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Eye Disease Clinical Trials

A listing of Eye Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (393) clinical trials

Treatment of Graves Ophthalmopathy With Diclofenac or Simvastatin (GO-DS)

Progression of GO from mild-moderate to severe disease: Criteria for start of treatment with corticosteroids, retrobulbar irradiation, or orbital decompression are severe soft tissue swelling (NO SPECS class 2c), risk of corneal ulcers with or without exophthalmos, double vision within 30 degrees, and optic nerve dysfunction. Patients who progress will ...


Femtosecond Laser-assisted Corneal Debridement for Herpes Simplex Keratitis

The purpose of the study is to learn if adding femtosecond laser-assisted corneal debridement to a standard therapy of oral ganciclovir can help shorten the healing time of herpes simplex epithelial keratitis (HSK).

Phase N/A

Corneal Epithelial Autograft for Pterygium

The purpose of the study is to explore whether femtosecond laser-assisted cornea epithelial autograft is more effective than limbal conjunctival autograft for ocular surface reconstruction after excision of pterygium.

Phase N/A

Visual Performance Intraocular Lens (IOL) MicroPure 1.2.3.

The examinations consist of visual acuity data, contrast sensitivity exams, slitlamp examinations and posterior capsule opacification (PCO) grading. Follow up will be up to 24 months postoperative.

Phase N/A

AcrySof Toric IQ Post-Market Clinical Study

Patients will be examined pre-operatively to up to 3 years post-operatively. One eligible eye will be selected as a target eye for efficacy analysis. If both eyes are eligible, the eye in which the IOL is implanted first will be selected as the target eye.

Phase N/A

A Nutritarian Study to Evaluate the Effectiveness of Lifestyle Changes in Chronic Disease Prevention Especially Cancer

The Nutritional Research Foundation, in conjunction with Northern Arizona University, is conducting a long-term health study for women ages 18 and older. This study will address the effects of a nutrient dense, plant-rich diet on the long-term risks of cancer and other chronic diseases. Participants enroll in a 30-day training ...

Phase N/A

Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy

Patients will be recruited from multiple community and hospital-based practices that care for pregnant women. Subjects will have: measurements of body composition anthropometric measures sleep and mood questionnaires Home sleep studies blood testing for biological markers salivary testing for hormonal markers pulmonary function tests and upper airway patency measurements Women ...

Phase N/A

Natural History Study of Synucleinopathies

-synuclein is a small protein of 140 amino acids that is highly expressed in the brain. It's function remains poorly understood.10 Synucleinopathies are a group of neurodegenerative diseases associated with the abnormal accumulation of -synuclein within cytoplasmic inclusions in neurons or oligodendroglia. These -synuclein containing cytoplasmic aggregates occur throughout the ...

Phase N/A

Effectiveness of Intense Pulsed Light for Improving Dry Eye Syndrome

Outcome measures (tear break-up time,meibography, self-assessed symptoms and close up photos of the lid margins) will be measured at baseline. All subjects will receive 4 treatments at 2 weeks intervals. In each treatment session, a subject allocated to the study group will be treated with intense pulsed light (IPL) administered ...

Phase N/A

Impact of Sleep Restriction on Performance in Adults

Chronic Sleep Restriction (SR) is highly prevalent in today's modern society. Artificial light, portable electronic devices, and 24-h services have allowed individuals to remain active throughout the night, leading to reductions in sleep duration. SSD has been linked to obesity and our laboratory has been interested in establishing whether sleep ...

Phase N/A