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Oral Cancer Clinical Trials

A listing of Oral Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (117) clinical trials

BAY 1217389 is a potent and highly selective inhibitor of monopolar spindle 1 (MPS1) kinase activity. Human MPS1 is a serine threonine kinase, which functions as a core component of the spindle-assembly checkpoint (SAC), a key surveillance mechanism that monitors the attachment of spindle microtubules to the kinetochores of the ...

Phase

This study evaluates the efficacy of TAK-385 for achieving and maintaining testosterone suppression. Evaluates the safety and tolerability of TAK-385, evaluates the efficacy for prostate specific antigen (PSA) lowering. This study also evaluates the quality of life related to androgen deprivation and recovery from androgen deprivation therapy using validated patient-reported ...

Phase

MGCD265 belongs to a new class of drugs with anticancer potential, known as tyrosine kinase inhibitors. MGCD265 was shown to slow down the growth of human cancer cells in mice. Clinical studies are being pursued to evaluate the safety of MGCD265 in cancer patients. In this study, MGCD265 is orally ...

Phase

A placebo-controlled study comparing an oral drug ODM-201 versus placebo for men with non-metastatic castrate resistant prostate cancer that have a rising PSA and at high risk for developing metastatic disease.

Phase

People with oral mucositis and head and neck cancer are asked to participate in a research study being conducted by Montefiore Medical Center.

Phase N/A

Xerostomia Pilot Fudan: Acupuncture for Prevention of Radiation-Induced Xerostomia

Acupuncture is the use of very thin needles that are stuck in your skin at certain areas of the body, acupuncture is believed to affect bodily function. Screening Tests: Signing this consent form does not mean that you will be able to take part in this study. You will have ...

Phase N/A

Dose-escalation Study of Oral CX-4945

Elevated CK2 activity has been associated with malignant transformation and aggressive tumor growth and overexpression of CK2 has been documented in multiple types of cancer. CK2 has emerged as a potential anticancer target and inhibition of CK2 represents a potential therapeutic strategy to target a specific molecular defect perpetuating many ...

Phase

p53 Gene Therapy for Head and Neck Malignant Tumors in Advanced Stage

Primary objectives of this study is to determine the efficacy profiles of rAd-p53 intra-tumor injection alone, with concurrent chemotherapy, with concurrent radiotherapy, or combination with surgery for treatment of head and neck malignant tumors in advanced stage (stage III or IV) including target lesion complete response rate (LCR) and overall ...

Phase

Biomarkers in Tissue Samples From Patients Who Have Undergone Neck Dissection for Oral Cancer

OBJECTIVES: - To test preliminary data from node-positive oral squamous cell carcinoma (OSCC) signatures for their ability to predict lymph-positive primaries using a cohort of OSCC tumors. - To perform lymph node prediction using sentinel lymph node-biopsied primaries. - To validate the preliminary data node-positive OSCC signature and test its ...

Phase N/A