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Chronic Obstructive Lung Disease Clinical Trials

A listing of Chronic Obstructive Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (467) clinical trials

This is a randomized, double-blind, multi-center, parallel group study to assess the efficacy and safety of BGF MDI 320/14.4/9.6 μg and BGF MDI 160/14.4/9.6 μg relative to GFF MDI 14.4/9.6 μg and BFF MDI 320/9.6 μg over a 52-week treatment period in 8,000 subjects with moderate to very severe COPD ...

Phase

A Randomized, Double-Blind, Multi-Center, Parallel Group Study to Assess the Efficacy and Safety of PT010 Relative to PT003 and PT009 on COPD Exacerbations over a 52-Week Treatment Period in Subjects With Moderate to Very Severe COPD. ClinicalTrials.gov identifier: NCT02465567 https://www.pearltherapeutics.com/pipeline-overview

Phase N/A

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Safety and Efficacy of 3-Month Subcutaneous REGN1033 Treatment in Patients with Sarcopenia

Phase

This is a research study for chronic obstructive pulmonary disease (COPD). Subjects who meet inclusion criteria will be assigned to one of three doses of tiotropium. Two of these doses will be delivered via a novel inhalation device. The third dose will be delivered by the HandiHaler. This study is ...

Phase N/A

We are looking for individuals to participate in a research study to determine the safety and efficacy of an investigational medication. Eligibility Criteria: If you are: - 40 years of age or older - are a previous or current smoker - have a diagnosis of chronic obstructive pulmonary disease (COPD) ...

Phase N/A

This is a placebo controlled trial to test the efficacy and safety of CHF 5259 (glycopyrronium bromide). This is an 8 week treatment trial.

Phase

The purpose of this study is to compare a FDA approved single therapy inhaler that combines 3 COPD medications to Spiriva for patient convenience. This study is about 3 months long and will consist of 6 office visits. All visits are conducted locally in Salt Lake City, Utah.

Phase

HIV+ Alveolar Macrophage Oxidant-mediated Apoptosis of Pulmonary Endothelium

The purpose of this study is to analyze biologic samples from the blood, airways and/or urine of HIV- and HIV+ smokers and non-smokers to better understand the etiology and pathogenesis of emphysema in association with HIV infection. The underlying hypothesis is that the combination of HIV infection and smoking creates ...

Phase N/A

Integrative-omics of the Disordered COPD Small Airway Epithelium

Hypothesis: We hypothesize that the disordered differentiation of the SAE that characterizes COPD results from the complex interaction of cigarette smoke components with a hierarchy of genetic, epigenetic, gene expression and metabolomics network interactions as the BC differentiate into a mucociliary epithelium. Specific aim 1. Using an integrated network systems ...

Phase N/A

Influence of Mechanical Ventilation Modes on the Efficacy of Nebulized Bronchodilator

2. OBJECTIVES 2.1 Primary To evaluate the influence of mechanical ventilation modes in the efficacy of nebulized bronchodilator in ventilator dependent patients with obstructive pulmonary disease. 2.2 Secondary To compare regional ventilation distribution through Ventilation Surface Area (VSA) and Tidal Impedance Variation (TIV or Z) by electrical impedance tomography (EIT) ...

Phase N/A