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Meningitis Clinical Trials

A listing of Meningitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (27) clinical trials

Evaluating Raised Intracranial Pressure Using MR Elastography

The goal of this study is to evaluate the brain elasticity in patients with idiopathic intracranial hypertension (IIH) and other forms of raised intracranial pressure, such as obstructive hydrocephalus. Investigators will evaluate for a correlation between brain stiffness and opening pressure on lumbar puncture. Investigators will also evaluate for changes ...

Phase N/A

Treatment With Tamoxifen in Cryptococcal Meningitis

A randomized, open-label trial with 2 parallel arms: standard antifungal therapy versus tamoxifen augmented antifungal therapy during the first 2 weeks (induction phase) of treatment. The study will recruit in two sites in Ho Chi Minh City: the Hospital for Tropical Diseases (HTD), and Cho Ray Hospital (CRH). 25 patients ...


Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis

There is a longstanding hypothesis that death from TBM results from an excessive intracerebral inflammatory response. The corollary of this hypothesis has been that adjunctive anti-inflammatory treatment with corticosteroids (e.g. dexamethasone) improves survival, which has been demonstrated in predominantly HIV-uninfected individuals in a small number of trials. Yet how corticosteroids ...


Safety Study of Meningococcal ACYW135 Polysaccharide Conjugate Vaccine in Healthy Volunteers Aged Above 3 Months

The purpose of this study is to evaluate safety of meningococcal ACYW135 polysaccharide conjugate vaccine in healthy volunteers aged above 3 Months


Venous Sinus Stenting for Idiopathic Intracranial Hypertension Refractory to Medical Therapy

Idiopathic Intracranial Hypertension (IIH) is a disease that affects mainly young people, and is associated with headache and loss of vision. The medical and surgical management of IIH is problematic and many patients are not treated effectively. Some cases of IIH are associated with severe stenosis of the large veins ...


Improving the Diagnosis of Meningitis in Emergency Rooms

A point-of-care laboratory (POC) was set at North Hospital, Marseille, France for the diagnosis in less than two hours of meningitis caused by known pathogens, close to the reception of Emergency service. In this instance 30% of patients have no etiological diagnosis after the POC diarrhoea tests . This lab ...

Phase N/A

Blood-brain Barrier Permeability Study in Adults With Meningitis

Clinical trials in healthy volunteers and in patients with diagnosed blood-brain barrier disruption Performing a lumbar puncture as a routine diagnostic procedure in a patient with suspected neuroinfection. Biochemical assessment of the degree of the blood-brain barrier disruption based on the albumin ratio. Enrollment of patients diagnosed with neuroinfection to ...

Phase N/A

Penetration of Ceftaroline Into Cerebrospinal Fluid(CSF)

Ceftaroline is a piece of new cephalosporin very active on resistant staphylococci in methicillin (SEMR: Staphylococcus Epidermidis Resistant in Methicillin, SMAR: Staphylococcus Aureus Resistant in Methicillin)and/or in vancomycin ; Ceftaroline is also very active on pneumococci resistant in penicillin and/or 3rd generation of cephalosporins. Ceftaroline was approved by the European ...


Etiology of Orphan Community-based Meningitis and Meningo-encephalitis.

Community-based meningitis and meningo-encephalitis are defined by the presence of more than 10 leukocytes per mL of cerebrospinal fluid (CSF), eventually reported to the number of red blood cells. They can be associated with encephalitis, defined by cerebral or cerebellar dysfunction in the case of the transmission. The evolution includes ...

Phase N/A

A Surveillance Study of Diseases Specified as Adverse Events of Special Interest of Other Adverse Events Leading to Hospitalisation or Death and of Meningitis in Children in Africa Prior to Implementation of the RTS S/AS01E Candidate

The outcomes of interest (AESI, other AE leading to hospitalization or death, and meningitis) as well as data on malaria morbidity and mortality will be captured through active and enhanced hospitalization surveillance in children < 5 years of age. Children enrolled in active surveillance will be visited at their home ...

Phase N/A