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Irritable Bowel Syndrome (IBS) Clinical Trials

A listing of Irritable Bowel Syndrome (IBS) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (48) clinical trials

Diets in Symptom Relief and the Influence of Quality of Life in People With Irritable Bowel Syndrome

Subjects who are interested will be interviewed and screened for IBS with Rome criteria by the principle investigator. Research information will be explained in length and consent form will be signed if they agreed to participate Subjects will be blinded and randomly assigned to Conventional IBS diet group (A) or ...

Phase N/A

Hypnotherapy vs. Probiotics in Children With IBS and Functional Abdominal Pain

Children with irritable bowel syndrome (IBS) or other pain-related functional gastrointestinal disorders (FGIDs) such as functional abdominal pain (FAP) represent a considerable part of visits to pediatric practitioners. These disorders do not only decrease the quality of life but also increase the risk of symptom persistence and comorbid mental issues ...

Phase N/A

Multispectral Optoacoustic Tomography (MSOT) for the Evaluation of Disease Activity in Inflammatory Bowel Diseases (IBD)

The proposed study is designed as a pilot study to evaluate the usefulness of MSOT for the evaluation of disease activity in IBD patients. As current methods for the evaluation of intestinal inflammation in IBD have relevant restrictions, new, non-invasive, quantitative, and accurate modalities are urgently needed. In comparison to ...

Phase N/A

Investigation of Linaclotide's Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients

modulate these mechanisms and thereby improve visceral pain. Investigators propose three specific aims: Examine the hyperexcitability of the afferent-pelvic floor brain axis in 60 patients with IBS by measuring the cortical evoked potentials (CEP) and sensory thresholds after electrical stimulation of the rectum and anus before and after administration of ...

Phase N/A

Association Between High Faecal Calprotectin Increased Intestinal Permeability and Visceral Hypersensitivity in IBS-D Patients

Irritable bowel syndrome (IBS) is a common functional disorder which affect around 10% of the general population. Abdominal pain and discomfort are associated with transit disorders (diarrhea, constipation, alternating). IBS is defined by Rome III criteria. For clinicians, IBS remains difficult to treat while its pathophysiology remains not completely understood. ...

Phase N/A

fMRI and Visceral Perception Upon Capsaicin Infusion

Brain imaging has shown abnormal brain activations in response to visceral stimulation in patients with the Irritable Bowel Syndrome (IBS). To investigate the possible role of the Nucleus of the Solitary Tract (NTS), the primary relay station in the brainstem for vagal afferents, its activation in IBS and functional dyspepsia ...

Phase N/A

Subsensory Sacral Nerve Stimulation for Irritable Bowel Syndrome

Twenty four patients with IBS-D or IBS-M according to the ROME III criteria, will be enrolled in the study. Having meet inclusion criteria, the patients are randomised to receive either OFF-subsensory or subsensory-OFF stimulation in a 2+2-week period followed by 2 weeks of suprasensory stimulation. Hereby rendering a percutaneous nerve ...

Phase N/A

Multimodal Stimulation Before and After Sacral Nerve Stimulation for Irritable Bowel Syndrome

Twenty four patients with IBS-D or IBS-M according to the ROME III criteria, will be enrolled in the study. Having meet inclusion criteria, the patients will be examined with Multimodal Stimulation at baseline and at six weeks in the sacral nerve stimulation test period. During the Multimodal Stimulation the patients ...

Phase N/A

Effect of Butyrogenic Fibers in IBS Patients

Despite there being no clearcut advantages, one of the most common recommendations in IBS management is to increase the amount of dietary fibres. In some IBS patients fibres have a deleterious effect on pain and bloating. It has been shown that butyrate can increase colonic sensitivity in rats. Our purpose ...

Phase N/A

The Effect of Probioticson Bloating in IBS

The objective of this study is to establish a model for screening probiotic bacteria in the treatment of meteorism symptoms (feeling of air in the stomach) with otherwise healthy adult women. As excessive bacterial gas production in the intestine is the most likely mechanism behind meteorism, we will examine eventual ...

Phase N/A