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Tobacco Use Disorder Clinical Trials

A listing of Tobacco Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (159) clinical trials

Clinical Trials of Texas, Inc. is conducting a research study on moist snuff tobacco products. Qualified participants receive study-related medical care from a board-certified physician and study product for use during the study.

Phase N/A

Varenicline (Chantix) Treatment for Waterpipe Smoking Cessation

The lack of proven waterpipe smoking cessation interventions makes it important to explore interventions proven effective for cigarette smoking cessation. The investigators hypothesize that Varenicline (Chantix) administrated for 12 weeks is associated with higher sustained quit rate at 12 weeks compared to placebo. The investigators propose to conduct a randomized ...


Comparative Effectiveness of Two Tobacco Cessation Interventions for Employees of Partners HealthCare Inc.

Specific Aim: To conduct a randomized controlled trial among permanent employees of Partners HealthCare, Inc., and their adult dependents, who are current tobacco smokers. The trial will compare two interventions designed to help smokers stop using tobacco: (1) External Coaching Program (Standard Care) and (2) Internal Coaching Program, a chronic ...

Phase N/A

Babies Living Safe and Smokefree

The purpose of this randomized controlled trial is to develop and test the efficacy of a multilevel, multimodal intervention designed to reduce children's exposure to secondhand tobacco smoke (primary outcome) and promote smoking cessation in mothers (secondary outcome). Low-income mothers who smoke and their children will be enrolled from the ...

Phase N/A

Pharmacokinetics of Nicotine Sublingual Tablets Versus Nicorette Lozenge in Healthy Smokers

Objective The primary objective of this study is to determine the pharmacokinetic profile of a single dose of Nicotine Sublingual Tablets, 4 mg (Test Product) versus Nicorette Lozenge 4 mg in healthy adult smokers when administered under fasted conditions. Study Design This is an open-label, pseudorandomized, two-way crossover comparison of ...


TEACH: Technology Evaluation to Address Child Health

The proposed study is a pre- /post-implementation study in a pediatric practice with a control practice designed to test the feasibility and effectiveness of an electronic screening and service delivery tool for three modifiable health risk factors in pediatrics: parental tobacco use, sugar-sweetened beverages consumption, and poor dental care

Phase N/A

Stage Ib Trial of mSMART for Smoking Cessation Medication Adherence

Poor medication adherence (a) results in poorer treatment outcome and (b) accounts for $100 to $290 billion in U.S. healthcare costs annually. Therefore, interventions that target medication adherence are increasingly crucial for patient care and cost-effectiveness. Mobile technologies such as smartphones are increasingly ubiquitous and affordable in the U.S., and ...

Phase N/A

Collection of Airway Blood and/or Urine Specimens From Subjects for Research Studies

This is a protocol to obtain blood, urine and/or airway specimens from normal individuals and individuals with lung disorders in order to carry out laboratory studies looking at genetic expression, gene transfer, infection, proteins, human genes, and to store specimens for future genetic studies. Specimens collected may include blood, urine ...

Phase N/A

New Approaches to Smoking Cessation in Heavy Drinkers

The purpose of the proposed project is to develop and test a 12-week integrated cognitive-behavioral therapy (CBT) intervention for smoking and alcohol (SA) + varenicline (Chantix) among heavy drinking smokers (i.e., CBT for SA). The project involves two phases. In Phase 1, an open-label pre-pilot study of CBT for SA ...


Electronic Cigarettes and Reactivity to Smoking Cues

Tobacco-related illness causes over 5 million deaths per year in the developed world, and most currently available smoking cessation treatments do not effectively enhance long-term cessation outcomes. Reactivity to smoking cues is one factor associated with relapse vulnerability, which is untreated by cessation aids such as NRT. Combining treatments, which ...

Phase N/A