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Chordoma Clinical Trials

A listing of Chordoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (6) clinical trials

A Phase II Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma

This is a Phase II, multicenter, open-label, single arm, 2-stage study of tazemetostat 800 mg BID administered orally in continuous 28 day cycles. Screening of subjects to determine eligibility for the study will be performed within 21 days of the first planned dose of tazemetostat. Eligible subjects will be enrolled ...

Phase

Study of Individuals and Families at High Risk for Cancer

OBJECTIVES: - Identify individuals at high risk of cancer, especially due to personal or family medical history. - Evaluate and define clinical spectrum of disease in syndromes predisposing to cancer. - Quantify risks of tumors in family members. - Map, clone, and determine function of tumor susceptibility genes. - Identify ...

Phase N/A

Collecting and Storing Tissue Blood and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma

OBJECTIVES: I. Collect human tumor tissue and other biological specimens (blood, serum, and bone marrow) from patients with rhabdomyosarcoma or non-rhabdomyosarcoma soft tissue sarcoma diagnosed and/or treated at a Children's Oncology Group (COG) member institution. II. Provide a repository for storage of tissue and other biological specimens collected by COG ...

Phase N/A

HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors

Patients with relapsed solid tumors such as sarcomas and neuroblastoma have a poor survival, generally < 20%. There is an urgent need for new treatments that are safe and effective. HSV1716, an oncolytic virus, is a mutant herpes simplex virus (HSV) type I, deleted in the RL1 gene which encodes ...

Phase

Natural History Study of Patients With Central Nervous System Tumors Being Evaluated at the National Institutes of Health

OBJECTIVES: - Evaluate patients with CNS tumors who are probable future candidates for NCI phase I and II protocols. - Follow patients with CNS tumors that are representative of important scientific and/or clinical principles. - Attain a steady flow of patients with CNS tumors at the NIH, which will help ...

Phase N/A

Identifying New Families With Multiple Members Affected by Chordoma

OBJECTIVES: - To determine the feasibility of conducting a larger study encompassing the remaining English-speaking patients at Massachusetts General Hospital with chordoma. - To identify new families with multiple members affected by chordoma to participate in clinical and gene mapping studies. OUTLINE: Patients complete a questionnaire about demographics (education, marital ...

Phase N/A