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Glaucoma Clinical Trials

A listing of Glaucoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (180) clinical trials

Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study

Reduction of intraocular pressure (IOP) with topical antihypertensive medications is the mainstay of initial treatment in patients with OHTN, POAG, and NTG. Many patients, however, continue to experience disease progression despite IOP reduction. Alternative mechanisms of neurodegeneration, including vascular dysregulation and structural susceptibility of the lamina cribrosa, have been proposed ...


Zhongshan Iridocorneal Endothelial Syndrome Study (ICEs)

This is a multi-center study to report the demographic profile, clinical features, and management in patients with Iridocorneal endothelial (ICE) syndrome in China.

Phase N/A

Automatic Self Transcending Meditation (ASTM) Versus Usual Care in Patients With Glaucoma

Glaucoma is a leading cause of irreversible blindness, afflicting an estimated 60.5 million people worldwide. Further, glaucoma is significantly associated with symptoms of depression, altered mood, and anxiety. Meditation, specifically, Automatic Self Transcending Meditation (ASTM) may help reduce depression, anxiety, stress, and may improve quality of life. ASTM is a ...

Phase N/A

Improve Glaucoma Medication Adherence

The purpose if this study is to improve glaucoma medication adherence in Veterans with medically-treated glaucoma. The study design is a single-site randomized controlled trial. Specific Aim 1. Evaluate the impact of an intervention to improve glaucoma medication adherence among Veterans at 6-month follow up. Hypothesis 1: Veterans randomized to ...

Phase N/A

A Study Using Transorbital Alternating Current Stimulation for People With Glaucoma

Participants will engage in baseline, intervention, post-intervention, and follow-up visits over the span of approximately 8 weeks. The expected outcomes for this project are that (1) rtACS activates viable but poorly or non-functional retinal ganglion cells to improve their structural and functional capabilities, (2) measures of retinal, optic nerve, and ...

Phase N/A

PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM)

Number of patients: 51 subjects divided into 3 groups (17 subjects per group) Diagnosis and main inclusion criterion: Diagnosis: Primary open-angle glaucoma or ocular hypertension Main criteria: Patients of either sex Average intraocular pressure (IOP) 36 mm/Hg Previous management with ocular hypotensive medications 2 months, without achieving control (target IOP) ...


Lamina Cribrosa Depth Change With Change in Eye Pressure

Glaucoma patients and control subjects will have their internal eye structure (lamina cribrosa) imaged by optical coherence tomography (OCT) standard images at two different eye pressures. In some participants, the eye pressure will be changed by having the subject drink one liter of tap water quickly with imaging 30 minutes ...

Phase N/A

Monitoring of the IOP After SLT Using iCare Home

Sixty glaucoma patients (POAG and PEX) planned for SLT will be recruited. At baseline, patients will be trained to use the iCare Home tonometer, a handheld device based on rebound tonometry and designed for patients to use at home. After the training session and when patients feel confident, a measurement ...

Phase N/A

A Prospective Evaluation of Glaucoma Subjects Treated With Two Second Generation iStents and One iStent Supra

Prospective Evaluation of Mild to Moderate Open-Angle Glaucoma Subjects treated with Two Second Generation Microbypass Stents and One Suprachoroidal Stent


A Double-Masked Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

To evaluate the effect on trabecular outflow facility of Netarsudil ophthalmic solution 0.02% compared to placebo