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Irritable Bowel Syndrome (IBS) Clinical Trials

A listing of Irritable Bowel Syndrome (IBS) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (71) clinical trials

FMT for Patients With IBS With Fecal and Mucosal Microbiota Assessment

Irritable bowel syndrome (IBS) is a common functional bowel disorder of the gastrointestinal tract affecting up to 20 percent of the adolescent and adult populations (1). It is characterised by abdominal pain, irregular bowel habits, altered stool consistencies and bloating (2), and is associated with impaired quality of life. IBS ...

Phase N/A

Is There Any Correlation Between Plasmatic Zonulin and Expression of Intestinal Tight Junction Proteins in IBS Patients?

The goal of our study is to look for a correlation between plasmatic zonulin and increased colonic permeability (assessed by the expression of intestinal tight junction proteins by western blot) in IBS patients and to look for a role of intestinal low-grade inflammation and microbiota. Population : IBS patients with ...

Phase N/A

Gut Permeability Sensitivity and Symptomatology

To better understand the relationship between gut barrier function and the symptomatology and pathophysiology of IBS.

Phase N/A

Effect of Saccharomyces Cerevisiae on the Improvement of Gastro-intestinal Disorders Associated to IBS With C Phenotype

The main objective is to assess the effect of an 8-week daily supplementation with IbSium (probiotic yeast Saccharomyces cerevisiae CNCM I-3856) on the improvement gastro-intestinal disorders associated to the type C IBS (constipation predominant).

Phase N/A

A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically

The purpose of this study is to determine the amount of linaclotide and its active metabolite (MM-419447) excreted in breast milk after multiple, once daily doses of linaclotide (145 g or 290 g) in lactating women receiving the drug therapeutically.


The Biologic Onset of Crohn's Disease: A Screening Study in First Degree Relatives

Crohn's Disease (CD) is a form of inflammatory bowel disease (IBD) that affects the gastrointestinal tract. CD is a chronic, remitting, and relapsing disease that is rarely diagnosed at or near its biological onset. In routine clinical practice, CD diagnosed at the pre-clinical stage is largely by chance during routine ...

Phase N/A

Moxibustion for Diarrhea-predominant Irritable Bowel Syndrome

A randomized controlled trial Moxibustion treatment, placebo control To observe the safety and efficacy of moxibustion treatment versus placebo control Evaluation by structural MRI and resting state-functional MRI

Phase N/A

The Effect of Coltect (Selenium Curcumin and Green Tea) on Irritable Bowel Syndrome

The etiology of Irritable bowel syndrome is unknown but some evidence suggests it may be caused by a certain degree of inflammation, another theory is that intestinal flora has an influence on IBS. Coltect combines 3 ingredients: green tea, selenium and curcumin, all of which have been shown to have ...


Investigation of Linaclotide's Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients

modulate these mechanisms and thereby improve visceral pain. Investigators propose three specific aims: Examine the hyperexcitability of the afferent-pelvic floor brain axis in 60 patients with IBS by measuring the cortical evoked potentials (CEP) and sensory thresholds after electrical stimulation of the rectum and anus before and after administration of ...

Phase N/A

Traditional Chinese Medicine for Treatment of Irritable Bowel Syndrome

This will be a 10 week randomized, double blind, parallel group, single center study on patients who fulfil ROME III criteria for IBS-Constipation predominant subtype (IBS-C) and TCM syndrome of Liver Qi stagnation.The study will consist of a two week baseline run-in period without medication, an 8 week randomized double ...