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Birth Defects Clinical Trials

A listing of Birth Defects medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (13) clinical trials

A clinical trial seeking patients for a research study for the treatment of Craniopharyngioma, Cushing's Syndrome, Pituitary Adenoma, Atresia, Endocrine disorder, CONGENITAL ANOMALY NOS

There are a variety of tumors affecting the pituitary gland; The gene(s) involved in the pathogenesis of these tumors are largely not known; their possible association with other developmental defects or inheritance pattern(s) has not been investigated. The present study serves as a (i) screening/training, and, (ii) a research protocol. ...

Phase N/A

A clinical trial seeking patients for a research study for the treatment of Mental Retardation, Inborn error of metabolism, Smith-Lemli-Opitz Syndrome, Atresia, Hypotonia, CONGENITAL ANOMALY NOS

Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive multiple congenital anomaly/mental retardation syndrome. Typical clinical features include a distinctive facial appearance, mental retardation, autistic behavior, hypotonia, failure to feed, poor growth, decreased life span, and variable structural anomalies of the heart, lungs, brain, gastrointestinal tract, limbs, genitalia and kidneys. The SLOS ...

Phase N/A

Genomic Sequencing and Personalized Treatment for Birth Defects in Neonatal Intensive Care Units

Neonatal congenital malformation is one of the most frequent cause of infant death in the western world and major cities of China. There are many different types of congenital malformations, and some of these can be caused by changes in gene mutation. Next generation sequencing (NGS) is a high-throughput parallel ...

Phase N/A

A clinical research study for the treatment of Hepatitis C virus, CONGENITAL ANOMALY NOS, Pregnancy Complications, Atresia, Hepatitis C

Ribavirin, a nucleoside analog with antiviral activity, is used in combination with interferons or pegylated interferons for the treatment of chronic hepatitis C (HCV). Extensive clinical studies have demonstrated that combination therapy with ribavirin and interferons or pegylated interferons are efficacious treatments for HCV. However, ribavirin has been assigned a ...

Phase N/A

Non-Invasive Determination of Fetal Chromosome Abnormalities

The overall significance of this study is to develop a laboratory developed test (LDT) to use a new marker in the maternal blood to better identify pregnancies that have a child with a chromosome abnormality such as Down syndrome (trisomy 21), Edward's syndrome (trisomy 18), Patau syndrome (trisomy 13), Klinefelter ...

Phase N/A

Pregnancies Complicated by Fetal Anomalies

Repository data will be collected from the medical record and entered into the data base after the patient has completed the appointment. Data collection will continue into the postpartum period for each participant. Data collection will continue for the child during the treatment of the medical condition, up to approximately ...

Phase N/A

Personalized Genomic Research

Recent advances in genomic techniques are making possible a new wave of genetic discovery. We hope to couple genomic techniques with more traditional methods involved in genetic discovery in order to investigate a broad range of conditions for which there is strong evidence that genetic factors are involved. To accomplish ...

Phase N/A

Antiretroviral Pregnancy Registry (APR)-Risk of Birth Defects

The Registry conforms to the FDA Guidance for Industry: Establishing Pregnancy Exposure Registries, the Guidelines for Good Pharmacoepidemiology Practices, and the FDA Guidance on Pharmacovigilance. The Antiretroviral Pregnancy Registry collects data on use of the following GSK drugs: abacavir, amprenavir, delavirdine, fosamprenavir, lamivudine, maraviroc, zidovudine, and their combinations during pregnancy. ...

Phase N/A

BioThrax (Anthrax) Vaccine in Pregnancy Registry

This study will use a convenience sample and passive referral to enroll participants. For the maternal outcome portion of the study, pregnant active duty women who consent to join the registry are expected to complete several surveys over the course of their pregnancy, including an initial enrollment survey, a follow-up ...

Phase N/A

Prenatal Alcohol Biomarker Study in Uruguay

The goal of the proposed research study is to examine the association between maternal alcohol use and newborn phosphatidylethanol (PEth) levels in their newborn children, in a country (Uruguay) where significant alcohol use is common during pregnancy. Maternal alcohol biomarker assays will include ethyl glucuronide (EtG) in hair and nails ...

Phase N/A