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High Blood Pressure (Hypertension) Clinical Trials

A listing of High Blood Pressure (Hypertension) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (425) clinical trials

Chlorthalidone and HCTZ Impacts on Platelet Activation

This will be a randomized, double-blinded, three-period crossover study of platelet activation and aggregation in 30 non-smoking healthy volunteers comparing chlorthalidone (CTD), hydrochlorothiazide (HCTZ), and aspirin (ASA; active control). The study hypothesis is that CTD has different effects on platelet activation and aggregation than HCTZ.


Clinical Trial in Patients With Hypertension and Left Ventricular Dysfunction

The scope of this entire study is to examine the patients as follows:: Complete Echocardiographic Study including the index of left ventricular mass and relative wall thickness (RWT), measurement acquired from left parasternal longitudinal axis. Further assessment will be diastolic function and filling pressures of the left ventricle using all ...

Phase N/A

The Efficacy of a Combination of Telmisartan/S-Amlodipine Compared With Telmisartan Monotherapy

A multicenter, Prospective, Randomized, Open-label, Phase 4 Trial designed to Evaluate the Efficacy of a Fixed Dose Combination of Telmisartan/S-Amlodipine on 24-hour Ambulatory BP Control Compared with Telmisartan Monotherapy


An Efficacy and Safety Study in Children 6 to Less Than 18 Years of Age With Hypertension

The purpose of the study is to evaluate the efficacy and safety of the study drug relative to an active comparator losartan which the same class of drug and is approved for use in the pediatric population aged 6 years and older. Approximately 260 subjects will participate in a 6-week, ...


Effect of Renal Denervation in End Staged Renal Disease With Resistant Hypertension

Hypertension is a major cardiovascular risk factor and numerous treatment strategies have been developed to treat hypertension properly and reduce cardiovascular risk. However, there is a subgroup of hypertension which are resistant to treatment. Resistant hypertension is associated to sympathetic hyperactivity Renal sympathetic nerve is known to be associated with ...


Home-Based Screening for Early Detection of Atrial Fibrillation in Primary Care Patients Aged 75 Years and Older

SCREEN-AF is an investigator-initiated, multicenter, open-label, two-group randomized controlled trial investigating non-invasive, home-based AF screening. The trial targets patients aged 75 years or older with a history of hypertension and without known AF who would be potential anticoagulant candidates if AF were detected. Eligible participants will be recruited from primary ...

Phase N/A


The purpose of this study is to obtain an assessment of the efficacy and safety of renal denervation in the absence of antihypertensive medications.

Phase N/A


The purpose of this study is to obtain an assessment of the efficacy and safety of renal denervation in the presence of three standard antihypertensive medications.

Phase N/A

Myocardial Perfusion Oxidative Metabolism and Fibrosis in HFpEF

The investigators hypothesize that HFpEF is associated with reductions in myocardial blood flow and energy utilization and increased myocardial fibrosis as compared to age and gender matched hypertensive and healthy controls. The investigators will test their hypotheses by comparing measurements of myocardial blood flow, energy utilization, and fibrosis between three ...


Mobile Phone-based Intervention for Promoting Healthy Habits and Weight Loss

The NewMe™ (Eco-fusion, Ltd) is a science driven lifestyle change program for better living ( What's in the program? It starts with two weeks to shakeup the patient. It is focused on ridding the patient of known food addictions and helping the body patient return to its long forgotten normal ...

Phase N/A