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Familial Chylomicronemia Syndrome Clinical Trials

A listing of Familial Chylomicronemia Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (4) clinical trials

The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronemia Syndrome

This is a multi-center, open-label study for Group 1: ISIS 304801-CS6 (index study) roll-over FCS patients, Group 2: ISIS 304801-CS16 (index study) roll-over FCS patients, and Group 3: FCS patients who did not participate in the ISIS 304801-CS6 or ISIS 304801-CS16 index studies. All patients will receive volanesorsen 300 mg ...

Phase

Alipogene Tiparvovec for the Treatment of LPLD Patients

This is a prospective, interventional, randomised, open-label, parallel group study evaluating the clinical response as well as the dynamics of postprandial chylomicron metabolism in patients treated with alipogene tiparvovec with and without immunosuppressants. The study will be conducted in 12 LPLD patients who will be randomised into the Immuno+ (cyclosporin ...

Phase

Biomarker for Homozygous Familial Hypercholesterolemia

Homozygous familial hypercholesterolemia (HoFH) is a rare hereditary disorder of lipoprotein metabolism characterized by exceptionally high levels of low-density lipoprotein cholesterol (LDL-C). Clinical manifestations may vary but often include markedly premature coronary artery disease, supravalvular aortic stenosis due to aortic root atheroma, and cutaneous manifestations such as tendon xanthomata. Although ...

Phase N/A

GENIALL Lipoprotein Lipase Deficiency (LPLD) Disease Registry

The LPLD Registry is an observational, longitudinal, pharmaco-epidemiologic study in lipoprotein lipase deficient (LPLD) patients, either treated or not treated with Glybera to assess the long-term safety and efficacy of the drug, as well as the epidemiology of the disease. Data from a dietary questionnaire to be completed over a ...

Phase N/A