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Inflammation Clinical Trials

A listing of Inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (238) clinical trials

Study and Treatment of Inflammatory Muscle Diseases

Polymyositis, dermatomyositis and related disorders, also known as the idiopathic inflammatory myopathies (IIM), are an uncommon, heterogeneous group of diseases. This is an omnibus protocol designed to continue our description of this rare group of diseases, further delineate important groups of patients, and obtain useful material for further study of ...

Phase N/A

Evaluation of Patients With Liver Disease

This is a general clinical research protocol to allow for evaluation, investigation and long-term follow up of patients who have an acute or chronic liver disease. The protocol is designed to study the natural history and pathogenesis of various liver diseases such as acute and chronic hepatitis B, C, D ...

Phase N/A

Genetic Linkage Study for Hereditary Pancreatitis

PROTOCOL OUTLINE: This is a genetics study. Blood samples are collected from patients and family members. DNA is extracted from the blood and used for genotypic analysis and linkage analysis. Patients do not necessarily receive the results of the genetic testing and the results do not influence the type or ...

Phase N/A

Study of Arthritis and Related Conditions

This research protocol will recruit patients with arthritis and related conditions for the purpose of screening patients for treatment protocols, and evaluating the natural history of arthritis and related conditions. Patients will be evaluated clinically, radiographically and serologically, and standardized data will be uniformly collected on all patients. Additional imaging ...

Phase N/A

Blood Collection for Research Related to Certain Diseases Involving Blood Vessels

We are evaluating the role of nitric oxide, inflammatory mediators, and endothelial function in inflammatory diseases that involve the blood vessels, such as sickle cell disease, coronary artery disease, pulmonary vascular or advanced lung disease, malaria, and sepsis. The collection of human blood from both patients and healthy volunteers is ...

Phase N/A

Study of Families With Twins or Siblings Discordant for Rheumatic Disorders

Most autoimmune diseases are thought to develop as a result of chronic immune activation and dysregulation after selected environmental exposures in genetically susceptible individuals. Current evidence suggests that the adult and juvenile forms of systemic rheumatic disorders -- defined here as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis ...

Phase N/A

The Safety and Efficacy of a Tumor Necrosis Factor Receptor Fusion Protein on Uveitis Associated With Juvenile Rheumatoid Arthritis

In other studies, TNFR:Fc significantly reduced joint pain and swelling in adult patients with rheumatoid arthritis, and the Food and Drug Administration has approved the drug for that use. Because medicines for arthritis often help patients with eye inflammation, this study will examine whether TNFR:Fc can help patients with uveitis. ...


The Psoriasis Atherosclerosis and Cardiometabolic Disease Initiative (PACI)

Over the past two decades, inflammation has been identified as an important pathogenic process in cardiometabolic diseases (CMD) such atherosclerotic cardiovascular disease (CVD), dyslipidemia, insulin resistance, diabetes and obesity. However, mechanistic links between inflammation and these disease states in humans remain poorly understood. In this study, we propose to utilize ...

Phase N/A

Analysis of Inflammation and Microbiome in Patients With Sinusitis and Asthma

This is a cross-sectional and non-interventional study to investigate mechanisms of disease in patients with asthma who have concomitant chronic sinusitis and/or nasal polyps (upper airway disease). Approximately 160 participants will be enrolled. Patients who are scheduled to undergo inpatient or outpatient endoscopic sinus surgery at the University of California ...

Phase N/A

Transcutaneous Electrical Vagus Nerve Stimulation to Suppress Atrial Fibrillation

Atrial fibrillation (AF) is the most common cardiac arrhythmia. In previous experimental studies, the investigators found that low-level vagus nerve (VN) stimulation (LLVNS), at voltages substantially below that which slowed the sinus rate, significantly suppressed AF inducibility and decreased AF duration. The investigators subsequently developed a non-invasive neuromodulatory therapy, in ...

Phase N/A