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Digestive System Neoplasms Clinical Trials

A listing of Digestive System Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (77) clinical trials

A Study of FPA144 Combined With Modified FOLFOX6 in Gastric/Gastroesophageal Cancer

Phase 1 is an open-label dose-escalation of FPA144 in combination with mFOLFOX6. Eligible patients will have unresectable locally advanced or metastatic GI cancer of any type and be candidates to receive at least 2 doses of mFOLFOX6 chemotherapy. FGFR2 status is not a requirement for enrollment. FGFR2 status will be ...

Phase

Development of Clinical and Biological Database

Implementation of a translational research project is part of the Cancer Plan 2014-2019 and its axis 5 "Advancing clinical and translational research in oncology", and more precisely Action 5.1. The national health strategy launched by the Minister of Health and the Minister of Research will allow a better integration between ...

Phase N/A

Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 1

This Phase I dose escalation study will evaluate Procaspase Activating Compound-1 (PAC-1), a small molecule that activates procaspase -3 to caspase-3, resulting in apoptosis of cancer cells, in patients with advanced malignancies. PAC-1 is taken orally on days 1-21 of a 28-day cycle. The maximum tolerated dose (MTD) of PAC-1 ...

Phase

Standard Care Alone or With Acupuncture for CIPN in Breast Cancer and Multiple Myeloma

Chemotherapy Induced Peripheral Neuropathy (CIPN) is a significant clinical challenge for patients receiving specific chemotherapy regimen (e.g. taxanes and Bortezomib) and critically, if severe, CIPN can lead to the discontinuation of life prolonging treatment. CIPN poses a major problem for patient care as standard pharmacological treatments for CIPN have been ...

Phase

Registry of Endocrine Tumors (Thyroid Parathyroid Adrenal Endocrine Pancreas Endocrine Digestive Tube)

The EUROCRINE project aims to decrease morbidity and mortality of rare endocrine tumours, by means of a pan-European database. Recording and accessing data at the European level, makes it possible to identify these tumours, which cannot be distinguished at local or national level, because of their extreme rarity. Dissemination of ...

Phase N/A

Comparison of Thromboembolic Events Between Enoxa and Lovenox in Patients Undergoing Digestive Cancer

Comparative study with two arms versus ENOXA® LOVENOX®, randomized, prospective, single-center, with rater-blinded whose main objective is to compare the incidence of thromboembolic events (symptomatic and asymptomatic) between the two arms of the study, in patients undergoing digestive cancer and receiving thromboprophylaxis based SODIUM enoxaparin.

Phase

Oxaliplatin in PIPAC for Nonresectable Peritoneal Metastases of Digestive Cancers

Current curative treatment of digestive peritoneal carcinomatosis consists of complete cytoreduction surgery associated with intraperitoneal chemotherapy. This treatment has important limits: a high morbimortality and the impossibility of repeating the sessions. The majority of patients are therefore treated with systemic chemotherapy, which despite its progress, remains palliative. Pressurized Intraperitoneal aerosol ...

Phase

Clinical Trial of Electroacupuncture Stimulation on Prevention and Treatment of Oxaliplatin Neurotoxicity

The clinical trail of electroacupuncture combined with oxaliplatin regimen on gastrointestinal carcinoma.This trail is randomized controled.Patients are diagnosed gastrointestinal cancer based on pathology or cell biology.They are randomized into 2 groups:both groups receive Oxaliplatin regimen.The treatment group receives electroacupuncture in addition to the chemotherapy.The control group only receive the same ...

Phase N/A

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

This is a Phase 1, open-label, single center, randomized study to assess the safety and tolerability of 3 different dose regimens of entinostat in combination with pembrolizumab in patients with advanced solid tumors who previously completed Study SNDX-275-0140 (NCT02897778). Up to 30 patients will be randomized in a 1:1:1 fashion ...

Phase

DC-CIK Combined With TACE in the Treatment of Hepatocellular Carcinoma

60 patients with Hepatocellular Carcinoma, who had received Transcatheter Arterial Chemoembolization (TACE) , will be randomly divided into group A (receive DC-CIK+ TACE treatment) or group B (just receive TACE), and the randomize ratio will be 1:1.

Phase