge@southend.nhs.uk

Paul Guyler, MD
Principal Investigator
United Kingdom Exeter EX2 5DW Devon PCT
Nicola Wedge
44-1392-406-434
nicola.wedge@rdeft@nhs.uk

William Strain, MD
Principal Investigator
United Kingdom Exeter EX2 5DW Royal Devon and Exeter
Nicola Wedge
44-1392-406434
nicola.wedge@rdeft.nhs.uk

William Strain, MD
Principal Investigator
United Kingdom Guildford GU2 7XX Royal Surrey County Hospital
Caroline Lawlor
44-07890-034950
c.lawlor@nhs.net

Kath Pasco, MD
Principal Investigator
United Kingdom Halifax HX3 0PW Calderdale Royal Hospital
Christopher Button
44-1422-224526
christopher.button@cht.nhs.uk

Irfan Shakir, MD
Principal Investigator
United Kingdom Liverpool L7 8XP The Royal Liverpool and Broadgreen University Hospitals
Glyn Fletcher
44-151-706-3105
glyn.fletcher@ribuht.nhs.uk

Aravindakshan Manoj, MD
Principal Investigator
United Kingdom Liverpool L9 7AL University Hospital Aintree
Helen Martin
44-151-529-3839
helen.martin@aintree.nhs.uk

Ramash Durairaj, MD
Principal Investigator
United Kingdom London SE5 9RS Kings College London
Enock Khoromana
44-203-299-7770
enock.khoromana@nhs.net

Lalit Kalra, MD
Principal Investigator
United Kingdom London SW17 ORE Saint Georges University of London
Joanna O'Reilly
44-20-8725-3260
joreilly@sgul.ac.uk

Hugh Markus
Principal Investigator
United Kingdom Luton LU4 0DZ Luton and Dubstable Hospital
Frances Justin
44-1582-498218
frances.justin@ldh.nhs.uk

Lakshmanan Sekaran, MD
Principal Investigator
United Kingdom Middlesbrough TS4 3BW James Cook University Hospital
Kim Mitchelson
44-1642-854700
kim.mitchelson@nhs.net

David Lance Broughton, MD
Principal Investigator
United Kingdom Newcastle upon Tyne NE1 4LP Newcastle upon Tyne
John Davis
44-191-2821688
john.davis@nuth.nhs.uk

Anand Dixit, MD
Principal Investigator
United Kingdom Torquay TQ2 7AA Torbay Hospital (South Devon Healthcare NHS Foundation Trust)
Caroline Hilaire
44-1803-656615
caroline.hilaire@nhs.net

Debs Kelly, MD
Principal Investigator
United Kingdom Tyne and Wear NE29 2NH North Tyneside General Hospital
Judith Murdy
44-191-2934126
judithmurdy@nhs.net

Helen Rodgers, MD
Principal Investigator

Contact

Walter N. Kernan, M.D.
203-764-7000

NCT ID: NCT00091949

Date Last Changed: August 3, 2011

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