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Bladder Carcinoma Clinical Trials

A listing of Bladder Carcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (108) clinical trials

Quality of Life in Patients With Bladder Cancer

OBJECTIVES: - To study the effects of recurrence and progression on health-related quality of life (HRQL). - To study the effects of repeat cystoscopy on HRQL. - To study the patients' assessments of a hypothetical prognostic model and how this affects their preference for the mode of surveillance. OUTLINE: This ...

Phase

Selenium and Vitamin E in Preventing Cancer Progression and Recurrence in Patients With Early-Stage Bladder Cancer

OBJECTIVES: - To investigate whether selenium and/or vitamin E (α-tocopherol) supplementation reduces the risk of recurrence and progression. OUTLINE: This is a multicenter study. Patients are stratified by recurrence risk group (high vs intermediate) and treatment center and randomized to 1 of 4 treatment arms. - Arm I: Patients receive ...

Phase

Effect of Dietary Lifestyle and Environmental Factors on Patients With Early-Stage Bladder Cancer

OBJECTIVES: - To examine if common and potentially modifiable dietary, lifestyle, and environmental exposures affect the risk of recurrence and progression in bladder cancer. OUTLINE: This is a multicenter study. Detailed information will be collected about the patients' lifestyle and their exposure to risk factors associated with bladder cancer using ...

Phase

Study of Genes and Environment in Patients With Cancer in East Anglia Trent or West Midlands Regions of the United Kingdom

OBJECTIVES: - To obtain epidemiological information and biological material on a population-based series of cancer cases, including malignant melanoma, lymphoma, bladder, kidney, esophageal, and pancreatic cancer, and brain tumors. - Identify novel cancer susceptibility genes, by comparison of genotype frequencies in cases with the corresponding frequencies in large control series. ...

Phase N/A

Phase I & II Trial of Intravesicular Abraxane for Treatment-refractory Bladder Cancer

The intravesical treatment of bladder cancer with Abraxane is more desirable than other taxanes due to its ability to be diluted in water and not lipid-based solutions allowing it greater access to sites in the bladder. Thus, we are interested in investigating Abraxane's safety, toxicity, and efficacy profile for the ...

Phase

Biomarkers and Radiation Side Effects in Patients Undergoing Radiation Therapy for Gastrointestinal Cancer

OBJECTIVES: Primary - Determine if tumor-specific DNA mutations and aberrant DNA methylation can be detected in the serum, urine, or stool at the time of diagnosis in patients undergoing radiotherapy for gastrointestinal malignancies. - Determine if changes in mutational status at follow up are associated with disease persistence, recurrence, or ...

Phase N/A

Single Agent Abraxane as Second Line Therapy in Bladder Cancer

For those patients with advanced bladder cancer who have progressed on a platinum based regimen, no widely accepted standard second line therapy currently exists. Taxanes including paclitaxel have exhibited clinical activity in this disease and are sometimes given off study. However, toxicities including neurotoxicity and hypersensitivity reactions often limit the ...

Phase

Study of Individuals and Families at High Risk for Cancer

OBJECTIVES: - Identify individuals at high risk of cancer, especially due to personal or family medical history. - Evaluate and define clinical spectrum of disease in syndromes predisposing to cancer. - Quantify risks of tumors in family members. - Map, clone, and determine function of tumor susceptibility genes. - Identify ...

Phase N/A

Screening for Bladder Cancer

Reduction of cancer mortality is a stated goal of the National Cancer Institute. Cancer of the bladder is the 4th most commonly diagnosed cancer and 7th leading cause of cancer death in the American men, and represents an important target for mortality-reducing efforts. Furthermore, these tumors, even in early (i.e. ...

Phase N/A

Tamoxifen in Treating Patients With Metastatic Bladder Cancer That Did Not Respond to Previous Chemotherapy

OBJECTIVES: Primary - To assess the 4-month freedom from progression in patients with progressive metastatic transitional cell carcinoma of the bladder treated with tamoxifen citrate. Secondary - To determine the objective response rate. - To correlate response with estrogen-receptor status of the metastatic tumor. - To collect data on the ...

Phase