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Manic Disorders Clinical Trials

A listing of Manic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (8) clinical trials

Evaluation of the Genetics of Bipolar Disorder

Bipolar affective disorder is a severe, heritable condition affecting about one percent of the population. The mode of inheritance is poorly understood and probably involves multiple loci of small to moderate effect. In this project, we use genetic mapping and sequencing methods to identify genetic markers and variations that contribute ...

Phase N/A

A clinical trial to evaluate treatments using Placebo Oral Tablet, N-Acetylcysteine, Gabapentin for patients

Bipolar disorder (BD) is the Axis I psychiatric condition most strongly associated with substance use disorder (SUD); diagnostic co-occurrence is particularly high between BD and alcohol use disorder (AUD). Individuals with co-occurring SUD and BD (SUD+BD) have substantially worse clinical outcomes than those with either BD or SUD alone. Nonetheless, ...


A clinical trial sponsored by Janssen Research & Development, LLC for a research study for the treatment of Bipolar Disorder

The primary purpose of this study is to compare, over 24 months, the time spent with clinically significant mood symptoms (ie, mania, depression), as measured by the Longitudinal Interval Follow-Up Evaluation (LIFE) and the Psychiatric Status Rating Scale (PSR), in offspring of bipolar parents with and without at least mild ...

Phase N/A

A clinical trial seeking patients for a research study of Minocycline

The investigators are doing this research study to find out if minocycline alone, N-acetyl cysteine (NAC) alone, or the combination of minocycline and NAC can help people with bipolar depression when added to lithium. The investigators also want to find out if minocycline, NAC, and the combination of minocycline and ...


A clinical trial seeking patients for a research study for the treatment of Endogenous depression, Bipolar Disorder, Depression

This trial will compare the trajectories of improvement for three different patterns of twice-daily rTMS in major depression: two daily sessions of dorsomedial prefrontal rTMS delivered at 0 min vs. 30 min vs. 60 min intervals.

Phase N/A

A clinical trial sponsored by National Institute of Mental Health (NIMH) for a research study for the treatment of Endogenous depression, Post-Traumatic Stress Disorder, Schizophrenia, Bipolar Disorder, Major depression

Objective: The mission of Human Brain Collection Core (HBCC) is to gain insight into the causes and mechanisms of mental disorders. Study Population: To be able to conduct this research, we obtain brain and other tissues from deceased individuals with and without psychiatric disorders. Study Design: This protocol provides the ...

Phase N/A

A clinical trial to evaluate treatments using Placebo of Abilify 2, 5, 10, 15mg (Tablet), Abilify 2, 5, 10, 15mg (Tablet) for patients with Bipolar Disorder

This is an 8-week, multicenter, randomized, double blind, placebo controlled study to evaluate the efficacy and safety of aripiprazole as an adjunctive treatment with mood stabilizer for the treatment of patients (outpatients or inpatients) with type I or II bipolar disorder accompanied by major depressive episode, without any psychotropic features. ...


A Phase 2 clinical study for patients with Suicide attempt, Suicidal Ideation, Bipolar Disorder, Suicidal Ideas

NeuroRx is developing NRX-101, a fixed-dose combination oral capsule composed of d-cycloserine (DCS) and lurasidone for the maintenance of remission from Acute Suicidal Ideation and Behavior (ASIB) in adults with Bipolar Depression following initial stabilization. The proposed oral combination product is intended to be administered as part of a sequential ...