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Sleep Apnea Syndromes Clinical Trials

A listing of Sleep Apnea Syndromes medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (139) clinical trials

The purpose of the study is to evaluate the response to pain medication in participants with both treated and untreated obstructive sleep apnea. This study will last about 3 weeks. There are 2 to 3 study visits. Total participation will take about 5.5 hours. There will be a home sleep ...

Phase N/A

The purpose of this study is to obtain additional long-term safety and efficacy data on the use of Inspire therapy.

Phase

The purpose of this research study is to determine whether Lemborexant, an investigational medication, decreases the peripheral oxygen saturation (amount of oxygen in the blood) during sleep time in adult subjects with mild OSA (AHI ≥5 to <15) after taking Lemborexant compared with a placebo. This study is comprised of ...

Phase

Treatment Resistant Depression and Obstructive Sleep Apnea Effect of Continuous Positive Airway Pressure (CPAP)

Primary objective: What is the effect on mood and anxiety symptoms of adding CPAP to the psychiatric treatment of patients with TRD and associated OSA? Secondary objectives: How common is co-morbid OSA in patients with treatment resistant unipolar depression referred to a tertiary Mood Disorders Clinic? Is there a difference ...

Phase N/A

AT1R Blockade and Periodic Breathing During Sleep in Hypoxia

Objective: To determine the effects of angiotensin-II, type-I receptor (AT1R) blockade on the relationship between ventilatory control and sleep disordered breathing (SDB) following a night of hypoxic sleep in healthy humans. Justification: Ventilatory adaptation to hypoxia is one of two major adaptations permitting humans to acclimatize successfully to high altitude. ...

Phase

Comparison of Sleep Apnea Assessment Strategies to Maximize TBI Rehabilitation Participation and Outcome

Background and Significance: Meta-analyses of TBI studies found prevalence of obstructive sleep apnea (OSA) was 12 times higher than community-based studies. Yet, sleep apnea in those with TBI is largely undiagnosed. Given that sleep is critical for neural repair and disordered sleep may play a role in slowing functional recovery ...

Phase N/A

Obstructive Sleep Apnea and Glucose Metabolism

Many adults who are overweight have obstructive sleep apnea (OSA) which disrupts sleep and makes it difficult to breath during the night. OSA increases the risk for a person to become insulin resistant and diabetic. It is not known why OSA causes this problem, i.e., whether it is disrupted sleep ...

Phase N/A

Corneal Sensitivity in Patients With Sleep Apnea Syndrome

Screening Assessment: Following the execution of informed consent, subjects will be carefully screened for ocular signs and symptoms, consistent with the protocol inclusion and exclusion criteria. This includes review of ocular and medical history including use of concomitant & ocular medications and surgeries performed in the past. Researchers will also ...

Phase N/A

SORT - AF Supervised Obesity Reduction Trial for AF Ablation Patients

Study protocol: The purpose of this study is to proof a professional care of overweight patients with symptomatic atrial fibrillation, as well as the treatment of the risk factors for atrial fibrillation, especially obstructive sleep apnea and hypertension. There is a 1:1 randomization. In the intervention group, patients are followed ...

Phase N/A

Intraoperative Low-dose Ketamine Infusion for Patients With Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) affects millions of people in the U.S., and currently, there is not a well-established, general anesthetic technique that clearly decreases the risk of postoperative respiratory complications in these patients. If OSA patients have significantly decreased postoperative opioid requirements and improved recovery profiles in the PACU, the ...

Phase