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High Blood Pressure (Hypertension) Clinical Trials

A listing of High Blood Pressure (Hypertension) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (155) clinical trials

Type 2 Diabetes After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass: A Randomised Single Centre Study

The Roux-en-Y gastric bypass operation combines restrictive and malabsorptive principles. It is the most commonly performed bariatric procedure worldwide (~ 50 %). Vertical (sleeve) gastrectomy on the other hand, is a purely restrictive procedure and has gained popularity and is now accepted as a valid procedure accounting for approximately five ...

Phase N/A

Effectiveness of Avapro in Obese Normotensive/Hypertensive African Americans

Using a crossover design, we will compare the effects of a placebo to an angiotensin II receptor antagonist on the urinary sodium excretion response in obese normotensive subjects and untreated hypertensive African-Americans subjects. We expect that the urinary sodium excretion response to angiotensin II receptor antagonist therapy will be less ...

Phase

Health Education Using Text Messaging Prevents Hypertension in High Risk People

Prehypertension is a predisposing condition for morbidity in hypertension and cardiovascular diseases. This has been defined as a systolic pressure from 120 to 139 mmHg or a diastolic pressure of 80-89 mm hg. The prevalence of this condition estimated to be at least 2 times higher than hypertension and those ...

Phase N/A

REACH- Reducing Risk With E-based Support for Adherence to Lifestyle Change in Hypertension

Individuals with elevated systolic blood pressure (SBP) are at increased risk for cardiovascular disease (CVD; Risk Ratio, RR = 1.47; 95% CI, 1.24-1.74), stroke (RR, 1.42; 95% CI, 1.03-1.93), coronary heart disease (CHD; RR, 1.44; 95% CI, 1.18-1.77), heart failure (HF; RR, 1.60; 95% CI, 1.15-2.22), and CVD mortality (RR, ...

Phase N/A

The Treatment of Hypertension Associated With Severe Preeclampsia (PE). A Trial of Urapidil Versus Nicardipine

The objective of this study is to demonstrate that urapidil is not inferior to nicardipine for the treatment of hypertension associated with preeclampsia (PE) and that it is better tolerated. - efficacy endpoint : mean arterial blood pressure corrected to 100-120 mmHg after 120 min of study drug administration. - ...

Phase

ADMA Levels in End-Stage Renal Disease

Asymmetric dimethylarginine, ADMA, in plasma, is significantly elevated in patients with renal disease and associated with cardiovascular morbidity and mortality. We found that whole blood (WB) possesses the metabolic pathways required for both the generation and elimination of ADMA and we have developed ex vivo methods to assess the WB ...

Phase N/A

Study of Optimal Treatment Plan in Hypertensives With Anti-AT1-Receptor Autoantibody

The autoantibodies against AT1 receptor (ATR-AA), behaving like an agonist were detected in patients with hypertension. ATR-AA which can blocked by ARB may play a role in the pathogenesis of hypertension. The present study is to explore whether AT1 receptor blocker has superior anti-hypertensive effect in patients with positive ATR-AA ...

Phase

Rajavithi Health Promotion Project (Population Base Cohort)

Metabolic Syndrome (hypertension, diabetes mellitus, obesity, cerebrovascular-cardiovascular disease) In Community Survey was performed in central Bangkok. Prospective Cohort and intensive educated intervention (health promotion program in specific high risk groups) were performed. The aim of the study is to identify high risk patients who can develop serious complications from metabolic ...

Phase

Prevalence of Chronic KIdney Disease in Hypertensive Patients

This will be Cross sectional or prevalent study targeting diagnosed hypertensives aged 40 and above years, in middle to low socio-economic settings of Karachi. This proposed study will be nested in the existing Wellcome Trust funded study. The parent study is designed to determine the impact of a unique community ...

Phase N/A

Oxidative Stress Lowering Effect of Simvastatin and Atorvastatin.

Background HMG-CoA reductase inhibitors (statins) are effective lipid-lowering agents and are known to reduce cardiovascular events. It was initially assumed that cholesterol reduction by statins was the only mechanism responsible for their beneficial effect. However, beneficial effects of statins seem to occur very early in the course of their therapy ...

Phase