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Hernia Clinical Trials

A listing of Hernia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (48) clinical trials

Should Prosthetic Repair of Incisional Abdominal Hernias be Drain or Not?

Between 3 to 20% of patients who received a midline laparotomy will develop an incisional hernia. Primary suture of the defect is associated with a recurrence rate between 25 and 50%.Mesh repair is superior with regard to the recurrence (12-20%), but early postoperative complications include infections, hematomas and seromas. Some ...

Phase N/A

Effect of Intraoperative Infiltration With Bupivacain on the Development of Chronic Pain After Inguinal Hernia Repair

264 patients scheduled for an inguinal hernia repair using one of three procedures (Lichtenstein, Barwell and TEP = total extraperitoneal hernioplasty) are being randomly allocated intra-operatively into two groups. Group I patients receive a local injection of 20ml Carbostesin® 0.25% at the end of the operation according to a standardised ...

Phase

Characterization of Explanted Hernia Meshes From Human Subjects: A Multi-Center Prospective Study

This study will collect a large amount of hernia mesh explants and study the changes that occur in the materials in vivo to use the information to help design new mesh made from novel materials. We will have evidence that our current options are not only inadequate but can lead ...

Phase N/A

Continuous Versus Interrupted Abdominal Wall Closure After Emergency Midline Laparotomy

More than 700.000 open abdominal surgeries (laparotomies) are performed each year in Germany (2). A major surgical complication after laparotomy is abdominal fascia dehiscence which might appear either as early (burst abdomen with evisceration) or as late complication (incisional hernia). These patients usually undergo surgery for secondary fascial closure associated ...

Phase

International Hernia Mesh Registry

To help identify best practices leading to lower recurrence rates and decreases in chronic pain associated with the hernia repair procedure.

Phase N/A

Functional Outcome After Incisional Hernia Repair: Open Versus Laparoscopic Repair

Midline incisional hernia is reported from 0,5 to 11% after abdominal operations. Discomfort, pain, body image alteration and diminished quality of life influences functional well being. Alteration in pulmonary function, risk of visceral incarceration or cutaneous complications are potential medical complications. Primary repair without mesh reinforcement is almost abandoned because ...

Phase

Functional Outcome After Groin Hernia Mesh Repair: Open Versus Laparoscopy

Hernia repair is the most frequent elective operation performed in general surgery. Chronic pain or persistent neuralgia has been recognized as a complication after inguinal hernia repair but was reported in the 1980s as a rare and infrequent condition. Studies from the mid 1990s have reported a higher frequency, with ...

Phase

Laparoscopic Inguinal Hernia Repair- Transabdominal Preperitoneal (TAPP) Versus Totally Extra Peritoneal (TEP)

The following information from the literature was obtained by searching through the MEDLAR and PUBMED using the key words 'TAPP', 'TEP', 'Laparoscopy' and 'Inguinal hernia'. Application of laparoscopic techniques has revolutionized the field of surgery. General surgeons have accepted laparoscopic surgery unequivocally. Few would dispute the tremendous success and the ...

Phase N/A

Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years

Laparoscopic techniques have been applied widely to the management of various common pediatric surgical diseases. Current evidence lacks sufficient quality to justify the widespread adoption of the laparoscopic approach to the repair of inguinal hernias within children. It is important to critically evaluate the efficiency and the potential risks of ...

Phase N/A

Randomized Controlled Trial of Fetoscopic Endoluminal Tracheal Occlusion With a Balloon Versus Expectant Management During Pregnancy in Fetuses With Left Sided Congenital Diaphragmatic Hernia and Moderate Pulmonary Hypoplasia.

Isolated Congenital Diaphragmatic Hernia (CDH) can be diagnosed in the prenatal period, and remains associated with an 30 % chance of perinatal death and morbidity mainly because of pulmonary hypoplasia and pulmonary hypertension. In addition, in the survivors there is a high rate of morbidity with evidence of bronchopulmonary dysplasia ...

Phase N/A