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Alcohol Dependence Clinical Trials

A listing of Alcohol Dependence medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (37) clinical trials

Cognitive Task Development and Implementation for Functional MRI Studies

Objective: Drugs of abuse have cognitive and affective effects that may contribute to the inception and maintenance of their use. In order to measure these effects, psychological tests suitable for use both in and outside the fMRI scanner need to be developed and validated. Thus, the objective of this protocol ...

Phase N/A

Study of Structural Imaging

Objective The purpose of this protocol is to characterize cerebellar volumes and function in alcoholics and recovery of cerebellar volume and function during early abstinence. This study also investigates how cerebrocerebellar circuits contribute to cognitive and motor impairment in alcoholism. Study Population Healthy volunteers and Inpatient participants with alcohol use ...

Phase N/A

ADHD: Gaps Between Patients With Alcohol-dependence and Impact on Relapse

Some recent studies have found that adult attention deficit - hyperactivity disorder (ADHD) was frequent among patients with alcohol-dependence. However, no investigation has ever addressed whether ADHD may impact the drinking outcome. Moreover, most of the different aforementioned studies assessed ADHD using the ADHD self-report scale (ASRS). The ASRS is ...

Phase N/A

Study of Familiarity in Alcohol Dependence

Familiarity will be tested by a specific familiarity task using an original paradigm. This paradigm allows the analysis of familiarity as a quantitative process as well as the analysis of personal familiarity to each subject. Three familiar and three unfamiliar faces are morphed in pairs for each participant. The displayed ...

Phase N/A

Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder Via Microbiota Investigations: A Pilot Study

Objective An increasing body of preclinical literature suggests a role of the gut microbiota in a wide range of medical disorders, including neuropsychiatric diseases like autism, anxiety, and depression. Preliminary studies have reported alterations in microbiota composition, inflammation, and intestinal permeability in alcohol-dependent patients. However, there is little research on ...

Phase N/A

Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging

Objective Functional and structural magnetic resonance imaging techniques have proven essential for noninvasive mapping of brain physiology and pathology. The primary objective of this protocol is to develop advanced magnetic resonance imaging and spectroscopy (MRI and MRS) techniques for neuroimaging studies related to addiction. These neuroimaging techniques will be used ...

Phase N/A

Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

Objective: The purpose of this protocol is to obtain a standard set of assessments, including brain behavioral, structural, functional, and connectivity (structural and functional) information, on all NIAAA research participants, referred to hereinafter as Characterization Imaging Instruments (CII); a) to determine how individual differences in brain structure and evoked responses ...

Phase N/A

A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements (CDEs) Into the Electronic Health Record (EHR) in Large Primary Care Settings ("CDE-EHR-PC" Study) Phase 3

SPECIFIC AIMS To program the NIDA CTN CDEs, the NIDA/ASAM electronic Clinical Quality Measure (eCQM), and a lean decision support module into Epic. To study the process of implementation of screening and referral using Epic-driven CDEs and CDS in three primary care clinics / practices, including defining potential barriers and ...

Phase N/A

Developing Field Tools for Real-Time Assessment of Exposure to Psychosocial Stress and Drug Use in an Outpatient Treatment Population

Background. This protocol arose in response to NIH s Genes and Environment Initiative (GEI). There is no genetic component to this protocol (update: no genetics initially but added by amendment in February 2013); rather, the goal is to develop field-deployable measures of environmental influences (stressors, drug exposure, etc.) that can ...

Phase N/A

Maintaining Independence and Sobriety Through Systems Integration Outreach and Networking

Background: Homeless Veterans often have multiple health care and psychosocial needs, including assistance with access to housing and health care, as well as support for ongoing treatment engagement. The Department of Veterans Affairs (VA) developed specialized Homeless Patient Alignment Care Teams (HPACT) with the goal of offering an integrated, "one-stop ...

Phase N/A