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Low Blood Pressure (Hypotension) Clinical Trials

A listing of Low Blood Pressure (Hypotension) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (32) clinical trials

Fentanyl Effect on Blood Pressure in Elderly Patients After Induction of General Anesthesia

This is a prospective double-blinded randomized controlled trial (RCT) where patients will be assigned randomly by the investigational pharmacist. Patients will be assigned to one of three groups: (1) A control group that receives 0.9 mcg/kg sodium chloride (NaCL), (2) a fentanyl group that receives 1 mcg/kg fentanyl, or (3) ...


The Prevention of Hypotension After Epidural Analgesia After Major Surgery

Participants undergoing epidural analgesia to treat perioperative pain associated with major surgery will be approached for their willingness to participate in the study. Participants undergoing major thoracic, abdominal, or orthopaedic surgery for whom thoracic or lumbar epidural block would be indicated and planned for intraoperative and postoperative analgesia as per ...

Phase N/A

Esmolol to Treat the Hemodynamic Effects of Septic Shock

Septic shock is a leading cause of death around the world, with a mortality that often ranges 30-50% but in some locations may be even higher. Despite advances in critical care medicine over the last several decades, few therapeutic interventions have demonstrated mortality benefit in this population besides antimicrobial medications, ...


Treatment of Post-SCI Hypotension

Baseline Testing: Subjects will visit the testing laboratory on the SCI Rehabilitation Unit for baseline data collection, prior to initiation of the treatment protocol. Upon arrival, subjects will be placed in the supine position on an adjustable surface for instrumentation, which will be conducted in a quiet, dimly lit, thermo-neutral ...


Impact of Permissive Hypotension on End-organ Damage in the Elderly

Background When it is severe, hypotension compromises tissue perfusion and organ function, leading to multiple organ failure and death. Commonly in intensive care units (ICUs), excessive vasodilation causes hypotension. In response, clinicians administer vasopressors to induce vasoconstriction and thereby raise blood pressure. However, these medications may reduce blood flow to ...

Phase N/A

Biomarkers Blood Pressure BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery

Hypothesis and purpose This study is based on the hypothesis that normal preoperative cardiac biomarkers, lack of intraoperative hypotension and BIS values between 45-60 are associated with better outcomes compared with elevated biomarkers, intraoperative hypotension and/or BIS values below 45. Additionally, the investigators hypothesize that tight blood pressure management reduces ...

Phase N/A

Decision Support for Intraoperative Low Blood Pressure

Blood pressure management is an important part of anesthesia. Many factors contribute to a change in blood pressure during a surgical procedure, such as blood loss, manipulation by surgeons, and there are several mechanisms through which anesthesia itself changes blood pressure. Although a high blood pressure also occurs during anesthesia, ...

Phase N/A

Echocardiography Based Algorithm for Spinal Anaesthesia

Aims and Objectives: Primary aim: To compare an echocardiography based algorithm of hemodynamic management as compared to standard practice in decreasing the incidence of spinal hypotension (number of patients developing a decrease in MAP >20% of baseline or MAP <60 mm Hg). Secondary aims: To compare the number of episodes, ...

Phase N/A

Preventive Effect of Leg Wrapping Combined With Trendelenburg Position on Hypotension Induced by Propofol

** Study procedure check baseline blood pressure ( systolic, diastolic, mean) and heart rate. apply pre-defined measures to each group(arm) ( summarized in arms and interventions section ) induction using propofol 2mg/kg After bispectral index (BIS) goes below 60 & patient become unconsciousness, inject rocuronium 0.6mg/kg intubate patient between 3 ...

Phase N/A

Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs

Patients taking angiotensin converting-enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) are susceptible to hypotensive events during general anesthesia. The purpose of this study is to determine if the use of either methohexital or propofol general anesthesias is more likely to result in hypotensive events in these patients during their ...

Phase N/A