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Irritable Bowel Syndrome (IBS) Clinical Trials

A listing of Irritable Bowel Syndrome (IBS) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (68) clinical trials

Diets in Symptom Relief and the Influence of Quality of Life in People With Irritable Bowel Syndrome

Subjects who are interested will be interviewed and screened for IBS with Rome criteria by the principle investigator. Research information will be explained in length and consent form will be signed if they agreed to participate Subjects will be blinded and randomly assigned to Conventional IBS diet group (A) or ...

Phase N/A

Pain Relief In Irritable Bowel Syndrome

This is a phase IV, double- blind, randomized, placebo controlled, moncentric study. Males and women over 18 y.o. with Irritable bowel syndrome (IBS) diagnosed applying Rome III criteria will be enrolled consecutively. The study consist of 4 periods: - A screening's period of 2 weeks starting from visit 1, useful ...

Phase

Investigation of Linaclotide's Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients

modulate these mechanisms and thereby improve visceral pain. Investigators propose three specific aims: Examine the hyperexcitability of the afferent-pelvic floor brain axis in 60 patients with IBS by measuring the cortical evoked potentials (CEP) and sensory thresholds after electrical stimulation of the rectum and anus before and after administration of ...

Phase N/A

A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically

The purpose of this study is to determine the amount of linaclotide and its active metabolite (MM-419447) excreted in breast milk after multiple, once daily doses of linaclotide (145 g or 290 g) in lactating women receiving the drug therapeutically.

Phase

Hypnotherapy vs. Probiotics in Children With IBS and Functional Abdominal Pain

Children with irritable bowel syndrome (IBS) or other pain-related functional gastrointestinal disorders (FGIDs) such as functional abdominal pain (FAP) represent a considerable part of visits to pediatric practitioners. These disorders do not only decrease the quality of life but also increase the risk of symptom persistence and comorbid mental issues ...

Phase N/A

Multispectral Optoacoustic Tomography (MSOT) for the Evaluation of Disease Activity in Inflammatory Bowel Diseases (IBD)

The proposed study is designed as a pilot study to evaluate the usefulness of MSOT for the evaluation of disease activity in IBD patients. As current methods for the evaluation of intestinal inflammation in IBD have relevant restrictions, new, non-invasive, quantitative, and accurate modalities are urgently needed. In comparison to ...

Phase N/A

A Long-Term Safety Study of Tenapanor for the Treatment of IBS-C

During the treatment period of up to 39-weeks, subjects will return for study visits approximately every 13 weeks. Subjects will undergo safety assessments at these visits, which may include a physical exam, ECG, vital signs, and clinical labs. Adverse events and concomitant medications will be recorded. Medication compliance will be ...

Phase

A Study to Evaluate Fecal Microbiota Transplantation Engraftment in IBS

This is a randomized pilot study to characterize engraftment of a donor's microflora onto patients with Irritable Bowel Syndrome with diarrhea following fecal microbiota transplantation.

Phase

Effects of HMOs on Faecal Microbiota Gastrointestinal Symptoms Mucosal Immunity and Barrier Function in IBS Patients

The study is a randomised, placebo-controlled, double-blind parallel study in IBS patients. A total of 60 adult patients diagnosed with IBS-C, -D or -A/M according to Rome IV criteria will be included. The participants will be randomized into one of three groups consuming either HMO (two groups) or placebo (one ...

Phase

Irritable Bowel Syndrome (IBS) Functional Magnetic Resonance Imaging (fMRI) With Desipramine

Individuals with irritable bowel syndrome (IBS) may experience abdominal pain as a result of pain signals in the bowel and how these signals are processed in the brain. Studies using brain imaging (pictures) have shown that IBS patients with more pain diagnoses (i.e. fibromyalgia, migraines, etc.) have greater activity in ...

Phase N/A