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Liver Disease Clinical Trials

A listing of Liver Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (180) clinical trials

This study is being conducted to evaluate the efficacy, safety and tolerability of GSK2330672 administration for the treatment of pruritus (itch) in participants with primary biliary cholangitis (PBC). Participants will be treated with either placebo or one of the 4 dose regimens of GSK2330672 (20 milligram [mg], 90 mg or ...

Phase

Clinical Trials of Texas, Inc. is conducting a research study of an investigational medication for patients with non-alcoholic fatty liver disease accompanied by high cholesterol. Qualified participants receive study-related medical care from a board-certified physician, study medications, exams and evaluations.

Phase

Concerned about high blood cholesterol and fatty liver disease? Wake Research Associates is enrolling volunteers in a study of the safety and effectiveness of an investigational drug for hypercholesterolemia and non-alcoholic fatty liver disease (NAFLD).

Phase

Seladelpar (MBX-8025) in Subjects With Primary Biliary Cholangitis (PBC)

Primary To evaluate the safety and efficacy of MBX-8025 2 mg, 5 mg, and 10 mg over 8 weeks of treatment Secondary To evaluate the safety and efficacy of MBX-8025 2 mg, 5 mg, and 10 mg over 12 and 26 weeks of treatment To evaluate the safety and efficacy ...

Phase

Saroglitazar Magnesium in Patients With Nonalcoholic Fatty Liver Disease and/or Nonalcoholic Steatohepatitis

This is a randomized, double-blind, placebo-controlled study in up to 104 patients with a diagnosis of NAFLD and/or NASH. The study will be conducted over a period of up to 22 weeks and will include an optional Prescreening, Screening (Days -35 to -7) Phase, a 16-week Treatment Phase following randomization ...

Phase

A Phase 2 Study of Brivanib in Chinese Patients With Previously Treated Advanced HCC

This is a Phase 2, Open-label, Randomized, Multicenter Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Brivanib in Patients with Previously Treated Advanced Hepatocellular Carcinoma.

Phase

TATE Versus TACE in Intermediate Stage HCC

Trans-arterial chemoembolization (TACE) is a standard care of intermediate stage Hepatocellular carcinoma (HCC) for 40 years without much improvement in efficacy. The key reason for lack of progress is that chemotherapy agents are not effective in hypoxia and cancer stem cells are induced under hypoxia. Tirapazamine, a hypoxia activated agent, ...

Phase

Combination of TATE and PD-1 Inhibitor in Liver Cancer

The goal of the study is to investigate whether tumor necrosis induced by TATE treatment can boost anti-tumor immunity and enhance the therapeutic efficacy of immune checkpoint inhibitor. Patients with advanced HCC or metastatic CRC with liver lesions will be enrolled in the study. Liver lesions will be treated with ...

Phase

A Study of Epacadostat an IDO1 Inhibitor in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

The purpose of this study is to test any good and bad effects of the combination therapy of epacadostat and pembrolizumab and to determine how well the combination therapy works in the treatment of patients with sarcoma.

Phase