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Acute Pain Clinical Trials

A listing of Acute Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (80) clinical trials

A Study to Compare the Titration Efficacy and Safety of Control-released Oxycodone and Immediate-released Oxycodone in Patients With Moderate to Severe Cancer Pain

This is an interventional, open label, randomized controlled study carrying in multi-centers. Eighty opioid-naive patients with moderate to severe cancer pain ( 4) in outpatient department (OPD), who agreed and signed informed consent will be randomly assigned in a 1:1 ratio to receive CR + IR oxycodone or conventional IR ...


Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients

A prospective randomized, double blinded trial of ketamine use in adult and elderly blunt trauma patients with associated rib fractures admitted to the trauma service will be conducted. Examples of blunt mechanisms include assault, falls, motor vehicle collisions, motorcycle crashes, motor vehicle pedestrian collisions, crush injuries, and bicycle accidents. The ...


Intranasal Sufentanil Versus Intravenous Morphine for the Management of Acute Pain

This study will be a single-center, randomized, controlled trial conducted in the Brooklyn Hospital Center's Emergency Department (ED) Intervention Study participants will be randomized to receive one of the two study treatments below: Treatment A: Sufentanil 0.7 mcg/kg IN x 1dose (max of 1 mL administered per nostril) Normal saline ...


Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.

The purpose of this study is to determine if there is a difference in patient outcomes with general anesthesia versus spinal anesthesia when given in addition to popliteal and adductor canal nerve blocks for foot and ankle surgery. Popliteal and adductor canal nerve blocks are injections of local anesthetic agents ...


Acetaminophen and Post Circumcision Pain Control

All subjects and controls will be nil per os (NPO) ONLY 30 minutes post procedure, not before the procedure. Due to the cortisol collection requirements, infants will remain NPO 30 minutes post the procedure to ensure accurate levels, per manufacturer protocol. All infants will undergo a standardized circumcision using a ...


Moderate Versus Deep Procedural Sedation With Propofol in the Emergency Department

Purpose: For the pilot phase, if the visual memory assessment test developed in this study can adequately assess periods of amnesia during the procedure, then it can be used for the phase of the study that randomizes patients to moderate or deep sedation. The purpose of the randomized phase is ...


Effectiveness of Intranasal Versus Intravenous Fentanyl in Preterm and Term Newborns for Pain Prevention

Neonatal intensive care unit patients undergoes many painful procedures during their hospitalization. Effective pain control in such procedures as intubation, catheterization, central line insertion, chest tube insertion, etc. is an important part of treatment. Opioids administration is a common practice for acute pain prevention. Fentanyl is the preferred opioid due ...


Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery

Study Design: Prospective study of 58 subjects undergoing elective Lumbar Spinal Fusion (1-3 levels- posterior approach) at UTSW Zale Lipshy University Hospital with: Continuous Lumbar Epidural Analgesia (Patient-Controlled Epidural Analgesia- PCEA groups) Intravenous Patient-Controlled Analgesia (IV PCA) Study Interventions - The intervention to be evaluated in this study is epidural ...


Clinical Pharmacogenetic of Ibuprofen After Lower Third Molar Surgeries

The aim of this study will be to assess the link between the different haplotypes of CYP2C8 and CYP2C9 genes and the clinical efficacy of ibuprofen after lower third molar extractions regarding pain, swelling and trismus, adverse reactions, the amount of pain medication used, the patient satisfaction with the drug ...