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Helicobacter Pylori Clinical Trials

A listing of Helicobacter Pylori medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (13) clinical trials

Local doctors are looking for people with H. Pylori for clinical research studies of an investigational medication. Must be receiving treatment for H. Pylori Must be at least 18 years old H. Pylori must be present for at least 3 months prior to first visit All patients will receive investigational ...

Phase N/A

Food Effect on the Eradication Rate of H. Pylori With Triple Therapy With Esomeprazole

Phase IV, open, randomized, prospective study. - Length of experience: 180 days. - 06 visits. - Evaluation of the efficacy of differences regimens of administration.

Phase

Feasibility Study of Phototherapy System to Treat H Pylori

H pylori causes almost all peptic ulcers and many gastric cancers and is widely prevalent worldwide. Treatment by multiple antibiotics and proton pump inhibitors is effective but are compromised today by significant non compliance due to side effects and duration of required treatment. Also, the increase in antibiotic resistance coupled ...

Phase N/A

Esomeprazole Moxifloxacin and Amoxicilin for Rescue Therapy of Helicobacter Pylori Infection

Successful H. pylori eradication therapy remains a challenge in medical practice. Currently, a PPI - based triple therapy containing clarithromycin, amoxicillin or nitroimidazole given for 7 days is the recommended first line treatment approach with an expected eradication success rate of approximately 80%. As second-line treatment option in case of ...

Phase

Treating H. Pylori in Parkinson's Patients With Motor Fluctuations

Previous investigations have demonstrated that treatment of Helicobacter pylori with antibiotics leads to improved absorption and pharmacokinetics of levodopa. This may potentially benefit patients with Parkinson's disease who have motor fluctuations, specifically excessive "off" time, when their levodopa is not working to control symptoms. We seek to identify the frequency ...

Phase

Helicobacter Pylori Empiric Treatment in Ulcer Bleeding

The goal of the study is to compare the effectiveness of empirical Helicobacter pylori treatment compared with treatment depending on diagnostic tests for Helicobacter pylori in patients with Upper gastrointestinal bleeding due to peptic ulcer. Main hypothesis is that empirical treatment will reduce the number of patients lost to follow-up ...

Phase

Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori

Current treatment strategies for the eradication of H. pylori include a proton pump inhibitor (PPI) and one or two anti-bacterial agents, such as amoxicillin, clarithromycin, and metronidazole. PPIs, such as lansoprazole and omeprazole, are mainly metabolized in the liver by a genetically determined enzyme, S-mephenytoin 4'-hydroxylase (CYP2C19). Plasma concentrations of ...

Phase

Community-based Helicobacter Pylori Eradication

Despite the decline of global incidence, gastric cancer still affects public health substantially due to the considerable medical burden in the treatment of disease at the symptomatic stage. This fact has prompted clinicians to extend their attention from the multidisciplinary therapies to the design of preventive strategies. Gastric cancer development ...

Phase

Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) Infection

Proton pump inhibitors (PPIs) are mainly metabolized in the liver by CYP2C19, one of the cytochrome P450 isoenzymes, which shows a genetic polymorphism associated with enzyme activities. The most essential role of a PPI in H. pylori eradication therapy is to make antibiotics more stable and bioavailable in the stomach ...

Phase

The Influence of FP-10 on the Eradication Rates of H. Pylori by a Triple Therapy

H. pylori -positive patients older than 15 years of age with gastritis, gastric ulcer, duodenal ulcer, or gastroduodenal ulcer are invited to participate in the study. These patients had endoscopically and histologically proven ulcers or active chronic gastritis and are all H. pylori-positive. Written informed consent to participation must be ...

Phase