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Infantile Spasms Clinical Trials

A listing of Infantile Spasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (5) clinical trials

Prednisolone Versus Vigabatrin in the First-line Treatment of Infantile Spasms

Background and Rationale for the study: Infantile spasms (IS) is a rare, catastrophic age-specific epilepsy syndrome with onset within the first 12 months of life. The disorder is characterized clinically by epileptic spasms, often accompanied by developmental regression and a characteristic interictal electroencephalography (EEG) pattern called hypsarrhythmia. When all these ...

Phase

Trial of Cannabidiol (CBD; GWP42003-P) for Infantile Spasms (GWPCARE7)

This trial consists of 3 parts: a pilot safety phase, a pivotal randomized controlled phase, and an open-label extension phase. The pilot phase only will be described in this record. 2 cohorts of 5 participants will be enrolled sequentially. All participants will receive GWP42003-P.

Phase

A Phase 2 Study of Radiprodil in Subjects With Drug-resistant Infantile Spasms (IS)

The study is divided into 3 parts: Part A - exploratory, Part B - confirmatory, Part C - open label extension

Phase

A Study to Assess the Efficacy Safety and Tolerability of Cannabidiol Oral Solution With Vigabatrin as Initial Therapy in Participants With Infantile Spasms

The primary objective of this study is to evaluate the efficacy of Cannabidiol Oral Solution as adjunctive therapy with vigabatrin as initial therapy in treating participants with Infantile Spasms. The secondary objectives for this study are to evaluate the continued efficacy of Cannabidiol Oral Solution after the 14-day treatment with ...

Phase

A Novel Approach to Infantile Spasms

This is a prospective randomized trial comparing 3 treatment arms: Cosyntropin Injectable Suspension, 1 mg/mL Vigabatrin Combination of both these therapies, Cosyntropin Injectable Suspension, 1 mg/mL and vigabatrin for treatment of new onset infantile spasms. Outcome measures include resolution of clinical spasms, improvement of hypsarrhythmia as well as longer term ...

Phase