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High Blood Pressure (Hypertension) Clinical Trials

A listing of High Blood Pressure (Hypertension) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (33) clinical trials

Do you have HIGH BLOOD PRESSURE? You might qualify to participate in a HIGH BLOOD PRESSURE research study involving an investigational medication.


The primary objective of the study is to explore 4 doses of ACT-132577 on diastolic blood pressure (DBP) in subjects with essential hypertension (grade 1 and 2).


A Phase 2 Trial of IW-1973 A Stimulator of Soluble Guanylate Cyclase (sGC) in Patients With Stable Type 2 Diabetes and Hypertension

To evaluate the impact of escalating doses of IW-1973 on endothelial function [using EndoPAT to measure fingertip small vessel pulse volume], blood pressure (BP), and heart rate.


Effectiveness of Avapro in Obese Normotensive/Hypertensive African Americans

Using a crossover design, we will compare the effects of a placebo to an angiotensin II receptor antagonist on the urinary sodium excretion response in obese normotensive subjects and untreated hypertensive African-Americans subjects. We expect that the urinary sodium excretion response to angiotensin II receptor antagonist therapy will be less ...


Exercise Intervention in Female School Children: Effect on Blood Pressure Body Mass Index (BMI) and Maths Scores

- Primary Objective: To compare the effect of 6 months healthy physical activity on blood pressure in female school children (9-13 yrs) with those who have routine physical activity - Secondary objective: To compare the effect of 6 months of healthy physical activity on body mass index and maths scores ...


Vascular Dysfunction in Human Obesity Hypertension

The purpose of the study is to test the effects of: 1) blocking sympathetic nerve activity with a drug called clonidine, and 2) by blocking a kidney protein called renin, and on blood vessel function and muscle nerve activity in adults who are obese and have high blood pressure. Years ...


Oral Nitrite in Adults With Metabolic Syndrome and Hypertension

Cardiovascular disease remains the leading cause of death in the United States and worldwide. Several studies have demonstrated that fruit and vegetable rich diets significantly reduced blood pressure and reduced the risk of ischemic stroke and cardiovascular disease in general, the exact mechanisms remain poorly understood. Preclinical and clinical research ...


Renal Protection Using Sympathetic Denervation in Patients With Chronic Kidney Disease

Background patients with chronic renal insufficiency are an ideal group for renal denervation (RDN), because of the increase in sympathetic tone. This increase leads to sodium retention, reduction of perfusion of the kidney and to excessive activation of renin angiotensin aldosterone system. The activation of the sympathetic system significantly contributes ...