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Vision Loss Clinical Trials

A listing of Vision Loss medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (28) clinical trials

Do you or your child have cataracts in both eyes? If so, you might be interested in a voluntary observational research study for people who were diagnosed with cataracts in both eyes at a young age. This study involves no medication. Who can participate? You or your child may be ...

Phase N/A

Neuromyelitis Optica (NMO) or NMO Spectrum Disorders (NMOSD), also known as Devic’s Disease, is a rare, severe disabling autoimmune inflammatory disorder of the central nervous system (CNS) that predominately affects the optic nerves and spinal cord, and is often characterized by a relapsing course. Throughout this protocol the term NMO ...

Phase N/A

Efficacy and Safety Study of Bilateral Intravitreal Injection of GS010 for the Treatment of Vision Loss up to 1 Year From Onset in LHON Due to the ND4 Mutation

The goal of this clinical trial is to assess the safety and efficacy of GS010, a gene therapy, in improving the retina functional & structural outcomes in subjects with LHON due to the G11778A ND4 mitochondrial mutation when vision loss duration is present up to one year.


Spatial Cognitive Training

The investigators will recruit 40 blind participants, randomized by the investigators' CVNR statistician into two groups. One group will undergo the experimental intervention (spatial cognitive training) and the other will undergo a control intervention involving letter-number matching. The participants will include women and minorities in proportion to the demographics of ...

Phase N/A

Collision Warning Device for Blind and Visually Impaired

Participants with blindness or severe visual field loss (hemianopia or tunnel vision) will be trained to use a collision warning device that alerts them to impending collisions. Participants will use the device at home during everyday mobility for 2 months. The device is designed to supplement existing mobility devices, such ...

Phase N/A

Head Mounted Eye Tracking Aide for Loss of Central Vision (HETALCEV)

Participants with bilateral central scotomas will be selected for this study during their routine clinical visits at the University of Minnesota Eye Clinic. Written consent will be obtained from all participants. Each participant will have their scotomas mapped using a Nidek MP-1 microperimeter housed in the psychology department to give ...

Phase N/A

Spectacles for Patients With Down Syndrome

Individuals with Down syndrome suffer from significant ocular complications including high levels of lower-order refractive error (sphere and cylinder) and elevated levels of higher-order aberrations. These optical factors likely contribute to the poor acuity observed in this population. Current clinical prescribing practices may under-serve this community, as the cognitive demands ...

Phase N/A

Providing Access to the Visual Environment

Subjects are enrolled each school year based on referrals from school systems in Tennessee, ophthalmologists, and optometrists. A total of 90 new students are enrolled each year. Students are provided a comprehensive low vision rehabilitation evaluation by a low vision optometrist and prescribed optical devices to improve distance appreciation, near ...

Phase N/A

Multisensory Body and Space Representations (BASES-EXTINCTION)

To accurately control body movements to interact with objects, our brain needs representations of the body and the nearby space. The broader aim of this research project is to study the behavioural and physiological mechanisms involved in the constitution of these representations, to identify their neural bases, in order to ...

Phase N/A

Visual Information Restoration and Rehabilitation Via Sensory Substitution Technology in Children

Objective Our objective is to determine if the functional improvements seen in blind subjects using the BrainPort can be realized in a pediatric cohort. Specific Aims: The aim of this proposal is to evaluate a non-surgical visual prosthetic (BrainPort vision device) that enables the blind to appreciate their immediate surroundings ...

Phase N/A