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Acute Pain Clinical Trials

A listing of Acute Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (522) clinical trials

Effect of Delta-9-Tetrahydrocannabinol on the Prevention of Chronic Pain in Patients With Acute CRPS (ETIC-Study)

Recent animal data suggest that the endocannabinoid system is a promising target in the prevention of chronic pain. It has been shown that the endocannabinoid system modifies excitatory and inhibitory currents in structures involved in the development of chronic pain such as the amygdala. CRPS is a neuropathic pain condition, ...


Use of the Cannabinoid Nabilone for the Promotion of Sleep in Chronic Non-Malignant Pain Patients

Rationale: The current evidence suggests a sleep promoting effect of THC. Although, there is some support from pre-clinical and small sample size human studies suggesting a direct sleep enhancing effect, it remains unclear from the larger clinical trials, whether improved sleep is an epiphenomena secondary to improvements in the primary ...


Analgesic Efficacy of Testosterone Replacement in Hypogonadal Opioid-Treated Chronic Pain Patients: A Pilot Study.

Opioids are increasingly used for the treatment of non-malignant chronic pain with as many as five to ten million patients treated at the time of the most recent estimate in 2002. The side effects of opioids such as fatigue, loss of libido, Impaired cognition and sexual dysfunction have long been ...


Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia

Critical limb ischemia (CLI) is the end stage of peripheral arterial disease in the legs and is a consequence of deteriorating blood flow supply to the lower limbs. The clinical definition of CLI includes peripheral arterial disease and recurrent rest pain for at least two weeks with or without ulcers ...


Acupuncture in Reducing Ileus in Patients Who Have Undergone Surgery for Colorectal Cancer

OBJECTIVES: Primary - Determine whether a phase III study of acupuncture for postoperative recovery after colorectal surgery is warranted, as defined by evidence of reduction of postoperative ileus in patients who undergo acupuncture vs sham acupuncture after segmental or subtotal colectomy with primary anastomosis for colorectal cancer. Secondary - Determine ...


Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone

OBJECTIVES: Primary - Compare the frequency and timing of serious related events (e.g., fractures, radiotherapy to bone, hypercalcemia of malignancy, orthopedic surgery, and spinal cord compression) in patients with advanced breast cancer metastatic to the bone treated with bone marker-directed schedule vs standard schedule zoledronic acid. Secondary - Compare the ...

Phase N/A

Advantageous Predictors of Acute Coronary Syndromes Evaluation (APACE) Study

Background: The triage of patients with suspected acute coronary syndrome in the emergency room is a time-consuming diagnostic challenge. Triage and management of patients with low probability of coronary artery disease often cause excessive hospital costs. Therefore high sensitive early markers for myocardial damage are needed for more rapidly rule ...

Phase N/A

Coronary Computed Tomographic Angiography in Emergency Department Chest Pain Patients at Intermediate Risk of Acute Coronary Syndrome

Justification: Acute coronary syndrome (ACS) is the clinical manifestation of acute myocardial ischemia induced by coronary artery disease (CAD). Although most patients presenting with chest pain to the Emergency Department (ED) can be stratified into "high risk" or "low risk" chest pain algorithms, patients at "intermediate risk" are more difficult ...


Use of Sedation and Local Anesthesia in Meatotomy: A Prospective Comparison Study

Background- Meatal stenosis requiring surgery occurs more often in circumcised than in uncircumcised boys, with an estimated rate of 7.3%. At our institute, meatotomy is usually performed under general anesthesia and penile block is routinely added after induction. Recently, several reports have described the performance of meatotomy as an office ...


Perioperative Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery

Participants undergoing spine surgery will be randomized into one of three groups;General 1) Anesthesia and postoperative Patient Controlled Analgesia and placebo IV infusion,2) General Anesthesia plus perioperative intravenous lidocaine infusion and post operative patient controlled analgesia or 3) General Anesthesia plus postoperative epidural analgesia plus placebo IV infusion. After surgery, ...

Phase N/A