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Alcohol Use Disorder Clinical Trials

A listing of Alcohol Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (19) clinical trials

Distress Tolerance Treatment for Substance Users

Despite recent advances in substance abuse interventions, a large percentage of clients entering residential treatment for substance use will drop out of treatment prematurely, and of the remaining, many will relapse soon after treatment completion. Previous research indicates that an individual's ability to withstand psychological distress is a key factor ...


A clinical trial to evaluate treatments using Placebo Oral Tablet, N-Acetylcysteine, Gabapentin for patients

Bipolar disorder (BD) is the Axis I psychiatric condition most strongly associated with substance use disorder (SUD); diagnostic co-occurrence is particularly high between BD and alcohol use disorder (AUD). Individuals with co-occurring SUD and BD (SUD+BD) have substantially worse clinical outcomes than those with either BD or SUD alone. Nonetheless, ...


Patients are needed to participate in a clinical research study of Bipolar II Disorder, Cannabis Use Disorder, Drug abuse, Bipolar I Disorder to evaluate Placebo Oral Capsule, Gabapentin

Bipolar disorder (BD) is the Axis I condition most strongly associated with cannabis use disorder (CUD); there is a six-fold increase in the prevalence of CUD in individuals with BD relative to the general population. Individuals with co-occurring CUD and BD (CUD+BD) have substantially worse clinical outcomes than those with ...


A clinical trial seeking patients for a research study for the treatment of Drug abuse

This is a single-blind (participants are blinded), pilot study with no therapeutic or diagnostic intent and limited drug exposure. The study will be conducted at Baylor College of Medicine in normal, healthy, and non-drug using male volunteers who have not received the Td vaccination in the past 5 years. The ...

Phase N/A

A clinical research study for the treatment of Alcohol Use Disorder

This pilot project leverages the team's expertise in neurobehavioral assessment and focus on sex differences to examine the potential efficacy of cognitive training in treatment-seeking men and women with alcohol use disorders (AUDs). Specifically, the ask whether cognitive training interventions derived from current methods and conceptual models has differential benefits ...

Phase N/A

A clinical trial to evaluate treatments for patients with Neurocognitive Dysfunction, LIVER DISEASE, Alcohol use, Chronic Inflammation, HIV infection

This proposed study continues a line of research by Doctors Cohen, Cook, Kahler, and colleagues on heavy alcohol use, HIV-associated brain dysfunction, and long-term HIV outcomes. The study will build on our past findings to determine the extent to which marked reductions in alcohol consumption at 30 days and again ...

Phase N/A

A Phase 1 clinical study for patients using Placebo, 125 mg AZD0530, 50 mg AZD0530

To assess the effect of oral AZ D0530 at various doses on neuroimaging parameters associated with various forms of impulsivity mediated through glutamate-dopamine interactions, as ascertained through functional magnetic resonance imaging. -- --NOTE-- AZD0530 dosage of 50mg was discontinued by manufacturer. Adjustments were made to account for the removal of ...


Brain Inflammation and Function in Alcoholism

The abuse of high doses of alcohol is associated with cognitive impairment that in extreme cases can result in dementia. However, the mechanisms underlying the neurotoxic effects of alcohol to the human brain are poorly understood. Here we test the hypothesis that alcohol-induced neuroinflammation contributes to its neurotoxic effects in ...

Phase N/A

HIV & Drug Abuse Prevention for South African Men

South Africa has the highest number of HIV-infected persons of any nation, including 2.4 million men, and from 2002-2011 young men have had a 3% incidence HIV rate that has remained stable. New infections occur later in men than in women, making men in their 20s a target for intervention. ...


Patients are needed to participate in a clinical research study to evaluate Alcohol abuse

The main purpose of this study is to demonstrate the efficacy of two different treatments for inhibitory control improvement (measured by the modified Stop signal task): a behavioral treatment based on Retrieval-Extinction Learning, through the AAT (Alcohol Approach Avoiding Task) and a treatment based on the neuromodulation of prefrontal cortex ...

Phase N/A