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Glaucoma Clinical Trials

A listing of Glaucoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (99) clinical trials

Comparison of Retinal Nerve Fiber Layer (RNFL) Thickness Measurements by Time-Domain and Spectral-Domain OCT In Glaucoma Patients

Measurement of RNFL thickness by OCT is at a cornerstone for the correct diagnosis and monitoring of progression of glaucomatous optic neuropathy. Spectral domain technology has enabled better reproducibility with better axial resolution in the measurement of RNFL thickness. A comparative study among Stratus, Cirrus and RT-View will enable clinicians ...

Phase N/A

Myocilin Variations and Familial Glaucoma in Taxiarchis

Taxiarchis, a small village in Northern Greece with 1060 inhabitants, was considered to have a surprisingly high incidence of glaucoma. This isolated population located on Mount Holomondas appeared to be enriched for familial glaucoma. Based upon the high reported incidence of glaucoma in Taxiarchis and previous findings of the Thr377Met ...

Phase N/A

Study of Endothelial Keratoplasty Outcomes

Endothelial keratoplasty is a cornea-sparing transplant technique that replaces only the diseased endothelial cell layer of the patient's cornea. This technique offers many advantages compared with traditional full-thickness cornea transplants. Patients experience minimal change in glasses prescription and usually recover useful vision within weeks. Visual fluctuations are minimal during the ...

Phase N/A

PASCAL Trabeculoplasty

Argon laser trabeculoplasty (ALT) with 100 ms pulses is an effective therapy for lowering intraocular pressure (IOP). Similar reductions in IOP have been achieved using ns (SLT) and microsecond (MLT) pulses, which produce less thermal damage to trabecular meshwork (TM). Lack of clinically visible changes may make the accurate alignment ...


Prevalence of Angle Closure in Caucasian Hyperopes

Caucasian subjects aged > 40 years with hyperopia will undergo complete eye examination including subjective refraction and gonioscopy. In addition we will measure axial length, anterior chamber depth and lens thickness using ultrasound biometry.

Phase N/A

Evaluation of Pascal Laser Trabeculoplaty

Laser Trabeculoplasty has been shown to be effective in lowering intraocular pressure (IOP) in patients with primary open-angle glaucoma (POAG). Although initially demonstrated with the Argon laser (ALT), several other laser systems have also been employed with comparable efficacy. Recently, Selective Laser Trabeculoplasty (SLT) has been shown to lower intraocular ...

Phase N/A

Ocular Blood Flow in Early Glaucoma Patients Before and After Treatment With Dorzolamide

High intraocular pressure (IOP) is the major risk factor for glaucoma. Lowering intraocular pressure is still the only accepted form of treatment for glaucoma. Over the past decade, epidemiological and experimental evidence suggested that impaired ocular blood flow is an important risk factor with an important role in the pathogenesis ...

Phase N/A

The Genetic Study of Primary Angle-Closure Glaucoma

Glaucoma has long been recognised as a leading cause of blindness, and that the scale of the problem will only increase with future population growth and increasing life expectancy (1). The epidemiological information available in 1993 in the World Health Organization's (WHO) global data bank on blindness was reviewed by ...

Phase N/A

The Results of Ahmed Valve Operations

Glaucoma drainage devices are usually placed in the superior quadrants. The superotemporal quadrant is usually the site of choice. However, when the upper fornix is scarred and especially when conjunctiva is two fibrotic to enable adequate coverage of tube with a scleral or other patch graft, some surgeons place the ...

Phase N/A

Diagnostic Innovations in Glaucoma Study

The purpose of the study is: 1. To further determine the nature of vision loss and optic nerve structural change associated with glaucoma. Using recently developed psychophysical and imaging techniques, we will continue use of a multivariate approach for analysis of the functional and structural changes associated with glaucoma to ...

Phase N/A