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Alcohol Dependence Clinical Trials

A listing of Alcohol Dependence medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (262) clinical trials

Mifepristone Treatment of Alcohol Use Disorder

This is an 8-week, randomized, double-blind, placebo-controlled, 3 arm, parallel groups, dose-ranging study of 1-week of treatment with mifepristone (0, 600, 1200 mg/d) given in conjunction with 8 weeks of manual-guided counseling, and a follow-up visit at Week 12.

Phase

Integrated BA and HIV RR Counseling for MSM With Stimulant Abuse

Project IMPACT targets both stimulant use and sexual risk reduction in effort to help individuals relearn how to enjoy safe but pleasurable activities. The intervention integrates BA, an evidence-based cognitive behavior therapy for improving mood and increasing activity, incorporated with RR counseling aimed to reduce risky sexual practices, and potential ...

Phase N/A

Individualizing Incentives for Alcohol in the Severely Mentally Ill

The objective of this study is to determine whether modifications to a CM intervention improve outcomes and reduce costs in heavy drinkers with serious mental illness using alcohol biomarker ethyl glucuronide (EtG) to test of alcohol abstinence. In CM, patients receive tangible rewards for demonstrating drug abstinence. The investigators propose ...

Phase N/A

Learning to Resist the Urge: Inhibition Training in Abstinent Patients With Alcohol Use Disorders

Therapeutic interventions to treat alcohol use disorders (AUD) still need to be improved. A novel alcohol-specific inhibition-training seems to be a promising new intervention. In this study, recently abstinent patients with AUD attending an inpatient treatment program will be randomly assigned to one of two alcohol-specific inhibition-training groups (varying in ...

Phase N/A

Improving Treatment Outcomes for Prescription Opioid Dependence

Opioid dependence is a serious public health problem, particularly with the dramatic rise in prescription opioid abuse, but long-term opioid agonist maintenance with methadone or buprenorphine (BUP) may not be optimal for many prescription opioid abusers. Yet current opioid detoxification strategies are limited by high relapse rates and/or lack of ...

Phase

Teen Success Project

The overarching purpose of this study is to increase justice-involved youths' access to an evidence-based practice for substance abuse, specifically Contingency Management (CM). This randomized controlled trial will examine the effectiveness of using juvenile probation officers (JPOs) to deliver CM to youth (aged 12-17 years) on their caseloads. CM is ...

Phase N/A

Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging

Objective Functional and structural magnetic resonance imaging techniques have proven essential for noninvasive mapping of brain physiology and pathology. The primary objective of this protocol is to develop advanced magnetic resonance imaging and spectroscopy (MRI and MRS) techniques for neuroimaging studies related to addiction. These neuroimaging techniques will be used ...

Phase N/A

Aripiprazole for Bipolar Disorder and Alcohol Use Disorder

The investigators will conduct a 12-week, randomized, double-blind, parallel-group, placebo-controlled study of aripiprazole in 132 persons with Alcohol Use Disorder (AUD) and bipolar I or II disorder, currently depressed or mixed phase. Primary Aim will be to assess change in alcohol use by the Timeline Followback (TLFB) method. Secondary Aim ...

Phase

Impact of the Systematic Use of the Criteria STOPP/START in Short Stay Geriatric.

Assess the impact of the systematic use of STOPP/START tool during medication conciliation on the evolution of hospitalised elderly people's quality of life at 2 months.

Phase N/A

New Therapeutic Strategies for Inhibitory Control in Alcoholism

The main purpose of this study is to demonstrate the efficacy of two different treatments for inhibitory control improvement (measured by the modified Stop signal task): a behavioral treatment based on Retrieval-Extinction Learning, through the AAT (Alcohol Approach Avoiding Task) and a treatment based on the neuromodulation of prefrontal cortex ...

Phase N/A