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Inflammation Clinical Trials

A listing of Inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (28) clinical trials

Probiotic Visbiome for Inflammation and Translocation in HIV II

Modern antiretroviral therapy (ART) has transformed the clinical care and lived experience of HIV infection. However, increased rates of adverse health conditions that are related to immune activation, such as cardiovascular disease (CVD) and neurodegenerative disease in ART-treated individuals persist. An important cause of this inflammation is the gut CD4 ...

Phase

Effects of Phytonutrients on Vascular Health and Skin in Obese Males

The proposed investigation has two major objectives: 1. to determine the clinical efficacy of pomegranate juice to reduce skin aging by assessing UV-induced change and skin biological characteristics of elasticity, sebum, hydration/moisture and systemic inflammation and 2. To determine the impact of pomegranate polyphenols on the metabolic response to a ...

Phase N/A

Investigating the Effect of Continuous Positive Airway Pressure on the Neuropathology of Obstructive Sleep Apnoea

This is a prospective, observational physiological study, which is anticipated to last for 4 years. It has been calculated that a minimum of 14 patients with untreated OSA will be studied. In order to study the mechanism of cognitive dysfunction in OSA, participants will start Continuous Positive Airway Pressure (CPAP) ...

Phase N/A

Dried Plums Prevent Inflammation And Improve Bone Health in Osteopenic Men

Osteoporosis in men is an important yet an understudied debilitating disease. To date, most therapies are directed towards postmenopausal osteoporosis, and the efficacy of these therapies is not established for male osteoporosis. Therefore, due to concerns regarding the increasing prevalence of male osteoporosis and minimal treatment options available, it is ...

Phase N/A

Effect of Zinc and Selenium Supplementation on HIV+ Individuals on Antiretroviral Treatment.

HIV-infected individuals on antiretroviral treatment have lowest risk of AIDS events and more life expectancy. However, antiretroviral treatment does not fully restore the immune system in all individuals due to persistent immune activation and inflammation, increasing the risk of non-AIDS complications, such as insulin resistance, diabetes, hypertension, dyslipidemia, obesity, low ...

Phase N/A

Gene Expression Outcomes in Interventions for Substance Using HIV+ Minority Men

This is a pilot study of a new 9-session individually delivered cognitive behavioral intervention targeting sexual minority stress. In this study, 40 HIV+ men sexual minority men will be recruited for the study then will be randomly assigned to either the new 9 session intervention or a writing task condition.

Phase N/A

Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy

Benign prostate hypertrophy (BPH) and inflammation are common non-cancerous enlargement of the prostate, which result in urinary interference and incomplete drainage of the bladder. Compression of the urethra is common cause of such resistance of full draining, and may over time result in progressive hypertrophy, instability, urgency, nocturia and weakness ...

Phase

The Acute Effects of an Isometric Loading Intervention on Lower Extremity Landing Biomechanics in Individuals With Patellar Tendinopathy

The purpose of this study is to determine differences in lower extremity landing biomechanics and real-world physical activity between individuals with patellar tendinopathy compared to individuals without patellar tendinopathy,and to determine the acute effects of an isometric loading intervention on lower extremity landing biomechanics in individuals with patellar tendinopathy.

Phase N/A

Influence of Dietary Nitrate on Vascular Dysfunction and Inflammation

We wish to determine in a prospective manner whether inorganic nitrate affects the endothelial dysfunction induced by systemic inflammation. At baseline we will measure flow-mediated dilatation (FMD) and peripheral augmentation index, as well as aortic stiffness, as measured by pulse wave velocity (PWV). Volunteers will then receive ~8 mmols of ...

Phase

Possible Links Between Inflammation and Lipid Metabolism

Sepsis is a severe clinical syndrome with still limited means of therapy and often poor prognosis. It has been recognized lately that sepsis and inflammation has an important impact on lipid metabolism and that the extent of hypocholesterolemia may even be a marker of severity of illness. This study aims ...

Phase N/A