Home » Clinical Trials »  Search Clinical Trials

Therapeutic Areas:  |  Musculoskeletal  |  Oncology

Search Medical Condition
Please enter condition
Please choose location
 

Bone Neoplasm Clinical Trials

A listing of Bone Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (453) clinical trials

Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma

OBJECTIVES: - Improve the outcome in pediatric patients with low-risk rhabdomyosarcoma (RMS) treated with vincristine and dactinomycin alone. - Evaluate whether the outcome for older patients with standard-risk RMS with favorable features may be improved/maintained by administering a treatment with limited intensity. - Evaluate whether chemotherapy intensity for patients with ...

Phase

18F-NaF PET in Detecting Metastatic Bone Lesion for Patients With Cancer.

Skeletal metastases are the most common cause of morbidity and mortality in patients with malignancy, especially in patients with breast cancer, lung cancer, prostate cancer and head & neck cancer. In patients with lung cancer, bone metastases are present in 20-30% of patient at initial diagnosis (1-2). Accuracy staging bone ...

Phase N/A

Study of Patients With Cancer or Precancerous Conditions

OBJECTIVES: - To follow and evaluate patients, longitudinally with cancer or precancerous conditions referred to the NIH Clinical Center Pediatric Oncology Branch who present with disease manifestations that lend themselves to clinical evaluation and are of unique scientific importance. - To allow, when clinically indicated, patients to receive standard care ...

Phase N/A

Bone Marrow-derived Cells' Contribution to Tumor Formation and Inflammation

Recent experimental studies showed that circulating bone marrow-derived stem cells contribute to the formation of cancers cells. However, it is not clear whether this is applicable to human beings or not. In addition, bone marrow-derived cells are considered to play a significant role in regeneration of inflamed epithelial cells of ...

Phase N/A

Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone

OBJECTIVES: Primary - Compare the frequency and timing of serious related events (e.g., fractures, radiotherapy to bone, hypercalcemia of malignancy, orthopedic surgery, and spinal cord compression) in patients with advanced breast cancer metastatic to the bone treated with bone marker-directed schedule vs standard schedule zoledronic acid. Secondary - Compare the ...

Phase N/A

Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products

Secondary objectives include the following: to obtain and archive blood samples to 1) detect frequency of vector marking in peripheral blood mononuclear cells when clinically or scientifically indicated, such as in the event of participant development of second malignancy, autoimmune disease, hematologic abnormality, or neurologic event, and; 2) To obtain ...

Phase N/A

Zoledronate in Preventing Skeletal (Bone)-Related Events in Patients Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases

This research study is being done to find out if giving zoledronic acid before the cancer spreads to the bone is better or worse than standard treatment. The study will also compare the effects (good and bad) of early treatment with zoledronic acid compared to standard treatment. In this study ...

Phase

Trabectedin for Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma

This study is designed to accommodate individual requests for treatment with trabectedin before the drug becomes commercially available. In regions where trabectedin becomes commercially available and reimbursable in that particular country, an administrative cutoff for further accrual will be set. Subjects with STS who have relapsed following standard of care ...

Phase

Morphine After Radiofrequency Ablation of Painful Bone Metastases in Patients With Cancer

OBJECTIVES: Primary - Measure the efficacy of morphine sulfate at 8 weeks after radiofrequency ablation (RFA) of bone metastases. Secondary - Assess minimum and average pain and analyze use of morphine sulfate before and after RFA. - Determine disease progression by CT scan of bone. - Evaluate the percentage of ...

Phase

Umbilical Cord Blood Transplant Cyclophosphamide Fludarabine Phosphate and Total-Body Irradiation in Treating Patients With Hematologic Disease

PRIMARY OBJECTIVES: I. To determine the one year survival of patients undergoing umbilical cord blood transplantation (UCBT) after a myeloablative preparative regimen consisting of cyclophosphamide (CY), fludarabine phosphate (fludarabine [FLU]), and fractionated total body irradiation (TBI). SECONDARY OBJECTIVES: I. Incidence of transplant-related mortality (TRM) at 6 months. II. Chimerism at ...

Phase