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Irritable Bowel Syndrome (IBS) Clinical Trials

A listing of Irritable Bowel Syndrome (IBS) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (80) clinical trials

Culturally Adapted Psychological Intervention for the Management of Irritable Bowel Syndrome (IBS)

A systematic review suggested no overall difference in the rates of IBS in East and West . In a population based study from Pakistan. Prevalence of IBS was assessed using Rome II criteria in relation to psychological distress, disability and life events in men and women separately. The prevalence of ...

Phase N/A

Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)

Methods Sample collection in healthy subjects, IBD and IBS patients: biopsy of rectum and colon descendens blood sample collection collection of sample of nasal mucosa feces collection questionnaires rectal barostat sensitivity measurement transit measurement of colon MR scan of brain

Phase N/A

Efficacy of Low-FODMAPs Dietary Therapy for Irritable Bowel Syndrome in China

Visit 1Enrollment & Screening & Run-in period Patients who meet the inclusion criteria will be asked to complete IBS Baseline Assessment Questionnaires according to Rome III and Rome IV.Subjects that meet the criteria will receive verbal and written information about the study and provide written informed consent. After meeting with ...

Phase N/A

Microbiome Fructan Metabolism and Symptoms in Childhood IBS

Fructans (fructo-oligosaccharides) are a type of carbohydrate which can not be hydrolyzed by humans. It is commonly found in wheat in the American diet. After ingestion they arrive essentially intact into the colon where they are metabolized by the colonic microbiome. Fructan avoidance has been found to help decrease gastrointestinal ...

Phase N/A

Irritable Bowel Syndrome and Low FODMAP Diet

The main objective is to evaluate the efficacy of the FODMAPS diet on IBS symptoms and to correlate the results with the respiratory test

Phase N/A

Confocal Laser Endomicroscopy in IBS Patients

This study will assess dynamic effects of two major antigens on the duodenal mucosa by confocal laser endomicroscopy (CLE). Patients will be blinded to the antigens used (wheat, yeast). Following CLE it is planned to have a cross over exclusion diet with/without the antigens including a washout phase. Furthermore, patients ...

Phase N/A

Ayurvedic Nutritional Counseling for Patients With IBS in Comparison to Conventional Nutritional Counseling

The main goal of this randomized, controlled clinical pilot study is to evaluate the efficacy of an individual Ayurvedic nutritional counseling (according to tradition) compared to an individual conventional dietary advice (according to the German Nutrition Society - DGE) in patients with irritable bowel syndrome. It is to be investigated ...

Phase N/A

fMRI and Visceral Perception Upon Capsaicin Infusion

Brain imaging has shown abnormal brain activations in response to visceral stimulation in patients with the Irritable Bowel Syndrome (IBS). To investigate the possible role of the Nucleus of the Solitary Tract (NTS), the primary relay station in the brainstem for vagal afferents, its activation in IBS and functional dyspepsia ...

Phase N/A

ICBT for Pain-predominant FGIDs in Children and Adolescents: an Implementation Study.

Pain predominant functional gastrointestinal disorders (P-FGIDs) are common in children and adolescents and associated with impaired quality of life. Our research group have previously in a series of efficacy-studies shown that internet-delivered exposure-based CBT leads to reduced symptoms and increased quality of life in children and adolescents with P-FGIDs. There ...

Phase N/A

Measuring Nerve Activity in Small Human Intestinal Biopsies in IBS (Irritable Bowel Syndrome)

Rectal biopsies from IBS patients or healthy subjects will be taken. Biopsies will be used for: the isolation of submucosal plexus to perform: 1.1 live nerve recordings and Calcium imaging; 1.2 immunohistochemistry; 1.3 mRNA (Messenger ribonucleic acids) isolation and real time PCR (Polymerase chain reaction); culturing biopsies On the basis ...

Phase N/A