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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (55) clinical trials

A phase 3 study that evaluates the safety and effectiveness of Elagolix in combination with the naturally produced hormone Estradiol for subjects with moderate to severe Endometriosis associated pain.


This is a Phase 3, dose-escalation study designed to evaluate the safety and efficacy of both elagolix 150 mg QD and elagolix 200 mg BID plus E2/NETA (1 mg/0.5 mg) QD over 24 months in the management of endometriosis with associated moderate to severe pain in premenopausal women.


The purpose of this study is to evaluate the incremental benefit of Fractional Flow Reserve (FFR) derived from Coronary Computed Tomographic Angiography (CCTA) (CT-FFR) compared to CCTA with or without stress testing, using invasive FFR as the gold standard for patients with obstructive disease (> 30% and < 90% stenosis).  ...

Phase N/A

Stimgenics Open-Label Post Market Study

This is an open-label prospective, randomized, controlled, multi-center study comparing Stimgenics Spinal Cord Stimulation (SGX-SCS) programming approach to Standard SCS programming approach. Subjects meeting study entrance criteria will be randomized in a 1:1 ratio to one of two study treatment groups: Test treatment group with SGX-SCS programming approach Control treatment ...


Adalimumab Microneedles in Healthy Volunteers

Objective(s) To evaluate the pain, acceptability and local tolerability of intradermal microneedle injection compared to subcutaneous injection in healthy volunteers. To evaluate the safety, pharmacokinetics, pharmacodynamics and immunogenicity of adalimumab after administration using microneedles versus subcutaneous injection in healthy volunteers. To explore the usability of optical coherence tomography, clinical photography, ...


A Study to Characterize Diclofenac's Plasma and Knee Exposure After Application of Diclofenac Gel to the Knee of Subjects With Osteoarthritis That Have a Scheduled Arthroplasty

The study will be performed in Participants diagnosed with OA of the knee who are scheduled for arthroplasty of the knee as a treatment for their OA. Approximately fifty (50) male and female OA participants, who, at the time of screening, are 50 years old, will be randomized in a ...


Quadratus Lumborum Block vs Transversus Abdominis Plane Block for Post-prostatectomy Analgesia

In laparoscopic prostatectomy, overall pain is a conglomerate of three different and clinically separate components: incisional pain (somatic pain), visceral pain (deep intra abdominal pain), and shoulder pain due to peritoneal stretching and diaphragmatic irritation associated with carbon dioxide insufflation. Moreover, it has been hypothesized that intense acute pain after ...

Phase N/A

Chronic Non-Malignant Pain in Cancer Patients at a Supportive Care Clinic

If participant is found to be eligible and agrees to take part in this study, participant will be asked to complete 3 questionnaires about participant's pain, pain level, and what drugs participant takes to treat participant's pain. Participant will also be asked a few questions about tobacco use. These questionnaires ...

Phase N/A

Effects of Different Rehabilitation Programme on Pain Function and AHD in Patients With SPS And Comparison With Healthy Controls

Coordinated motion between the humerus and scapula is required for pain-free arm movement. Rotator cuff and scapulothoracic muscles dynamically control the subacromial space or acromiohumeral distance (AHD).Scapulothoracic muscles need to provide stability and control in a synchronized fashion to facilitate normal scapulohumeral movement. Scapular upward rotation and posterior tilt is ...

Phase N/A

The Effect of Vitamin D3 on Postoperative Pain in Patients Undergoing Craniotomy

A randomized, double blind, controlled trial will be conducted in intensive care unit (ICU) and neurosurgery ward, in Shohada-E-Tajrish hospital,Tehran, Iran. First, patients will be carefully checked for inclusion and exclusion criteria. Then, the eligible patients will complete the consent form for this study. 60 eligible brain tumor patients diagnosed ...

Phase N/A