Home » Clinical Trials »  Search Clinical Trials

Therapeutic Areas:  |  Gastroenterology

Search Medical Condition
Please enter condition
Please choose location

Hernia Clinical Trials

A listing of Hernia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (152) clinical trials

Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen

This is a double-blind randomized trial of intravaginal estrogen (conjugated estrogens, 0.625mg/1g cream) vs. placebo in postmenopausal women (n=222 total) with symptomatic prolapse beyond the hymen planning transvaginal native tissue repairs. Medication will be started 6-8 weeks before surgery and continued for 1 year postoperatively, i.e. until scar remodeling is ...

Phase

A Comparison of Fortiva and Strattice Tissue Matrices in Complex Ventral Hernia Repair

This is a randomized, prospective, double-blinded study evaluating the efficacy of Fortiva Porcine Dermis versus Strattice Reconstructive Tissue Matrix in 120 patients with large complex abdominal wall ventral hernias undergoing single stage repair. The patient will be blinded to treatment as well as an independent qualified evaluator to confirm evidence ...

Phase N/A

The neoClose Abdominal Closure vs Carter-Thomason Trial

Both the neoClose abdominal closure to the standard Carter-Thomason closurewill be used to close 12 mm camera and stapler port sites upon completion of a robotic assisted laparoscopic gastric bypass. The procedure requires a 12 mm port be placed in the midline approximately 3 cm cephalad to the umbilicus and ...

Phase N/A

XenMatrix AB Surgical Graft in Ventral or Incisional Midline Hernias

This is a post-market, on-label study to understand the performance of the graft in the US.

Phase N/A

A Prospective Trial of a Bio-absorbable Mesh in Challenging Laparoscopic Ventral or Incisional Hernia Repair

Subjects at high risk are defined as having 1 or more of the following co-morbid conditions: body mass index (BMI) between 30-40 kg/m2, inclusive, active smokers, chronic obstructive pulmonary disease (COPD), diabetes, immunosuppression, coronary artery disease, chronic corticosteroid use, low pre-operative serum albumin, advanced age, or renal insufficiency.

Phase N/A

A Prospective Study to Compare the Clinical Outcomes Pain and Patient Quality of Life for Hernia Patients

The objective of this prospective, multi-center post-market study is to prospectively collect uniform, evidence based outcomes for patients undergoing open, laparoscopic or robotic assisted hernia repair. The outcomes that will be collected include various routine clinical parameters, short term patient reported outcomes (quality of life, pain scores) and long term ...

Phase N/A

Effectiveness and Safety of Gordian Surgical's TroClose1200

Subjects that sign the Informed Consent Form will be evaluated for eligible for the study per eligibility criteria. Subject medical background and underlying disease requiring intervention will be taken at screening. Procedure will be scheduled. Subjects that will eventually, for any reason, will not be operated with the TroClose1200, will ...

Phase N/A

Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery

Neuromuscular blockade (NMB) is frequently utilized in laparoscopic procedures to improve surgical conditions by relaxing the abdominal muscles and thus facilitating insufflation with carbon dioxide to optimize surgical view. Increased airway pressures can lead to an increase in alveolar and perivascular edema, a decline in dynamic lung compliance and hypoxemia. ...

Phase

Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia

Study Summary All patients will complete a standard prenatal evaluation at the Center for Fetal Diagnosis and Treatment (CFDT) to find out if they are candidates. The standard clinical assessments include: Medical history and Physical exam, Level II ultrasound, Fetal echocardiogram, Fetal magnetic resonance imaging (MRI), and a Psychosocial assessment. ...

Phase N/A

The Use of Biologic Mesh vs Bioabsorbable Mesh During Ventral Hernia Repair in At-risk Patients

The goal of the proposed study is to evaluate the outcomes of patients implanted with Strattice (LifeCell Corporation, Branchburg, NJ, USA) and Gore Bio-A (W. L. Gore & Associates, Inc., Newark, DE, USA) for the repair of abdominal wall defects in at-risk patients. Primary endpoints of the study will include ...

Phase N/A