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Lymphoproliferative disorders Clinical Trials

A listing of Lymphoproliferative disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (16) clinical trials

Family Study of Lymphoproliferative Disorders

Blood and lymph node cancers can begin in either the lymphatic tissues (as in the case of lymphoma) or in the bone marrow (as with leukemia and myeloma), and they all are involved with the uncontrolled growth of white blood cells. There are many subtypes of these cancers, e.g., chronic ...

Phase N/A

Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders

The purpose of this study is to better understand the genetic causes of Hodgkin's disease (a kind of lymphoma) and non-Hodgkin's lymphoma, as well as multiple myeloma, leukemia, and related diseases. The doctors have identified the patient because 1) they have had a lymphoproliferative disorder such as lymphoma, leukemia, or ...

Phase N/A

Establishing a Tumor Bank in Families With Multiple Lymphoproliferative Malignancies

Patients who participate will be asked to complete detailed family and medical history questionnaires initially, with a follow-up questionnaire every year. Patients will be asked to supply a blood sample and possibly a mouthwash sample, both of which can be done by mail. Patients will be asked to consent to ...

Phase N/A

Erythropoietic Protoporphyrias: Studies of the Natural History Genotype-Phenotype Correlations and Psychosocial Impact

The porphyrias are a group of rare metabolic diseases that may present in childhood or adult life and are due to deficiencies of enzymes in the heme biosynthetic pathway. The most common manifestations are related to accumulation of intermediates in the pathway and usually occur as acute neurological attacks (as ...

Phase N/A

Oral Iron for Erythropoietic Protoporphyrias

This is a clinical trial, which means its purpose is to study an intervention or treatment. In this study all patients with EPP or XLP will be given a standard dose of iron pills and monitored for one year. There is currently no effective Food and Drug Administration (FDA) approved ...

Phase N/A

Transfusion-related EBV Infection Among Allogeneic Stem Cell Transplant Pediatric Recipients

All patients will be recruited approximately 1 month before transplantation (before pre-transplant conditioning chemotherapy and pre-surgery evaluation) and followed-up to 1 year post-transplantation. Thus, each subject will be followed-up for a 13-month period. At entry, a questionnaire will document socio-demographic data and pre-transplant clinical indicators such as age, gender, primary ...

Phase N/A

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

OBJECTIVES Primary Evaluate the use of 3'-deoxy-3'-[18F] fluorothymidine (FLT) positron emission tomography (PET) imaging to measure tumor proliferation and the DNA synthetic pathway (thymidine kinase levels) in patients with cancer. Secondary Determine the efficacy of FLT PET imaging in detecting lesions and estimating response to treatment. OUTLINE: Patients undergo up ...

Phase N/A

Registry of Older Patients With Cancer

OBJECTIVES Primary To create a registry (to be called "Carolina Senior") of older patients with an appointment at North Carolina Cancer Hospital. To have these patients complete a Geriatric Assessment (GA). Secondary To measure the response rates of GAs of Carolina Senior patients and their satisfaction with a GA by ...

Phase N/A

Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases

This study is performed in order to investigate the molecular mechanisms of action of photo(chemo)therapy in skin diseases, including psoriasis, cutaneous T-cell lymphoma, other lymphoproliferative disorders of the skin, eczema, lichen planus, prurigo/pruritus, polymorphic light eruption, mastocytosis, graft-versus-host disease, vitiligo and other photo(chemo)therapy-responsive diseases. Twenty patients will be enrolled per ...

Phase N/A

Biomarkers for Post-Transplant Lymphoproliferative Disorders in Children

EBV-associated post-transplant lymphoproliferative disease (PTLD) is the most common malignancy in children after transplant. Diagnosis and effective treatment of the EBV-associated cancer is hampered by our inability to determine which children are at risk of developing these cancers and to detect the cancer at an early stage. In this study, ...

Phase N/A