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Proteinuria Clinical Trials

A listing of Proteinuria medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (122) clinical trials

Diabetics are at a higher risk for chronic kidney disease since high blood sugar levels caused by diabetes damage blood vessels in the kidneys. If the blood sugar level remains high over many years, this damage gradually reduces the function of the kidneys. Your kidneys filter wastes and excess fluids ...

Phase

The purpose of the study is to evaluate whether or not atrasentan is effective in delaying the worsening of kidney disease by comparing the time to serum creatinine doubling or the onset of end stage renal disease in patients with Type 2 diabetes and kidney disease.

Phase

NYU Winthrop Hospital Clinical Trials Center is seeking research participants who are 18 years old or older, who are pregnant and between 28 and 37 weeks gestation and are interested in participating in a clinical trial.  Participants will be asked to provide blood and urine sample(s) to be used to ...

Phase N/A

Preeclampsia is a complication of pregnancy. Preeclampsia may occur from 20 weeks’ pregnancy through the delivery and postpartum period.  Preeclampsia does not occur in every pregnant woman. It is thought that preeclampsia occurs in about 3 to 5 out of a total of 100 pregnant women. A higher number of ...

Phase N/A

Effects of Dapagliflozin in Non-diabetic Patients With Proteinuria

Despite optimal treatment with renin-angiotensin-aldosterone-system (RAAS) inhibitors, many patients with non-diabetic kidney disease show progressive kidney function loss, which is associated with high residual proteinuria. Novel treatment strategies are therefore required to further decrease proteinuria and to slow kidney function decline. Dapagliflozin is a sodium-glucose transport (SGLT2) inhibitor and inhibits ...

Phase

Preventing Sickle Cell Kidney Disease

Feasibility Trial of Losartan to Correct Abnormal Circadian Blood Pressure. Cohort participants (below) identified with in-clinic hypertension and abnormal nocturnal dipping on 24 hour ABPM will be asked to participate in a feasibility trial of losartan. Participants will be offered a consultation with Pediatric Nephrology prior to study enrollment. Participants ...

Phase

Response to Anti-hypertensives in Pregnant and Postpartum Patients

Hypertensive disease in pregnancy is a major cause of maternal morbidity and mortality. This condition is responsible for about 12% of the maternal deaths in the United States. Currently, if pregnant patients present with severe hypertension they are either given IV labetalol, IV hydralazine of nifedipine based on individual provider ...

Phase

Sleep Apnea Syndrome in Obese Women During Pregnancy

Excess weight or obesity is associated with an increased risk of health disorders: high blood pressure, diabetes, cardiovascular risks, dyslipidemia and sleep apneas. During pregnancy in obese women, the risk of preeclampsia increases by three and the risk of fetal death in utero by five. Snoring and Obstructive sleep apnea ...

Phase N/A

LimPrOn: Limburg Pre-eclampsia Investigation

Background Multiple adaptations at the cardiovascular system occurs during pregnancy. In the pregnancy condition pre-eclampsia (PE), this adaptations are abnormal. Five to eight percent of all pregnant women worldwide will develop PE. PE is a pregnancy condition which is characterized with a high blood pressure (>140/90 mm Hg) and the ...

Phase N/A

Spironolactone & RAAS: Effect on Urinary Proteinuria & Mean Epidermal Growth Factor Receptor

Determine the safety and efficacy of combination drug therapy in under-represented populations and to evaluate the efficacy of current clinical practices that involve the treatment of diabetic nephropathy with a combination of Angiotensin-Converting-Enzyme (ACE) inhibitors and mineralocorticoid receptor antagonists(MRA). The trial that will examine the safety and efficacy of combination ...

Phase