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Acute Myeloid Leukemia Clinical Trials

A listing of Acute Myeloid Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (7) clinical trials

A clinical trial seeking patients for a research study of Treatment Choice (TC), guadecitabine

This Phase 3, randomized, open-label, parallel-group multicenter study of the efficacy and safety of guadecitabine in adults with previously treated AML will be conducted in approximately 20 countries. There will be a 14-day screening period, a treatment period, a safety follow-up visit, and a long-term follow-up period. The study is ...


Patients are needed to participate in a clinical research study evaluating Placebo, gilteritinib for the treatment of Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) / Internal Tandem Duplication (ITD) Mutation, Acute myeloid leukemia

Subjects in CR1 will be approached for this study after induction/consolidation therapy is complete and a decision not to proceed with transplantation is made or a suitable donor could not be identified. Subjects will be randomized in a 2:1 ratio to receive gilteritinib or placebo. Subjects will enter the screening ...


Patients are needed to participate in a clinical research study of Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation to evaluate MEC (Mitoxantrone, Etoposide, Cytarabine), FLAG (Granulocyte colony-stimulating factor (G-CSF), Fludarabine, Cytarabine), LoDAC (Low Dose Cytarabine), gilteritinib

Participants considered an adult according to local regulations at the time of signing informed consent will be randomized in a 1:1 ratio to receive ASP2215 or salvage chemotherapy. Participants will enter the screening period up to 14 days prior to the start of treatment. Prior to randomization, the investigator will ...


A clinical trial seeking patients for a research study for the treatment of Acute myeloid leukemia

This is a Phase III, multicenter, double-blind, randomized study of pracinostat vs. placebo with azacitidine (AZA) as background therapy in patients 18 years of age with newly diagnosed acute myeloid leukemia (AML), excluding acute promyelocytic leukemia and cytogenetic low-risk AML, who are unfit to receive intensive remission induction chemotherapy due ...


A clinical research study of AG-120 (ivosidenib) with Azacitidine, Placebo with Azacitidine for the treatment of AML Arising From Myelodysplastic Syndrome (MDS), Acute myeloid leukemia, Newly Diagnosed Acute Myeloid Leukemia (AML), Untreated AML

Study AG120-C-009 is a global, Phase 3, multicenter, double-blind, randomized, placebo-controlled clinical trial to evaluate the efficacy and safety of AG-120 (ivosidenib) + azacitidine vs placebo + azacitidine in adult subjects with previously untreated IDH1m AML who are considered appropriate candidates for non-intensive therapy. The primary endpoint is Overall Survival ...


A Phase 3 clinical study for patients using Mycophenolate mofetil, methotrexate, Methotrexate (low dose), tacrolimus

Study Design This is a prospective randomized trial to determine the effectiveness of different doses of GVHD prophylaxis on mucositis, engraftment and aGVHD. Study consists of two study groups of 50 subjects each. Group A will receive Tac and MTX (15 mg/m2 day +1, 10 mg/m2 day +3, +6, +11). ...


A clinical research study of IAC regimen, High-dose IA regimen, Intermediate-dose IA regimen

The purpose of this study is to compare the clinical efficacy and safety of IAC regimen and IA regimen as induction chemotherapy for initial diagnosed AML patients. 840 cases are supposed to recruited in 3 years.