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Mitral Valve Regurgitation Clinical Trials

A listing of Mitral Valve Regurgitation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (31) clinical trials

Early Feasibility Study of the Neovasc Tiara Mitral Valve System

This is an international, multicenter, single arm, prospective, Early Feasibility Clinical Study to evaluate the safety and performance of the Neovasc Tiara Mitral Valve System in subjects with symptomatic severe mitral regurgitation requiring mitral valve replacement who are at high risk for open chest surgery. A maximum of 30 subjects ...

Phase N/A

Treatment of Heart Failure and Associated Functional Mitral Valve Regurgitation

The objective of the study is to evaluate the safety and performance of the ARTO System in patients with mitral valve regurgitation (MR) associated with congestive heart failure (CHF).

Phase N/A

Expanded Clinical Study of the Tendyne Mitral Valve System

The purpose of this study is to generate initial insights into the safety and performance of the Tendyne Mitral Valve System. The study includes adult patients with symptomatic mitral regurgitation who are not suitable candidates for conventional mitral valve repair or replacement. The study will include up to 110 subjects ...

Phase N/A

CARILLON Mitral Contour System for Reducing Functional Mitral Regurgitation

The objective of this prospective, multi-center, randomized, double-blind trial is to assess the safety and efficacy of the CARILLON Mitral Contour System in treating functional mitral regurgitation (FMR) associated with heart failure, compared to a randomized Control group which is medically managed according to heart failure guidelines.

Phase N/A

Twelve Transcatheter Mitral Valve Replacement (TMVR) Pilot Study

The study is a prospective, multi-center, non-randomized trial to evaluate the safety and performance of the Twelve TMVR System in very high risk patients with severe, symptomatic mitral regurgitation.

Phase N/A

(MitraClip in Non-Responders to Cardiac Resynchronization Therapy)

STUDY HYPOTHESIS: In patients with no response to CRT and significant FMR (grade ≥2, 100%), the MitraClip system will be associated with improved functional class, LVEF recovery and reduced LV volumes. To our knowledge, no registered randomized studies with a similar design are being conducted. MAIN OBJECTIVE: To compare the ...


AMENDTM Mitral Valve Repair System Annuloplasty Ring Applied in a Transcatheter Method

A multi center study to evaluate the safety of the AMENDTM Mitral Valve Repair System and its ability to reduce mitral regurgitation. AMEND device is an annuloplasty ring implanted in a minimally invasive trans-catheter method.

Phase N/A

Degenerative Mitral Regurgitation in Intermediate Risk Patients

Severe mitral regurgitation is associated with significant morbidity and mortality. Mitral valve surgical repair has proven to be an effective and durable option in the treatment of symptomatic degenerative mitral regurgitation (MR). Echocardiography remains a cornerstone in the evaluation of patients with degenerative (Type II) mitral regurgitation allowing for assessment ...

Phase N/A

Remote Monitoring of Patients With Functional Mitral Regurgitation Undergoing Mitraclip Transcatheter Repair

The scope of the HERMES study is to investigate whether the information obtained by remote monitoring in patients with severe functional mitral regurgitation who have undergone transcatheter mitral valve edge-to-edge repair with the Mitraclip system may have the potential to guide treatment decisions at follow-up visits, and improve the quality ...

Phase N/A

REPAIR - transcatheteR rEPair of mitrAl Insufficiency With caRdioband System

The Cardioband Transcatheter System (Cardioband) is indicated for the treatment of secondary (functional) mitral regurgitation (FMR). The Cardioband is a transcatheter system, deployed on the beating heart through a transseptal approach. The Cardioband is deployed along the posterior annulus of the mitral valve (MV) and is adjusted under trans-esophageal guidance ...

Phase N/A